Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH).

25 Nov 2016

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.

23 Nov 2016

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.

22 Nov 2016

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood.

18 Nov 2016

New research helps explain possible mechanism for recurrence of breast cancer

In October, we mourned those who died of breast cancer and celebrated all of the women (and men) who have survived. What many of those survivors worry about, though, is that their breast cancer may come back.

15 Nov 2016

BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

For the first time, researchers have shown that using Magnetic Resonance Imaging (MRI) can effectively identify bone marrow cancer (myelofibrosis) in an experimental model.

14 Nov 2016

New research uncovers role of spleen in long-term anxiety following psychological stress

Scientists are uncovering clues to what might be unfolding in the relationship between the brain and immune system in those who suffer from long-term repercussions of stress.

14 Nov 2016

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles, has been awarded a 3 year translational research program grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL).

10 Nov 2016

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist and cancer researcher Robert L. Harrod has been awarded a $436,500 grant from the National Cancer Institute to further his lab's research into how certain viruses cause cancers in humans.

8 Nov 2016

ASH partners with other organizations to address knowledge gaps in AML care

The American Society of Hematology has partnered with several organizations on independent educational programming designed to help address knowledge gaps in the diagnosis and treatment of acute myeloid leukemia (AML).

8 Nov 2016

Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient's own stem cells showed that the therapy appears to dampen the body's neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston.

4 Nov 2016

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

University of Hawai'i Cancer Center researchers discovered a novel therapeutic target and treatment strategy for acute myeloid leukemia, a cancer of the blood and bone marrow that normally requires prompt and aggressive treatment.

2 Nov 2016

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

Fred Hutchinson Cancer Research Center today announced the official opening of a first-of-its-kind clinic dedicated to providing innovative immunotherapies for cancer patients in clinical trials.

2 Nov 2016

Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML.

27 Oct 2016

Researchers develop new way to test strength of immune response

The immune system orchestrates large and small scale attacks on innumerous targets: viruses, bacteria, cancer, but it also misfires causing allergy or autoimmune reactions.

27 Oct 2016

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

26 Oct 2016

Researchers identify negative role of oxidation in new blood cells

Oxygen in the air is well known to cause damaging rust on cars through a process known as oxidation.

24 Oct 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Researchers at the Medical University of South Carolina Hollings Cancer Center have discovered a mechanism that confers resistance to drugs used to treat certain types of acute myeloid leukemia (AML).

24 Oct 2016

Bone Marrow News and Research

Further Reading

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

Cancer gene mutations can predict response to less intensive treatment in AML patients

HSCI researchers use color tagging system to track development of blood stem cells

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research helps explain possible mechanism for recurrence of breast cancer

BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

New research uncovers role of spleen in long-term anxiety following psychological stress

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

ASH partners with other organizations to address knowledge gaps in AML care

Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden

Researchers develop new way to test strength of immune response

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

Researchers identify negative role of oxidation in new blood cells

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Novel lipid-based therapeutic shows promise for combating drug resistance in AML

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News