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Researchers identify a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

8 Feb 2022

Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

In a new study, a team of researchers assessed the differences in risk of hospitalization in adults after infection with SARS-CoV-2 Omicron and Delta variants.

8 Feb 2022

Exploring the high incidence of croup in children during the SARS-CoV-2 Omicron wave

In a new study, researchers observed that the incidence of pediatric croup was higher during the latest surge of COVID-19 infections driven by the SARS-CoV-2 Omicron variant.

8 Feb 2022

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

SARS-CoV-2 in the exhaled breath of COVID-19 patients might be mainly transmitted via respiratory droplets

Researchers found evidence that SARS-CoV-2 particles are released directly into the air through the breathing of COVID-19 patients resulting in respiratory transmission of the virus.

8 Feb 2022

Transmission dynamics of Omicron SARS-CoV-2 variant in England during January 2022

Researchers utilized data from the recent rounds of the REACT-1 study to document the transmission dynamics of SARS-CoV-2, mainly focusing on the Omicron variant in England during January 2022.

8 Feb 2022

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

In a recent study published in the journal ACS Applied Bio Materials, researchers demonstrated the inhibitory potential of curcumin-encapsulated polysaccharide nanoparticles (CUR−PS-NPs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (CoV2-SP)-stimulated cytokine storm in lung and liver epithelial cells.

8 Feb 2022

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

The fight against the COVID-19 pandemic is an international scientific challenge regarding the search for strategies to fight the viral infection and prevent its damaging consequences.

7 Feb 2022

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

Researchers assess the different clinical symptoms of SARS-CoV-2 infection in children and adolescents across different time periods.

7 Feb 2022

Study looks at rapid antigen vs. PCR tests in the emergency department triage

In a recent study posted to the Lancet preprint* server, researchers assessed the utility of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) rapid antigen testing (RAT) for patient triage in the hospital emergency department (ED).

7 Feb 2022

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

A recent study posted to the Research Square* preprint server and under consideration for inclusion in the journal Scientific Reports assessed the epidemiology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) reinfections.

6 Feb 2022

Scientists reveal how droplets of transcription factors collectively read DNA regions to switch on genes

Life starts with one cell. When an organism develops, dividing cells specialize to form the variety of tissues and organs that build up the adult body, while keeping the same genetic material – contained in our DNA.

6 Feb 2022

Exploring the comparative efficacy of booster vaccines against SARS-CoV-2 Omicron and Delta variants

In a new study, researchers assessed the effectiveness of SARS-CoV-2 Omicron and Delta variants.

4 Feb 2022

Investigation of SARS-CoV-2 outbreak in UK office highlights the need for a site-specific COVID-19 prevention strategy

In a new study, researchers comprehensively investigated a public-facing office in England where a SARS-CoV-2 outbreak occurred during August-September 2021 to identify workplace and worker-related risk factors.

4 Feb 2022

Study shows SARS-CoV-2 infection can change nasopharyngeal microbiota composition in pregnancy

A recent study from Spain showed that the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can change the overall structure and diversity of the nasopharyngeal microbiota in pregnant women – which persists even weeks after clinical infection. The paper is currently available on Research Square preprint* server.

3 Feb 2022

Transcription News and Research

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Antibody drug improves survival rates in canine prostate cancer model

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

Exploring the high incidence of croup in children during the SARS-CoV-2 Omicron wave

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

SARS-CoV-2 in the exhaled breath of COVID-19 patients might be mainly transmitted via respiratory droplets

Transmission dynamics of Omicron SARS-CoV-2 variant in England during January 2022

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

Study looks at rapid antigen vs. PCR tests in the emergency department triage

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

Scientists reveal how droplets of transcription factors collectively read DNA regions to switch on genes

Exploring the comparative efficacy of booster vaccines against SARS-CoV-2 Omicron and Delta variants

Investigation of SARS-CoV-2 outbreak in UK office highlights the need for a site-specific COVID-19 prevention strategy

Study shows SARS-CoV-2 infection can change nasopharyngeal microbiota composition in pregnancy

Understanding public responses to UK's COVID test, trace and isolate measures

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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