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Diabetes and tooth loss contribute to faster cognitive decline in older adults

Having both diabetes and tooth loss contributes to worse cognitive function and faster cognitive decline in older adults, according to a new study published in a special issue of the Journal of Dental Research focused on aging and oral health.

13 Mar 2023

A review on two novel eating disorders

Researchers review existing data on avoidant/restrictive food intake disorder (ARFID) and atypical-type anorexia nervosa (AN).

13 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

This new article publication from Acta Pharmaceutica Sinica B, discusses the development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.

9 Mar 2023

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections.

9 Mar 2023

Gender inequalities in the diagnosis and treatment of peripheral artery disease

Treatments for peripheral artery disease (PAD) were largely developed in men and are less effective in women, according to a review published today in European Heart Journal – Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology.

8 Mar 2023

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

Enhanced recovery programs (ERPs) provide hospitals with the highest-quality resources to improve patient care for surgery, but many hospitals still struggle to successfully implement these programs and may need more structured resources to boost compliance rates, according to findings published in the Journal of the American College of Surgeons.

8 Mar 2023

Does ingested fluoride affect the human microbiome?

Researchers discuss the effect(s) of fluoride exposure on the human microbiome.

7 Mar 2023

Statin-related residual inflammation predicts cardiovascular events and mortality

A recent Lancet study assessed the importance of low-density lipoprotein cholesterol (LDLC) and high-sensitivity C-reactive protein (CRP) as risk predictors of cardiovascular death, cardiovascular events, and all-cause death among patients subjected to statins.

7 Mar 2023

Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

The current study aimed to explore the contraceptive potential of the human contraceptive antibody-containing vaginal film called ZB-06.

7 Mar 2023

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

High-dose anticoagulation can reduce deaths by 30 percent and intubations by 25 percent in hospitalized COVID-19 patients who are not critically ill when compared to the standard treatment, which is low-dose anticoagulation.

6 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

Giving noncritically ill patients hospitalized for COVID-19 a higher dose of blood-thinning medication than usual did not significantly reduce the combined risk of death from any cause, need for treatment in an intensive-care unit, a confirmed blood clot or a stroke at 30 days, according to the results of the FREEDOM-COVID trial presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

What is the impact of oral cannabidiol on simulated driving?

Researchers assessed the impact of cannabidiol on the driving performance of humans.

6 Mar 2023

Study summarizes two cases of Cronobacter illness in infants linked to powdered infant formula and breast pump equipment

The findings indicate that C. sakazakii bacteria are common in the environment, and protocols for safe and hygienic food preparation for infants are essential.

6 Mar 2023

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

A new study in Frontiers in Neurology aimed to review the available studies which support the clinical utility of ketogenic interventions in PD, MCI, and AD.

5 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

This dental device was sold to fix patients’ jaws. Lawsuits claim it wrecked their teeth.

Boja Kragulj, an accomplished clarinetist who once performed with orchestras in New York, Philadelphia, and Jacksonville, Florida, has already lost four teeth. And she expects to lose at least a dozen more.

1 Mar 2023

Oral News and Research

Diabetes and tooth loss contribute to faster cognitive decline in older adults

A review on two novel eating disorders

What is the effect of low Anti-Müllerian hormone on semen quality?

Inhibition of ACLY by 326E represents a promising strategy for treatment of hypercholesterolemia

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

Gender inequalities in the diagnosis and treatment of peripheral artery disease

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

Does ingested fluoride affect the human microbiome?

Statin-related residual inflammation predicts cardiovascular events and mortality

Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

CDC recommendations and clinical considerations for the treatment of severe Mpox

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

What is the impact of oral cannabidiol on simulated driving?

Study summarizes two cases of Cronobacter illness in infants linked to powdered infant formula and breast pump equipment

Therapeutic ketosis for mild cognitive impairment, Alzheimer's and Parkinson's

Clinical study reveals new use for high blood pressure drug in pediatric patients

This dental device was sold to fix patients’ jaws. Lawsuits claim it wrecked their teeth.

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