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Sex differences in gray matter reductions may underlie risk of substance abuse in adolescents with bipolar disorder

A new study has found that adolescents suffering from bipolar disorder are more likely to develop substance use disorders if they have lower gray matter volume in the brain, a clue that can help in the design of better methods for early detection and more targeted prevention and treatment.

10 Nov 2016

Cannabinoid receptors regulate memory processes by modulating mitochondrial energy metabolism

It has been known for some time that the extracts of the Cannabis plant, just like synthetic cannabinoids and those produced by the brain itself, join up with type 1 (CB1) cannabinoid receptors located in the nerve endings of the neurons, and inhibit the release of chemical messengers (neurotransmitters) in the communication areas between the nerve cells.

10 Nov 2016

Bone gene in mammals may take additional role to promote cognition in humans

A gene that regulates bone growth and muscle metabolism in mammals may take on an additional role as a promoter of brain maturation, cognition and learning in human and nonhuman prim ates, according to a new study led by neurobiologists at Harvard Medical School.

9 Nov 2016

Study elucidates why women have higher risk of developing Alzheimer's disease than men

Women have a two-fold higher risk of developing Alzheimer's disease than men, yet strikingly little is known about how changes in brain function promote this difference -- and how early in midlife those changes can be detected.

9 Nov 2016

Research reveals mechanism behind progression of neurodegenerative diseases in the brain

Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer's to spread through the brain.

9 Nov 2016

First month after infection is key period to control drug-related HIV spread, research reveals

Data from the mid-1990s AIDS epidemic in Russia and Ukraine shows that the first month after infection is the key period to control the spread of the virus in drug-using populations, according to a new study by researchers at Oxford University.

9 Nov 2016

UMass Amherst scientist wins 2016 Pearl Award for research on issues concerning endocrine disruptors

The Cornell Douglas Foundation, an environmental health and justice advocacy group based in Bethesda, Md., has named University of Massachusetts Amherst environmental health scientist Laura Vandenberg one of its 2016 Pearl Award winners in recognition of her "outstanding leadership in conducting critical research to identify and address the many issues concerning endocrine disruptors."

8 Nov 2016

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist and cancer researcher Robert L. Harrod has been awarded a $436,500 grant from the National Cancer Institute to further his lab's research into how certain viruses cause cancers in humans.

8 Nov 2016

Researchers discover genetic alterations in autism gene that reduces brain activity

Scientists at McMaster University's Stem Cell and Cancer Research Institute in collaboration with Sick Children's Hospital have discovered genetic alterations in the gene DIXDC1 in individuals with autism spectrum disorders (ASD).

8 Nov 2016

Single gene therapy for lipoprotein lipase deficiency reduces severity and frequency of pancreatitis

Over a 6-year period, patients with the genetic disease lipoprotein lipase deficiency (LPLD) who received a single gene therapy treatment of alipogene tiparvovec had a marked reduction in the severity and frequency of pancreatitis.

8 Nov 2016

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Amyotrophic lateral sclerosis (ALS) is an adult onset, fetal neurodegenerative disease that selectively affects motor neurons.

8 Nov 2016

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients.

8 Nov 2016

Researchers unravel puzzle of necroptosis

Cell death is an essential physiological process for all multicellular organisms. Throughout life, cells in many tissues die naturally and are replaced by new cells.

8 Nov 2016

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

An international research team led by St. Jude Children's Research Hospital investigators has uncovered details of a new, high-risk subtype of acute lymphoblastic leukemia (ALL) as well as a possible targeted therapy.

8 Nov 2016

Cannabis abuse linked to risk of developing psychosis

The risk of developing psychosis is more than tripled for those who abuse cannabis, according to results from a new twin study.

8 Nov 2016

Advances in RNA research could pave new way for development of anti-cancer drugs

An international research team led by the University of Leicester has made a breakthrough advance that could pave a new route for the development of anti-cancer drugs.

8 Nov 2016

Novel technique helps scientists find genetic variants linked to disease

Some 10 million points of genetic variation are scattered across a molecule of DNA, and those variations make us who we are as individuals. But in some cases, those variants contribute to diseases, and it's a major challenge for scientists to distinguish between harmless variants and those that are potentially hazardous to our health.

8 Nov 2016

Scientists develop new computer-based method to assess cell communication networks

A multi-institution academic-industrial partnership of researchers led by Case Western Reserve University School of Medicine has developed a new method to broadly assess cell communication networks and identify disease-specific network anomalies.

8 Nov 2016

Researchers shed light on how success of gut microbiome treatments may depend on genetics

Our gut microbiomes--the bacteria that live in our digestive tract--play major roles in our health. Scientists around the world are studying therapies that manipulate the microbiome, including probiotics (such as live bacterial cultures in yogurt), prebiotics (edible fibers meant to promote beneficial bacteria), antibiotics and transplants of microbes from healthy people.

7 Nov 2016

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

7 Nov 2016

Genetic News and Research

Sex differences in gray matter reductions may underlie risk of substance abuse in adolescents with bipolar disorder

Cannabinoid receptors regulate memory processes by modulating mitochondrial energy metabolism

Bone gene in mammals may take additional role to promote cognition in humans

Study elucidates why women have higher risk of developing Alzheimer's disease than men

Research reveals mechanism behind progression of neurodegenerative diseases in the brain

First month after infection is key period to control drug-related HIV spread, research reveals

UMass Amherst scientist wins 2016 Pearl Award for research on issues concerning endocrine disruptors

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

Researchers discover genetic alterations in autism gene that reduces brain activity

Single gene therapy for lipoprotein lipase deficiency reduces severity and frequency of pancreatitis

Collapse of MAM is common pathological hallmark to certain inherited forms of ALS

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

Researchers unravel puzzle of necroptosis

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

Cannabis abuse linked to risk of developing psychosis

Advances in RNA research could pave new way for development of anti-cancer drugs

Novel technique helps scientists find genetic variants linked to disease

Scientists develop new computer-based method to assess cell communication networks

Researchers shed light on how success of gut microbiome treatments may depend on genetics

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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