Biochemistry News and Research

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Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Ariel Louwrier discusses the development of pre-formed tau and alpha-synuclein fibrils for research into Alzheimer's and Parkinson's disease.

From StressMarq Biosciences Inc. 2 Jan 2020

Plant-rich diet protects against foodborne pathogens, mice study shows

Mice fed a plant-rich diet are less susceptible to gastrointestinal infection from a pathogen such as the one currently under investigation for a widespread E. coli outbreak tied to romaine lettuce, UT Southwestern researchers report.

23 Dec 2019

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Biomolecules -- carbohydrates, proteins, nucleic acids, and lipids -- form the foundation of life and are responsible for carrying out every process that occurs in our bodies.

23 Dec 2019

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

IU scientists discover that beta-carophyllene improves wound healing

Indiana University researchers have discovered that a chemical compound found in essential oils improves the healing process in mice when it is topically applied to a skin wound -- a finding that could lead to improved treatments for skin injuries in humans.

18 Dec 2019

Genetic mystery of infertility in fruit flies discovered

Researchers have discovered a novel parasitic gene in fruit flies that is responsible for destroying the eggs in the ovaries of their daughters.

17 Dec 2019

Houston professor uses stem cells to develop next-generation biologic pacemakers

University of Houston associate professor of pharmacology Bradley McConnell is helping usher in a new age of cardiac pacemakers by using stem cells found in fat, converting them to heart cells, and reprogramming those to act as biologic pacemaker cells.

17 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

UAB seminar on the extraordinary science of the immune system

"The human immune system makes my head explode," Pulitzer Prize-winning journalist Matt Richtel recently told a University of Alabama at Birmingham freshman seminar on immunology. "This is by far the hardest subject I have ever had to explore."

15 Dec 2019

Molecular subtyping of bladder tumors outperformed by standard pathology tests

While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found that sophisticated new subtyping techniques designed to do this provide no better information than long-standing pathology tests.

14 Dec 2019

Scientists solve 3D structure of vaccinia virus RNA polymerase

For viruses to multiply, they usually need the support of the cells they infect. In many cases, only in their host's nucleus can they find the machines, enzymes and building blocks with which they can multiply their genetic material before infecting other cells.

12 Dec 2019

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

Researchers from The University of Texas Medical Branch at Galveston showed, for the first time, that a single, higher dose of vaccination to a pregnant mouse safely protects both her and her fetus from the Zika virus.

12 Dec 2019

Molecular drills target and destroy deadly superbugs

Molecular drills have gained the ability to target and destroy deadly bacteria that have evolved resistance to nearly all antibiotics. In some cases, the drills make the antibiotics effective once again.

12 Dec 2019

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

11 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

Award to help advance development of diagnostic test for necrotizing enterocolitis

The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has awarded Chosen Diagnostics Inc, a spin-out company, a $299,641 Phase I Small Business Technology Transfer award.

9 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

Goethe University researchers develop new method to measure acute cellular changes

When cells are stressed, they initiate a complex and precisely regulated response to prevent permanent damage. One of the immediate reactions to stress signals is a reduction of protein synthesis (translation). Until now, it was difficult to measure such acute cellular changes. As reported in the latest online issue of the renowned journal Molecular Cell, researchers at Goethe University have now developed a method overcoming this hurdle.

5 Dec 2019

Tel Aviv Professor receives Young Investigator Award for contributions in melanoma research

Tel Aviv University's Prof. Carmit Levy received the prestigious Young Investigator Award at the 16th International Congress of the Society for Melanoma Research, held November 20-23 in Salt Lake City, Utah, for her "contributions to melanoma research that significantly exceeded the average for this career stage."

5 Dec 2019

GW-led consortium receives $2.2 million from FDA for Biocompute Object Specification Project

A consortium led by the George Washington University (GW) has been refunded for their BioCompute Object Specification Project, thanks to a $2.2 million, five-year grant from the U.S. Food and Drug Administration.

4 Dec 2019

Biochemistry News and Research

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Plant-rich diet protects against foodborne pathogens, mice study shows

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Catastrophic macropinocytosis may aid in cancer treatment

IU scientists discover that beta-carophyllene improves wound healing

Genetic mystery of infertility in fruit flies discovered

Houston professor uses stem cells to develop next-generation biologic pacemakers

New tool gives more reliable and precise results in cancer research

UAB seminar on the extraordinary science of the immune system

Molecular subtyping of bladder tumors outperformed by standard pathology tests

Scientists solve 3D structure of vaccinia virus RNA polymerase

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

Molecular drills target and destroy deadly superbugs

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Award to help advance development of diagnostic test for necrotizing enterocolitis

The role of adenosine in neurodegeneration and brain regeneration

Goethe University researchers develop new method to measure acute cellular changes

Tel Aviv Professor receives Young Investigator Award for contributions in melanoma research

GW-led consortium receives $2.2 million from FDA for Biocompute Object Specification Project

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