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Abnormalities of blood vessels in the brain may play major role in development of schizophrenia

Scientists from Trinity College Dublin and the Royal College of Surgeons in Ireland have discovered that abnormalities of blood vessels in the brain may play a major role in the development of schizophrenia, a debilitating condition that affects around 1% of people in Ireland.

10 Oct 2017

Common acid reflux drugs linked to progression of chronic liver disease

Approximately 10 percent of the general population take a proton pump inhibitor (PPI) drug to block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux and gastroesophageal reflux disease.

10 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

New insights into rare-among-rare genetic bone disorder

I have been writing about conditions that cause out-of-place bone formation for over 10 years – since the discovery of the gene in 2006 for the rare bone disorder, FOP (fibrodysplasia ossificans progressive). But it was while interviewing geneticist Eileen Shore, PhD last spring about another bone disorder, progressive osseous heteroplasia, or POH, that it really hit me how much more rare POH is compared to FOP.

10 Oct 2017

Improving synchronization of brain waves enhances learning and self-control

Robert Reinhart calls the medial frontal cortex the "alarm bell of the brain." "If you make an error, this brain area fires," says Reinhart, an assistant professor of psychological and brain sciences at Boston University. "If I tell you that you make an error, it also fires.

10 Oct 2017

Medicare plans place few restrictions on coverage of prescription opioids, Yale study finds

Medicare plans place few restrictions on the coverage of prescription opioids, despite federal guidelines recommending such restrictions, a new Yale study finds. The research results highlight an untapped opportunity for Medicare formularies to limit opioid prescribing, the researchers said.

10 Oct 2017

Cells lining blood vessels in the lungs exposed to bacterial toxins don’t die easy, UIC study says

Cells lining blood vessels in the lungs that are exposed to bacterial toxins don't die easy, according to a new study led by researchers at the University of Illinois at Chicago College of Medicine.

10 Oct 2017

New law challenges ‘evils’ of pharma profits, California governor claims

California Gov. Jerry Brown defied the drug industry Monday by signing a sweeping drug price transparency bill that will force drugmakers to publicly justify big price hikes.

9 Oct 2017

Shifting toward novel pricing models that closely link drug's price to its value

One of the health care issues about which seemingly all Americans agree: Prescription drug prices have skyrocketed. And they keep going higher.

9 Oct 2017

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells.

9 Oct 2017

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's disease, scientists have discovered.

9 Oct 2017

Your grandma’s guide to grass: Calif. rolls out website to cut through cannabis haze

Every day, Anna Denny encounters people who know their way around a joint. Denny owns Elevated 916, a smoke shop in north Sacramento that sells tobacco products and smoking accessories. But many of her customers don't limit their smoking to tobacco.

9 Oct 2017

Powerful clot-busting drugs found safe for treating stroke patients with dementia

Stroke patients with dementia treated with intravenous thrombolysis using powerful clot-busting drugs are at no higher risk of brain hemorrhage or death than other patients receiving the same treatment, a study from Karolinska Institutet published in the journal Neurology reports.

9 Oct 2017

Patients with documented penicillin allergy more likely to develop surgical site infections, study finds

A study by Massachusetts General Hospital investigators found that surgical patients believed to be allergic to penicillin were significantly more likely to develop surgical site infections than were patients with no documented allergy, a difference totally attributable to the alternative antibiotics used to prevent such infections.

9 Oct 2017

University of Akron researcher awarded NSF grant to study bone remodeling

Osteoporosis is a disease categorized by brittle bones and increased risk of fracture. Individuals with osteoporosis, and diseases like it, have access to a number of treatments but no permanent solution.

9 Oct 2017

Yale scientists unravel molecular mechanism of breast cancer risk gene

More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.

9 Oct 2017

WHO delivers 1.2 million doses of antibiotics to prevent, treat plague in Madagascar

WHO has delivered nearly 1.2 million doses of antibiotics and released US$1.5 million dollars in emergency funds to fight plague in Madagascar

9 Oct 2017

FDA approves new treatment option for patients with moderate to severe central sleep apnea

The U.S. Food and Drug Administration today approved a new treatment option for patients who have been diagnosed with moderate to severe central sleep apnea.

9 Oct 2017

Scientists discover how ZATT protein fixes DNA damage caused by cancer treatment

An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein cross-link.

6 Oct 2017

Genetic signature within prostate cancer cells can predict metastatic tumors

Many prostate cancers, which generally are diagnosed in older men, are "indolent," slow-growing tumors that aren't destined to be fatal. But some tumors are prone to becoming aggressive and spreading beyond the prostate, making them difficult to treat and life-threatening.

6 Oct 2017

Drugs News and Research

Abnormalities of blood vessels in the brain may play major role in development of schizophrenia

Common acid reflux drugs linked to progression of chronic liver disease

Human minibrains expose psychedelic drug effects, study reveals

New insights into rare-among-rare genetic bone disorder

Improving synchronization of brain waves enhances learning and self-control

Medicare plans place few restrictions on coverage of prescription opioids, Yale study finds

Cells lining blood vessels in the lungs exposed to bacterial toxins don’t die easy, UIC study says

New law challenges ‘evils’ of pharma profits, California governor claims

Shifting toward novel pricing models that closely link drug's price to its value

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Your grandma’s guide to grass: Calif. rolls out website to cut through cannabis haze

Powerful clot-busting drugs found safe for treating stroke patients with dementia

Patients with documented penicillin allergy more likely to develop surgical site infections, study finds

University of Akron researcher awarded NSF grant to study bone remodeling

Yale scientists unravel molecular mechanism of breast cancer risk gene

WHO delivers 1.2 million doses of antibiotics to prevent, treat plague in Madagascar

FDA approves new treatment option for patients with moderate to severe central sleep apnea

Scientists discover how ZATT protein fixes DNA damage caused by cancer treatment

Genetic signature within prostate cancer cells can predict metastatic tumors

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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