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NSAIDs linked to longer survival for certain colorectal cancer patients

Among long-term colorectal cancer survivors, use of nonsteroidal anti-inflammatory drugs, or NSAIDs, is associated with about a 25 percent reduction in all-cause mortality, according to new research from Fred Hutchinson Cancer Research Center published online in the Journal of Clinical Oncology.

16 Jun 2017

New research could help mitigate effects of radiation therapy

New research conducted at the University of Kansas Medical Center could make treatment for gastrointestinal cancers safer- while also helping to mitigate the dangers of nuclear accidents and terrorist attacks.

14 Jun 2017

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina in the May 19, 2017 issue of Scientific Reports.

14 Jun 2017

New treatment strategy may destroy difficult-to-treat brain tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center.

13 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response in mice.

8 Jun 2017

Study reveals cancer-fighting power of onions

The next time you walk down the produce aisle of your grocery store, you may want to reach for red onions if you are looking to fight off cancer.

7 Jun 2017

New findings highlight possibility of developing specific cancer drugs with fewer side effects

Scientists at Karolinska Institutet in Sweden report that cancer cells and normal cells use different 'gene switches' in order to regulate the expression of genes that control growth.

6 Jun 2017

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

After surgery for lymph-node positive colon cancer (stage III), some patients may only need half of the long-standing standard course of chemotherapy.

5 Jun 2017

New targeted oral therapy results in durable responses across many kinds of cancer

Scientists may have developed the first targeted, oral, tumor-type agnostic therapy - a cancer medicine that works comparably well across many kinds of cancer, regardless of patient age. In clinical trials of adults and children with 17 different types of advanced cancer, larotrectinib treatment resulted in responses in 76% of patients.

5 Jun 2017

Study: Child's gut bacteria appears to be influenced by ethnicity and breastfeeding

The bacteria in a child's gut appears to be influenced as early as its first year by ethnicity and breastfeeding, according to a new study from McMaster University.

1 Jun 2017

MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017

Study: Type 2 diabetes linked to bacteria that penetrate mucus lining of the colon

In humans, developing metabolic disease, particularly type 2 diabetes, is correlated with having bacteria that penetrate the mucus lining of the colon, according to a study led by Drs. Benoit Chassaing and Andrew Gewirtz at Georgia State University.

30 May 2017

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday).

29 May 2017

Researchers can attack cancer by working together, says UNC Charlotte professor

MUC1 is a protein present on the cells that line most organs. It lubricates and protects them. When cells become malignant, the MUC1 protein changes and signals tumor cells to multiply.

27 May 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

Colon News and Research

NSAIDs linked to longer survival for certain colorectal cancer patients

New research could help mitigate effects of radiation therapy

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

New treatment strategy may destroy difficult-to-treat brain tumors

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Study reveals cancer-fighting power of onions

New findings highlight possibility of developing specific cancer drugs with fewer side effects

Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery

New targeted oral therapy results in durable responses across many kinds of cancer

Study: Child's gut bacteria appears to be influenced by ethnicity and breastfeeding

MGH scientists show how Shigella survives journey from mouth to the colon

Study: Type 2 diabetes linked to bacteria that penetrate mucus lining of the colon

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Researchers can attack cancer by working together, says UNC Charlotte professor

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

New study finds dramatic reorganization of the gut caused by weight loss surgery

FDA grants accelerated approval to cancer treatment based on common biomarker

Study shows new promise in the fight against pancreatic cancer

New finding could lead to more effective treatment decisions for younger colorectal cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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