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Scientists identify key driver in BRAF inhibitor resistant melanoma

Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body.

2 Sep 2020

Misfiring brain cells may create swallowing difficulties in children with neurodevelopmental disorders

Misfiring brain cells that control key parts of the mouth and tongue may be creating swallowing difficulties in children with neurodevelopmental disorders, according to neuroscientists with Virginia Tech and George Washington University.

2 Sep 2020

Scientists find promising drug candidates for treatment of motor neurone disease

Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.

1 Sep 2020

Cancer cells reshape, destroy or integrate into blood vessels to spread

In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.

1 Sep 2020

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

A research group from Slovenia, Switzerland, and Germany shows how nanoscaffolded assemblies may neutralize interaction between the SARS-CoV-2 spike protein and cell receptor, providing adequate protection in a surrogate infection assay and warranting the advance of such platforms in the pursuit for the effective vaccine.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

Alarmins are the 'gold' in breast milk

Breast milk strengthens a child's immune system, supporting the intestinal flora. These facts are common knowledge.

28 Aug 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

A new COVID-19 mouse model developed at the University of North Carolina at Chapel Hill captures many of the features of human disease and has helped advance a COVID-19 vaccine candidate to clinical trial.

27 Aug 2020

First lethal mouse model of SARS-CoV-2 developed

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

27 Aug 2020

New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

Study: Blocking nerve signals to the pancreas could stop patients from developing type 1 diabetes

Your pancreas is a little sweet potato-shaped organ that sits snug behind your stomach. The pancreas is studded with islets, the cell clusters that house insulin-producing beta cells.

27 Aug 2020

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

People who consume frozen microbiome capsules derived from their own feces when dieting may limit their weight regain, according to a new study published in Gastroenterology, conducted by a team of researchers led by researchers at Ben-Gurion University of the Negev.

26 Aug 2020

Mouse Model News and Research

Scientists identify key driver in BRAF inhibitor resistant melanoma

Misfiring brain cells may create swallowing difficulties in children with neurodevelopmental disorders

Scientists find promising drug candidates for treatment of motor neurone disease

Cancer cells reshape, destroy or integrate into blood vessels to spread

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Alarmins are the 'gold' in breast milk

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

First lethal mouse model of SARS-CoV-2 developed

New approach to combination drug design could be applied to disease therapies beyond diabetes

Study: Blocking nerve signals to the pancreas could stop patients from developing type 1 diabetes

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

New approach provides a roadmap for linking neurological and locomotor deficits

Researchers identify potential drug target for curtailing cancer metastasis

Researchers find a new way to slow colon cancer metastasis

Study reveals a promising method for treating multiple sclerosis

A metabolic enzyme shows great potential as target for immunotherapies

Air pollution may play a role in development of cardiometabolic diseases, shows study

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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