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Study recommends revision of current guidelines for assessing orthostatic hypotension

A new study led by Johns Hopkins researchers suggests that testing for the presence of orthostatic hypotension, a form of low blood pressure, be performed within one minute of standing after a person has been lying down.

31 Jul 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Scientists discover ways to increase efficiency in neurofeedback training paradigm

Researchers from the HSE Centre for Cognition & Decision Making and the Control of Complex Systems Laboratory (Institute of Problems of Mechanical Engineering, Russian Academy of Sciences) have conducted a series of experiments to uncover what a person actually controls when they are tasked with independently affecting the activity of their own brain.

29 Jul 2017

Hunger-controlling brain cells offer potential targets for new drugs to treat obesity

Is the solution to the obesity epidemic all in our heads? A study by researchers at The Rockefeller University suggests that it might be.

28 Jul 2017

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has reached the halfway point for enrollment and treatment.

28 Jul 2017

DKFZ scientists reveal how cancer cells suppress immune system to spread and multiply

The degenerated cells cause an inflammatory reaction and influence other blood cells with it so much, that the immune system is suppressed.

28 Jul 2017

Skin transplant surgery has long-term benefit for restoring pigmentation caused by vitiligo

A Henry Ford Hospital study has shown that skin transplant surgery has long-term benefit for restoring skin pigmentation caused by the skin disease vitiligo.

27 Jul 2017

Scientists notice shift in transmission mechanism of HEV infections

Hepatitis E gets little press compared to its better-known cousins A, B, and C, but Stellenbosch University virologists say we should wake up to how transmission of this virus is changing. World Hepatitis Day is commemorated on 28 July.

27 Jul 2017

Stem cells in the brain found to influence aging in mice

A study conducted by a team of researchers led by Dongsheng Cai at the Albert Einstein College of Medicine, New York, finds that injecting extra stem cells into the hypothalamus in the brain of mice slows down the aging process.

27 Jul 2017

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

27 Jul 2017

Robotic training method improves posture and walking in children with cerebral palsy

In the U.S., 3.6 out of 1000 school-aged children are diagnosed with cerebral palsy (CP). Their symptoms include abnormal gait patterns which results in joint degeneration over time.

27 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

Genetic test to predict IBD severity in children

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract with abdominal pain and diarrhea being the most common symptoms. It can be challenging to diagnose as gastrointestinal complaints mimicking IBD are common.

26 Jul 2017

Study offers potential new strategy for use of retinoids against some breast cancers

Estrogen-positive breast cancers are often treated with anti-estrogen therapies. But about half of these cancers contain a subpopulation of cells marked by the protein cytokeratin 5 (CK5), which resists treatment -- and breast cancers with higher CK5 expression have poorer prognosis.

26 Jul 2017

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.

25 Jul 2017

Men with hepatitis B more likely to develop severe liver disease despite lifestyle choices

Why men with hepatitis B remain more than twice as likely to develop severe liver disease than women remains a mystery, even after a study led by a recent Drexel University graduate took lifestyle choices and environments into account.

25 Jul 2017

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used.

25 Jul 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Study determines safest temperature and duration for body-cooling of newborns

After more than 20 years of research on the best treatment for full-term infants affected by oxygen deprivation during the birthing process, Seetha Shankaran, M.D., neonatologist at DMC's Children's Hospital of Michigan and Hutzel Women's Hospital, served as the lead investigator in a definitive Journal of the American Medical Association study that documented the safest depth and duration of body-cooling to minimize injury from hypoxic ischemic encephalopathy (HIE) in newborns.

25 Jul 2017

Cocktail of drugs for HIV patients with advanced immunosuppression reduced deaths by 27%, study shows

A study published in the New England Journal of Medicine on 20th July 2017 suggests that a cocktail of drugs, if provided at the beginning of the HIV therapy, can save over 10,000 lives per year. HIV, which is often diagnosed late, leaves people vulnerable to other diseases by ravaging the immune system.

25 Jul 2017

Therapy News and Research

Study recommends revision of current guidelines for assessing orthostatic hypotension

Bringing highly potent cell therapy products to market

Scientists discover ways to increase efficiency in neurofeedback training paradigm

Hunger-controlling brain cells offer potential targets for new drugs to treat obesity

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

DKFZ scientists reveal how cancer cells suppress immune system to spread and multiply

Skin transplant surgery has long-term benefit for restoring pigmentation caused by vitiligo

Scientists notice shift in transmission mechanism of HEV infections

Stem cells in the brain found to influence aging in mice

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

Robotic training method improves posture and walking in children with cerebral palsy

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

Genetic test to predict IBD severity in children

Study offers potential new strategy for use of retinoids against some breast cancers

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

Men with hepatitis B more likely to develop severe liver disease despite lifestyle choices

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Study determines safest temperature and duration for body-cooling of newborns

Cocktail of drugs for HIV patients with advanced immunosuppression reduced deaths by 27%, study shows

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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