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ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Researchers demonstrated the inhalation of an ACE2 decoy receptor, sACE22.v2.4-IgG1, increases survival and ameliorates lung injury in K18-hACE2 transgenic mice.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Lung abnormalities may remain detectable long after COVID-19 pneumonia

Some people recovering from COVID-19 pneumonia have CT evidence of damage to their lungs that persists a full year after the onset of symptoms, according to a new study published in the journal Radiology.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers have shown a new compound delivered in a nasal spray is highly effective in preventing and treating COVID-19 caused by the Delta variant in mice.

29 Mar 2022

The effects of severe COVID-19 on the lungs after one year

While short-term lung damage has been reported in patients hospitalized with pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is little data on the more chronic sequelae of this condition. A new research paper summarizes data from patients seen one year from discharge.

27 Mar 2022

Tuberculosis infection protects mice against COVID-19

To study if prior Mtb infection affects the response to CoV2 infection, K18-hACE2 (ACE2) and C57BL/6 (B6) mice were infected with Mtb, and post thirty days, were exposed to CoV2.

27 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

Tuberculosis perturbs epigenetic processes to promote premature cellular aging

Tuberculosis (TB) is a potentially serious infectious disease caused by a type of bacterium called Mycobacterium tuberculosis.

24 Mar 2022

U of A researcher receives $436,642 from NIH to study effects of SARS-COV-2 on the aortic valve

The National Institute of Health awarded $436,642 to associate professor of biomedical engineering, Kartik Balachandran, to study the downstream effects of acute respiratory syndrome coronavirus 2 on the aortic valve.

24 Mar 2022

Short duration treatment effective in combating most childhood TB cases, study says

Short duration treatment — four months instead of the standard six — is as effective in combating most cases of childhood tuberculosis (TB), says a study carried out in India and some African countries.

24 Mar 2022

World Tuberculosis Day 2022: an interview with Dr. Maxine Caws

For World Tuberculosis Day 2022, News Medical spoke to Dr. Maxine Caws to raise awareness of this infectious disease.

24 Mar 2022

World Tuberculosis Day 2022: an interview with Dr. Michael Lauzardo

For World Tuberculosis Day 2022, News Medical spoke to Dr. Michael Lauzardo, director of the Southeastern National TB Center, to raise awareness of this infectious disease.

24 Mar 2022

Researchers aim to study the underlying pathophysiology of diastolic heart failure

Of the estimated five million patients in the U.S. diagnosed with heart failure annually, nearly half will have heart failure with preserved ejection fraction (HFpEF). Also known as diastolic heart failure, HFpEF occurs when the heart's lower left chamber loses its ability to relax and fill up with enough blood in between in each heartbeat.

23 Mar 2022