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New method to 'sneak' biological drugs into brain cells offers hope to cure neurological diseases

The treatment of brain diseases is on the verge of a breakthrough. Researchers from Aalborg University are developing a new method that 'smuggles' medicine past the brain's defense systems, giving hope that diseases such as Alzheimer's can one day be cured.

12 Sep 2017

$New medication shows potential to reduce fracture risk in women with osteoporosis$

New medication shows potential to reduce fracture risk in women with osteoporosis

A new drug that boosts bone formation has been shown to reduce the risk of fracture in women with osteoporosis when compared to one of the most commonly used osteoporosis medications.

12 Sep 2017

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Scientists at The Scripps Research Institute have found a new approach to the "reprogramming" of ordinary adult cells into stem cells.

12 Sep 2017

VUMC and Bayer agree on strategic research alliance to develop new therapies for kidney diseases

Vanderbilt University Medical Center and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development.

12 Sep 2017

Study findings may have critical implications to boost efficacy of T cell-based therapies

T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy.

11 Sep 2017

TSRI scientists confirm that quality control steps exist to protect production of proteins

The devil, as always, is in the details. The production of proteins is a complex process, made up of a series of smaller intricate biochemical steps that succeeds because of an equally complex number of quality controls. Without them, the process would irreparably break down and diseases like cancer would run rampant.

11 Sep 2017

Children with asthma more likely to be prescribed unnecessary antibiotics, study finds

Children with asthma are more likely to be prescribed antibiotics even though there is no evidence that they need them any more than children without asthma, according to research to be presented at the European Respiratory Society International Congress 2017.

11 Sep 2017

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Combination immunotherapy as second or third line treatment extends overall survival to at least 15 months in patients with pleural malignant mesothelioma, according to late-breaking results from the MAPS2 trial presented today at the ESMO 2017 Congress in Madrid.

11 Sep 2017

Drugs used for treatment of high cholesterol may benefit patients with cirrhosis

Statins used for the treatment of high cholesterol may have other beneficial effects, but there has been reluctance to prescribe them to patients with liver disease because of concerns that they may cause abnormal liver enzyme levels in the blood.

11 Sep 2017

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Two new treatments may benefit patients with high risk prostate cancer, trial shows

Patients with high risk prostate cancer starting long-term hormone therapy may benefit from two new treatments, according to late-breaking results from the STAMPEDE trial presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

New approaches to prevent or treat antipsychotic-induced supersensitivity psychosis

In the current issue of Psychotherapy and Psychosomatic, professor Guy Chouinard, one of the most important psychopharmacologists, provides a synthesis of the data that are concerned with neglected side effects of commonly used psychotropic drugs.

8 Sep 2017

Neuroscientists discover new signaling pathway that could be good drug target to fight chronic pain

Researchers have discovered a new pain-signaling pathway in nerve cells that eventually could make a good target for new drugs to fight chronic pain.

8 Sep 2017

Scientists find new strategy for overcoming resistance to drugs in lung cancer patients

Research at the University of Southern Denmark has revealed that a new combination of clinically tested drugs inhibits the growth of tumors, thereby potentially improving patients' survival.

8 Sep 2017

Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

A new study indicates that direct-acting antiviral therapy is safe and effective in patients with chronic kidney disease (CKD) and Hepatitis C virus (HCV) infection.

8 Sep 2017

Combination treatment provides positive results for people with advanced melanoma

In a two-year UCLA-led study, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC.

8 Sep 2017

Eli Lilly to lay off 8.5 percent of employees in bid to cut costs

Eli Lilly and Company announced yesterday that they have decided to lay off around 8.5 percent of their employees. The company was on its way to develop two potential major drugs over the past year but set backs have led to major financial losses, leading to this decision.

7 Sep 2017

Tulane researchers move closer to improving treatment for chronic depression

In a new study published in the journal Cell Reports, researchers associated with the Tulane Brain Institute say they have moved a step closer to improving treatment for chronic depression.

7 Sep 2017

CWRU professor wins $3.9 million NIH grant to identify countermeasures against chemical hazards

Kurt Lu, MD, assistant professor of dermatology at Case Western Reserve University School of Medicine, has received a five year, $3.9 million grant from the National Institutes of Health to expand countermeasures against chemical threats, including mustard gas and mustard-related compounds.

7 Sep 2017

Drugs News and Research

New method to 'sneak' biological drugs into brain cells offers hope to cure neurological diseases

New medication shows potential to reduce fracture risk in women with osteoporosis

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

VUMC and Bayer agree on strategic research alliance to develop new therapies for kidney diseases

Study findings may have critical implications to boost efficacy of T cell-based therapies

TSRI scientists confirm that quality control steps exist to protect production of proteins

Children with asthma more likely to be prescribed unnecessary antibiotics, study finds

Combination immunotherapy as second or third line treatment of mesothelioma shows promising results

Drugs used for treatment of high cholesterol may benefit patients with cirrhosis

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Two new treatments may benefit patients with high risk prostate cancer, trial shows

New approaches to prevent or treat antipsychotic-induced supersensitivity psychosis

Neuroscientists discover new signaling pathway that could be good drug target to fight chronic pain

Scientists find new strategy for overcoming resistance to drugs in lung cancer patients

Direct-acting antiviral therapy found to be safe, effective in patients with CKD and HCV infection

Combination treatment provides positive results for people with advanced melanoma

Eli Lilly to lay off 8.5 percent of employees in bid to cut costs

Tulane researchers move closer to improving treatment for chronic depression

CWRU professor wins $3.9 million NIH grant to identify countermeasures against chemical hazards

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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