Immune Response News and Research

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The impact of viral infections on the human endocrine system

Researchers briefly outlined how viral infections trigger endocrinopathies in humans.

3 Feb 2023

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Patients with glioblastoma - the deadliest type of primary brain tumor - may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

2 Feb 2023

Researchers identify a gene that drives T lymphocytes to exhaustion

A research group funded by the Swiss National Science Foundation has identified a gene that drives T lymphocytes to exhaustion. This opens up new approaches for more effective immunotherapies.

2 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

Researchers develop new way to increase the potency of cancer vaccines

A new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology (IIN) at Northwestern University.

31 Jan 2023

New technique offers a two-prong approach to attacking cancers

When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall "cloak," the treatment exposes cancer cell markers that had previously been hidden from the body's defenses, researchers at the University of Michigan have shown.

31 Jan 2023

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers determine whether protein expression in nasal fluid samples could assist in the diagnosis of severe asthma subtypes.

31 Jan 2023

New EV platform could help streamline the development and delivery of vaccines worldwide

To many, EV stands for "electric vehicle." To researchers at Harvard University and the University of Nebraska–Lincoln, it's shorthand for another vehicle - this one nanoscopic - that might help streamline the development and delivery of vaccines worldwide.

30 Jan 2023

Experimental vaccine against Marburg virus shows promise in first-in-human clinical trial

A newly published paper in The Lancet shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial.

30 Jan 2023

Study shows COVID-19 induces body fat and other metabolic changes

In a recent study published in the journal Cureus, researchers explored the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and levels of serum insulin, body fat distribution, and insulin resistance (IR) estimated by homeostasis model assessment (HOMA).

29 Jan 2023

Study evaluates SARS-CoV-2-specific antibody response in human milk

In a recent study published in the journal Communications Biology, researchers investigated the effect of the coronavirus disease 2019 (COVID-19) vaccine booster on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the milk of lactating women. Additionally, they explored whether the booster-induced antibody response differed from the homologous and heterologous boosting schedule of their primary vaccination.

29 Jan 2023

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

The immunologic milieu of pregnancy has no effect on the durability of the anti-S IgG response to COVID-19 vaccination

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Children’s immune systems do not develop ‘adaptive’ memory to protect against second time SARS-CoV-2 infection

Children have largely avoided severe COVID-19 symptoms because they have a strong initial 'innate' immune reaction that quickly defeats the virus.

26 Jan 2023

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally.

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Researchers assessed the impact of SARS-CoV-2 vaccination on pregnant women during the Omicron wave.

25 Jan 2023

Immune Response News and Research

The impact of viral infections on the human endocrine system

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Researchers identify a gene that drives T lymphocytes to exhaustion

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

Researchers develop new way to increase the potency of cancer vaccines

New technique offers a two-prong approach to attacking cancers

A machine-learning approach to identify asthma subtypes based on molecular signatures

New EV platform could help streamline the development and delivery of vaccines worldwide

Experimental vaccine against Marburg virus shows promise in first-in-human clinical trial

Study shows COVID-19 induces body fat and other metabolic changes

Study evaluates SARS-CoV-2-specific antibody response in human milk

Pregnancy has no effect on long-term immune response to SARS-CoV-2 mRNA vaccination

Activated neutrophils can become potent cancer fighters

Children’s immune systems do not develop ‘adaptive’ memory to protect against second time SARS-CoV-2 infection

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

Maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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