Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Rexahn reports initial results from Supinoxin Phase I trial in patients with solid cancer tumors

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company announced today initial data for the Phase I dose-escalation clinical trial of SupinoxinTM (RX-5902) initiated in August 2013. This trial was designed to study safety and efficacy in patients with solid cancer tumors.

11 Mar 2014

High antibody affinity identifies type 1 diabetes

LADA (latent autoimmune diabetes in adults) is a form of type 1 diabetes in adulthood. Like the childhood form, the insulin-producing beta cells of the pancreas are destroyed by the body's own immune system.

11 Mar 2014

Novel treatment strategy during transplantation surgery could spare patients from rejection

Organ-transplant recipients often reject donated organs, but a new, two-pronged strategy developed by UC San Francisco researchers to specifically weaken immune responses that target transplanted tissue has shown promise in controlled experiments on mice.

11 Mar 2014

Skin cancer may increase risk of other cancers later in life

Australian author on the paper, Professor Rodney Sinclair, Professor of Medicine at the University of Melbourne and Director of Dermatology at Epworth HealthCare said that the risk decreased significantly with increasing age, but it remains higher compared with individuals who have never had NMSC.

10 Mar 2014

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

Kamada Ltd. (NASDAQ:KMDA) (TASE:KMDA), a plasma-derived protein therapeutics company focused on orphan indications, announces the initiation of a Phase 2/3 clinical trial of Glassia®, the Company's proprietary human Alpha-1 Antitrypsin (AAT), to treat newly diagnosed pediatric patients with type 1 diabetes (T1D).

5 Mar 2014

AAA gets orphan drug designation status for radiopharmaceutical, Gallium-68 DOTATATE

Advanced Accelerator Applications (AAA), a fast growing international player in Molecular Nuclear Medicine (MNM), announced today that they have received orphan drug designation status for their radiopharmaceutical, Gallium-68 DOTATATE.

4 Mar 2014

New theory on the causation of type 2 diabetes

At 85, Nobel laureate James D. Watson, the co-discoverer of the double-helix structure of DNA, continues to advance intriguing scientific ideas. His latest, a hypothesis on the causation of type 2 diabetes, is to appear 7 pm Thursday US time in the online pages of The Lancet, the prestigious British medical journal.

4 Mar 2014

Researchers identify mutations in gene that can reduce risk of developing type 2 diabetes

An international team led by researchers at the Broad Institute and Massachusetts General Hospital (MGH) has identified mutations in a gene that can reduce the risk of developing type 2 diabetes, even in people who have risk factors such as obesity and old age.

3 Mar 2014

Researchers find link between acute pancreatitis and pancreatic cancer

In a study published in Clinical Gastroenterology and Hepatology, Saint Louis University researchers have found a link between acute pancreatitis (inflammation of the pancreas) and pancreatic cancer, a finding which may eventually lead to some pancreatic cancers being detected earlier.

27 Feb 2014

Study highlights the importance of personalized medicine for treating cancer

If a driver is traveling to New York City, I-95 might be their route of choice. But they could also take I-78, I-87 or any number of alternate routes. Most cancers begin similarly, with many possible routes to the same disease. A new study found evidence that assessing the route to cancer on a case-by-case basis might make more sense than basing a patient's cancer treatment on commonly disrupted genes and pathways.

26 Feb 2014

Study identifies enzyme with key role in precancerous lesions

Cancer of the pancreas is usually not detected until it's too late to cure. But precursor lesions that form in the pancreas and its ducts can signal the disease before it strikes, and when caught early enough, they can be prevented from progressing to become cancer.

26 Feb 2014

Study highlights novel reprogramming method that offers new hope for treating liver failure

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature-a crucial prerequisite for life-saving therapies-has proven far more difficult.

24 Feb 2014

Chewable drug candidate BTI320 can potentially prevent added sugar intake

It's official: sugar is not so sweet—for our health, that is. The new study "Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults," published in JAMA Internal Medicine, examines the intake of "added sugars," and the results suggest that sugar is now an independent risk factor for heart disease and other chronic diseases.

21 Feb 2014

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

UC Irvine researchers have found a specific genetic flaw that is connected to sudden death due to heart arrhythmia - a leading cause of mortality for adults around the world.

18 Feb 2014

New theory for how stem cells decide whether to become liver or pancreatic cells

Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in inflammation and pain.

14 Feb 2014

Researchers discover highly accurate, noninvasive test to identify benign pancreatic cysts

Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts, which could spare patients years of nerve-racking trips to the doctor or potentially dangerous surgery.

12 Feb 2014

Surgeons now use minimally invasive robotic surgical system for Whipple procedure

The Whipple procedure, used to remove tumors from pancreatic cancer patients, is one of surgery's most extensive and challenging operations.

11 Feb 2014

Gladstone-led study represents important step towards cure for type 1 diabetes

A cure for type 1 diabetes has long eluded even the top experts. Not because they do not know what must be done-but because the tools did not exist to do it. But now scientists at the Gladstone Institutes, harnessing the power of regenerative medicine, have developed a technique in animal models that could replenish the very cells destroyed by the disease.

7 Feb 2014

Children newly diagnosed with Crohn's disease may benefit from biologic drugs

Children newly diagnosed with Crohn's disease may benefit from early treatment with the biologic drugs known as anti-TNF-α agents, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

3 Feb 2014

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans, and MRIs, ultrasound has seen limited use in cancer treatment due to clarity and resolution issues.

29 Jan 2014

Pancreas News and Research

Further Reading

Rexahn reports initial results from Supinoxin Phase I trial in patients with solid cancer tumors

High antibody affinity identifies type 1 diabetes

Novel treatment strategy during transplantation surgery could spare patients from rejection

Skin cancer may increase risk of other cancers later in life

Kamada initiates Phase 2/3 clinical trial of Glassia to treat pediatric patients with T1D

AAA gets orphan drug designation status for radiopharmaceutical, Gallium-68 DOTATATE

New theory on the causation of type 2 diabetes

Researchers identify mutations in gene that can reduce risk of developing type 2 diabetes

Researchers find link between acute pancreatitis and pancreatic cancer

Study highlights the importance of personalized medicine for treating cancer

Study identifies enzyme with key role in precancerous lesions

Study highlights novel reprogramming method that offers new hope for treating liver failure

Chewable drug candidate BTI320 can potentially prevent added sugar intake

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

New theory for how stem cells decide whether to become liver or pancreatic cells

Researchers discover highly accurate, noninvasive test to identify benign pancreatic cysts

Surgeons now use minimally invasive robotic surgical system for Whipple procedure

Gladstone-led study represents important step towards cure for type 1 diabetes

Children newly diagnosed with Crohn's disease may benefit from biologic drugs

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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