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New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Researchers at the Faculty of Medicine, University of Helsinki, make an unexpected and vital contribution to an international collaborative effort in Parkinson's disease research.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Study identifies novel missense mutation affecting YARS causes multisystem disease

Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

New AI technology can potentially reduce bottlenecks in drug research

Researchers at the University of Waterloo have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests.

7 Nov 2018

New synthetic compound based on brain hormone holds promise for cancer treatment

A lab team led by Nobel Prize winner Dr. Andrew Schally at the Miami Veterans Affairs Healthcare System and the University of Miami showed that a synthetic compound based on a brain hormone spurred the growth of cancer cells in Petri dishes but enigmatically had the opposite effect in mice.

6 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

To expand the understanding and explanation of Alzheimer's disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio College of Sciences to establish the Oskar Fischer Project.

5 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Study of two indigenous populations reveals how diet affects health and well-being

From the standpoint of heart health, the Tsimane are a model group. A population indigenous to the Bolivian Amazon, the Tsimane demonstrate next to no heart disease.

3 Nov 2018

Molecular virologist uses basic science to fight influenza

Molecular virologist Chad Petit, Ph.D., uses basic science to fight influenza -- through experiments at the atomic level.

3 Nov 2018

Researchers focus on whether eating enough protein can help delay disability in older adults

To live successfully and independently, older adults need to be able to manage two different levels of life skills: basic daily care and basic housekeeping activities.

2 Nov 2018

UCV researchers discover the influence of exosomes on age-related macular degeneration

Researchers of the Neurobiology and Neurophysiology team of the Medicine Faculty at Valencia Catholic University, headed by Jorge Bacia, have discovered that exosomes - microscopic extracellular vesicles that are released by all cells - from the retinal pigment epithelium lead to cases of neovascularization, a finding which could be closely related to similar processes in age-related macular degeneration.

2 Nov 2018

New study upends conventional theories about fluid nature of cell membranes

If you want to understand how the cell membrane works, Adam Cohen says, look no further than your kitchen. Cohen, a Professor of Chemistry and Chemical Biology and of Physics, is the lead author of a new study that upends the conventional theories about the fluid nature of cell membranes and how they react to tension.

2 Nov 2018

Protein C News and Research

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Study identifies novel missense mutation affecting YARS causes multisystem disease

Scientists discover new details about UHRF1 protein

New AI technology can potentially reduce bottlenecks in drug research

New synthetic compound based on brain hormone holds promise for cancer treatment

Researchers identify pathway to resolve allergic asthma

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

New research explains how large virus shells are formed

Study of two indigenous populations reveals how diet affects health and well-being

Molecular virologist uses basic science to fight influenza

Researchers focus on whether eating enough protein can help delay disability in older adults

UCV researchers discover the influence of exosomes on age-related macular degeneration

New study upends conventional theories about fluid nature of cell membranes

New way of identifying potential cancer drugs could streamline development of therapies

New form of therapy may stop or reverse progressive vision loss

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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