Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

Dietary broccoli may protect against liver cancer

Consumption of broccoli has increased in the United States over the last few decades as scientists have reported that eating the vegetable three to five times per week can lower the risk of many types of cancer including breast, prostate, and colon cancers.

4 Mar 2016

Lewin-Cameron Laboratory at Doherty Institute selects OpenSpecimen system to manage biospecimens inventory

In the short time that AXT have been promoting OpenSpecimen, the bioinformatics platform for managing biospecimens inventory developed by Krishagni Solutions in conjunction with the National Cancer Institute, it has generated large amounts of interest in Australia.

From AXT Pty Ltd 2 Mar 2016

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens" -- the proteins triggering an immune attack -- have been linked to JIA.

27 Feb 2016

Light-to-moderate drinking can be good for your heart

Drinking a little alcohol every day may be part of a healthy lifestyle, according to Imre Janszky, a professor of social medicine at the Norwegian University of Science and Technology. He says alcohol does more good than harm for your heart when consumed in moderation.

23 Feb 2016

Three to five drinks a week good for your heart

People who drink wine, liquor or beer regularly are less prone to heart failure and heart attacks than those who rarely or never drink.

18 Feb 2016

Aerobic exercise may prevent alcohol-related liver damage

According to the Centers for Disease Control and Prevention, excessive alcohol use is responsible for more than 80,000 deaths in the United States each year. Over time, excessive drinking can lead to several chronic conditions, such as fatty liver disease and cirrhosis.

16 Feb 2016

Iroko announces availability of VIVLODEX capsules in U.S. pharmacies for patients with OA pain

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, announced today that VIVLODEX (meloxicam) capsules, a nonsteroidal anti-inflammatory drug (NSAID), is now available by prescription at pharmacies across the United States.

16 Feb 2016

Alcohol appears to impair the body's ability to keep gut bacteria in check

Alcohol itself can directly damage liver cells. Now researchers at University of California, San Diego School of Medicine report evidence that alcohol is also harmful to the liver for a second reason — it allows gut bacteria to migrate to the liver, promoting alcohol-induced liver disease.

11 Feb 2016

Cancer patients who miss scheduled radiation therapy appointments have worse outcomes

Cancer patients who miss two or more radiation therapy sessions have a worse outcome than fully compliant patients, investigators at Montefiore Einstein Center for Cancer Care and Albert Einstein College of Medicine's NCI-designated Albert Einstein Cancer Center have found.

10 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Incidence and severity emerging CVD risk factors may differ between genders

The incidence and severity of both traditional and emerging cardiovascular disease (CVD) risk factors as well as the response to treatment may differ between genders. In this narrative review, several emerging CVD risk factors (i.e. inflammatory and haemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease) are discussed in the context of gender differences.

5 Feb 2016

Potential treatment target identified for fatty liver disease

Two proteins, p38 gamma and p38 delta, control the accumulation of fat in the liver, a process linked to the development of insulin resistance and diabetes, which are common outcomes of obesity. These findings are presented in an article published by researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC).

4 Feb 2016

Genetic profiling ‘feasible’ for paediatric cancer patients

Research published in JAMA Oncology demonstrates that tumour and germline molecular profiling is feasible in paediatric cancer patients and can have actionable findings.

2 Feb 2016

SLU clinical psychologist helps patients battle fears, phobias

Some fear is rational, keeping us appropriately cautious in the face of dangerous animals, hot stoves and contagions that could make us ill. But rational caution can turn to irrational panic about imagined terrors that are unlikely to occur or cause much actual damage if they did.

31 Jan 2016

UCL-led researchers find way to assess viability of induced pluripotent stem cells

A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). Published today in Nature Communications, the team's discovery offers a new way to fast-track screening methods used in stem cell research.

30 Jan 2016

Beta- and gamma-HPVs associated with development of head and neck cancers, finds Einstein study

Researchers at Albert Einstein College of Medicine have found that when human papillomavirus (HPV)-16 is detected in peoples' mouths, they are 22 times more likely than those without HPV-16 to develop a type of head and neck cancer.

22 Jan 2016

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

In results published on October 19, 2015 in the Journal of Lipid Research, a team of translational scientists at the Medical University of South Carolina report a new reason why non-alcoholic steatohepatitis (NASH) worsens in people who are obese.

20 Jan 2016

Researchers engineer antibodies that could potently neutralize two deadliest strains of Ebola virus

Researchers at Albert Einstein College of Medicine and the U.S. Army Medical Research Institute of Infectious Diseases have engineered the first antibodies that can potently neutralize the two deadliest strains of the virus that causes Ebola hemorrhagic fever.

13 Jan 2016