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Novel anti-inflammatory therapy protects lungs from runaway inflammation

A novel anti-inflammatory therapy designed by Vanderbilt University Medical Center investigators prevents acute lung injury in mice exposed to an inflammation-causing toxin, the researchers report in the journal Molecular Therapy.

11 Mar 2009

New perspective on what part of the brain controls fear

Mice lose their fear of territorial rivals when a tiny piece of their brain is neutralized, a new study reports.

10 Mar 2009

Discovery of new gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH), MIT, the Broad Institute, King's College London (KCL) and other institutions has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

5 Mar 2009

Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols

Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols.

3 Mar 2009

Researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

26 Feb 2009

New gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King's College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

26 Feb 2009

A second MND gene mutation in one year signifies rapid research progress

A collaborative research project involving Professor Christopher Shaw of the Institute of Psychiatry, King's College London (KCL), Dr Tom Kwiatkowski at Massachusetts General Hospital (MGH) and Professor Robert H Brown at University of Massachusetts, has revealed that mutations in a gene called FUS (fused in sarcoma) cause familial Motor Neuron Disease (also known as Amyotrophic Lateral Sclerosis).

26 Feb 2009

Aching back? cholesterol drug Lovastatin might help

Back pain, a hallmark of degenerative disc disease, sends millions of people to their doctor. In fact, more than 80 percent of patients who undergo spine surgery do so because of disc degeneration.

22 Feb 2009

Artificial cells, simple model for complex structure

A simple, chemical materials model may lead to a better understanding of the structure and organization of the cell according to a Penn State researcher.

16 Feb 2009

Molecular machine turns packaged messenger RNA into a linear transcript

For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane.

11 Feb 2009

ViroPharma reports results of trial for Maribavir in bone marrow transplant patients

ViroPharma Incorporated has announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

10 Feb 2009

Scientists deconstruct cell division

The last step of the cell cycle is the brief but spectacularly dynamic and complicated mitosis phase, which leads to the duplication of one mother cell into two daughter cells.

8 Feb 2009

Animal eggs no source for embryonic stem cells

Stem cell researchers in the U.S. say that eggs from cows, rabbits and other animals are not a good source for creating embryonic stem cells.

3 Feb 2009

New technology rapidly detects tumor response to chemotherapy

New technology developed by Duke University bioengineers can help clinicians more precisely detect whether specific cancer drugs are working, and should give basic researchers a powerful new tool to better understand the underlying mechanisms of cancer development.

2 Feb 2009

New imaging technique distinguishes breast cancer cells from normal cells

A team of researchers at the University of California, San Diego (UCSD) and the Moores UCSD Cancer Center have developed a rapid, automated image screening process to distinguish breast cancer cells from normal cells.

2 Feb 2009

Smallest quantum dots ever created

Single atom quantum dots created by researchers at Canada's National Institute for Nanotechnology and the University of Alberta make possible a new level of control over individual electrons, a development that suddenly brings quantum dot-based devices within reach.

29 Jan 2009

Leaky membranes: Another sign of old age

As parts of us age, even the membrane bound nuclei , which house the genetic instructions for life that are "written" in our DNA, begin to show considerable wear and tear, suggests a new report in the January 23rd issue of the journal Cell, a Cell Press publication.

23 Jan 2009

Large DNA stretches, not single genes, shut off as cells mature

Experiments at Johns Hopkins have found that the gradual maturing of embryonic cells into cells as varied as brain, liver and immune system cells is apparently due to the shut off of several genes at once rather than in individual smatterings as previous studies have implied.

19 Jan 2009

Mutant host cell protein sequesters critical HIV-1 element

Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis.

19 Jan 2009

How the sensory organs of bacteria function

Bacteria can occur almost anywhere on earth and exist under the most varying conditions. If these tiny, microscopic organisms are to survive in these environments, they need to be able to rapidly detect changes in their surroundings and react to them.

19 Jan 2009