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Minimally invasive valve replacement appears to provide durable remedy for people with heart disease

A minimally invasive procedure used to replace heart valves without open heart surgery appears to provide a durable remedy for people with a life-threatening form of heart disease in which the aortic valve opening narrows, diminishing blood flow.

27 Sep 2017

Plant substance shows inhibitory effects on cancer stem cells

The plant Ambrosia arborescens grows at a high elevation in large parts of South America, and is traditionally used as a medicinal plant. The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

27 Sep 2017

Researchers explore what happens during break down of nerve cells

A stroke is just one example of a condition when communication between nerve cells breaks down. Micro-failures in brain functioning also occur in conditions such as depression and dementia. In most cases, the lost capacity will return after a while.

27 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Right after Trump blamed high drug prices on campaign cash, drugmakers gave more

"The cost of medicine in this country is outrageous," President Donald Trump said at a rally in Louisville, Ky., two months after his inauguration. He went on about how identical pills have vastly lower price tags in Europe.

27 Sep 2017

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

A research team led by DGIST Professor Moon Cheil at the Department of Brain and Cognitive Sciences has identified the reason why the patients with the early stage of Alzheimer's fail to smell.

27 Sep 2017

Adding, removing water from a stem cell can determine its role as bone or fat

Adding or removing water from a stem cell can change the destiny of the cell, researchers have discovered in a new study published in the Proceedings of the National Academy of Sciences.

27 Sep 2017

Scientists gain insight into how Ebola virus uses the body's defenses to speed up infection

Scientists from The University of Texas Medical Branch at Galveston have gained new insight into how the Ebola virus uses the body's natural defenses to speed the rate of infection and unleash its lethal disease, according to a new report in mBio.

26 Sep 2017

Emergency departments write shorter duration and smaller-dose opioid prescriptions, study shows

Opioid prescriptions from the emergency department are written for a shorter duration and smaller dose than those written elsewhere, shows new research led by Mayo Clinic.

26 Sep 2017

Researchers will measure and examine how ‘resilience’ may lead to better HIV-related outcomes

With studies showing that African Americans living with HIV disproportionately struggle to remain in care and maintain suppressed HIV RNA levels, a team of public health researchers will look for solutions in a new way: They will systematically and rigorously identify the resources that successful patients draw upon to overcome the pervasive pitfalls that hinder others.

26 Sep 2017

Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

Antibiotics reduce risk of recurrent staph infections in children, research shows

The overuse of antibiotics has left some doctors questioning whether to give such drugs to children diagnosed with uncomplicated staph infections. Such infections often occur on the skin and look like a pus-filled bug bite.

26 Sep 2017

Study finds no evidence of auditory nerve injury after recreational noise exposure

Exposure to loud noises during common recreational activities is widely cited as a cause of "hidden hearing loss." A new study of young adults, however, finds that while hearing is temporarily affected after attending a loud event, there is no evidence of auditory nerve injury or permanent hearing difficulties.

26 Sep 2017

New approaches to treat aggressive NUT midline carcinoma

Precision medicine, which custom-tailors therapies to the needs of individual patients, is becoming more and more important in cancer therapy. Today, molecular-biological diagnostics can precisely identify alterations in tumor cells.

26 Sep 2017

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce the National Institute on Drug Abuse at the National Institutes of Health has awarded Nicholas Cosford, Ph.D., a three-year, $10.8 million grant to pursue the preclinical development of a new class of medicine to treat substance use disorders.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Review finds no increased cancer risk for people taking oral diabetes medication

People taking a new oral medication for Type 2 diabetes can breathe a sigh of relief concerning suspicions they might be at an increased risk for many types of cancer, according to Indiana University researchers.

26 Sep 2017

Advanced technique could pave way for cascade of new steroidal therapeutics

Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process, published in the journal Nature Chemistry, facilitates access to rare, mirror-image isomers of naturally occurring steroid structures.

26 Sep 2017

Drugs News and Research

Minimally invasive valve replacement appears to provide durable remedy for people with heart disease

Plant substance shows inhibitory effects on cancer stem cells

Researchers explore what happens during break down of nerve cells

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Right after Trump blamed high drug prices on campaign cash, drugmakers gave more

Researchers reveal reason for olfactory dysfunction in initial stage of Alzheimer's disease

Adding, removing water from a stem cell can determine its role as bone or fat

Scientists gain insight into how Ebola virus uses the body's defenses to speed up infection

Emergency departments write shorter duration and smaller-dose opioid prescriptions, study shows

Researchers will measure and examine how ‘resilience’ may lead to better HIV-related outcomes

Drug combination produces synergistic effect against growth of triple-negative breast cancer

MIT study sheds light on flu viruses' rapid evolution

Antibiotics reduce risk of recurrent staph infections in children, research shows

Study finds no evidence of auditory nerve injury after recreational noise exposure

New approaches to treat aggressive NUT midline carcinoma

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Review finds no increased cancer risk for people taking oral diabetes medication

Advanced technique could pave way for cascade of new steroidal therapeutics

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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