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Rare pattern of gut microbes in newborns linked to higher risk of later allergies and asthma

The microbes living in a baby's gut during its first month of life may directly impact the developing immune system, leading to a higher risk of allergies and asthma later in childhood, according to a study by researchers at UC San Francisco and the Henry Ford Health System in Detroit.

12 Sep 2016

Researchers find innovative and cost-effective ways to remove PFAS from water supply

Elevated levels of perfluoroalkyl substances (PFASs) in drinking water can persist in water supplies for long periods and present an important health risk for millions of Americans, from hormone suppression to potentially cancer.

9 Sep 2016

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.

9 Sep 2016

Study opens door to new class of therapies for Ras-dependent cancers

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies.

9 Sep 2016

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

9 Sep 2016

New treatment reduces activity of Huntington's disease gene for several months in mice

A single injection of a new treatment has reduced the activity of the gene responsible for Huntington's disease for several months in a trial in mice.

9 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Scientists discover potential new genetic causes for intellectual disability

An international group of researchers has for the first time identified a set of 30 inherited recessive genes that play a role in intellectual disability (ID), a neurodevelopmental disorder that, according to the Centers for Disease Control, affects as many as 213 million people around the world.

9 Sep 2016

Fruit flies hold clues to how cancerous tumors get started

A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors.

9 Sep 2016

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

A new study by the Translational Genomics Research Institute and Northern Arizona University used deep DNA sequencing methods to generate the anthrax genome sequence from the victims of the 1979 anthrax outbreak in Sverdlovsk, Russia, when it was part of the USSR.

9 Sep 2016

Medical errors may be prevented by shifting to integrative model of healthcare

Medical errors are the third leading cause of death in the U.S. according to a published estimate, but many could be prevented with a shift in the medical industry from a production-driven to an integrative model of healthcare.

9 Sep 2016

Study points out critical need for new interventions to prevent suicide among SGM youth

Homosexual, bisexual, and transgender youth tend to have a higher risk for suicide-related thoughts and behaviors, but research on interventions to prevent suicide among sexual and gender minority (SGM) youth has been limited.

9 Sep 2016

MIT biologists unravel lncRNA structure-to-function relationships

Several years ago, biologists discovered a new type of genetic material known as long noncoding RNA. This RNA does not code for proteins and is copied from sections of the genome once believed to be "junk DNA."

9 Sep 2016

Interactions between rare and common genetic variants may contribute to craniosynostosis

During the first year of life, the human brain doubles in size, and continues growing through adolescence.

8 Sep 2016

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes.

8 Sep 2016

Clinical trial to examine effectiveness of diabetes drug to slow or stop progression of Parkinson's

Type II diabetes and Parkinson's disease may not appear to have much in common but a look below the surface reveals important molecular similarities that provide a potential target for fighting Parkinson's.

8 Sep 2016

Acute COPD exacerbations linked to long-term decline in lung function

Acute exacerbations of chronic obstructive pulmonary disease, or COPD, are associated with significant long-term lung function loss, according to research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

8 Sep 2016

IWGAV establishes strategic recommendations for validating antibody specificity

The International Working Group on Antibody Validation, an independent group of international scientists with diverse research interests in the field of protein biology, today announced the publication of initial strategies developed to address a critical unmet need for antibody specificity, functionality and reproducibility in the September online issue of Nature Methods.

8 Sep 2016

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine.

8 Sep 2016

Researchers unlock genetic code that disrupts response to breast cancer therapy

Scientists may have unlocked the genetic code that determines why many patients with estrogen receptor-positive breast cancer fail to respond to the widely used drug tamoxifen.

7 Sep 2016

Genetic News and Research

Rare pattern of gut microbes in newborns linked to higher risk of later allergies and asthma

Researchers find innovative and cost-effective ways to remove PFAS from water supply

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Study opens door to new class of therapies for Ras-dependent cancers

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

New treatment reduces activity of Huntington's disease gene for several months in mice

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists discover potential new genetic causes for intellectual disability

Fruit flies hold clues to how cancerous tumors get started

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

Medical errors may be prevented by shifting to integrative model of healthcare

Study points out critical need for new interventions to prevent suicide among SGM youth

MIT biologists unravel lncRNA structure-to-function relationships

Interactions between rare and common genetic variants may contribute to craniosynostosis

Exposure to air pollution at place of residence could be risk factor for type 2 diabetes

Clinical trial to examine effectiveness of diabetes drug to slow or stop progression of Parkinson's

Acute COPD exacerbations linked to long-term decline in lung function

IWGAV establishes strategic recommendations for validating antibody specificity

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

Researchers unlock genetic code that disrupts response to breast cancer therapy

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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