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Aspen Dental to open five new locations in Arkansas in 2015

Access to dental care in Arkansas is about to get a healthy boost with the addition of five new Aspen Dental–branded practices, the first of which will open in Searcy and Jonesboro on Thursday, April 9.

31 Mar 2015

Roche launches new protein melting application for real-time PCR LightCycler 1536 instrument

Roche announced today the introduction of a new protein melting application for its high-throughput, real-time PCR LightCycler 1536 instrument. The fully automated platform now allows life science researchers to perform thermal shift assays (TSAs) in 1536-well applications quickly and consistently.

From Roche Sequencing and Life Science 31 Mar 2015

Researchers report correlative links between family income, brain structure in children

Characterizing associations between socioeconomic factors and children's brain development, a team including investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family income were strongest in the lowest end of the economic range - suggesting that interventional policies aimed at these children may have the largest societal impact.

31 Mar 2015

Drug-resistant E. coli outbreak linked to contaminated endoscopes in Washington state hospital

An outbreak of a novel Escherichia coli (E. coli) strain resistant to antibiotics has been linked to contaminated endoscopes in a Washington state hospital. The study indicates that industry standard cleaning guidelines, which were exceeded by hospital staff, may not be sufficient for sterilizing endoscopes adequately.

31 Mar 2015

Allen Institute for Brain Science leads international effort to advance analysis of single neurons

The Allen Institute for Brain Science is spearheading a landmark international effort to define and advance the state-of-the-art digital reconstruction and analysis of single neurons. The project launching today, called BigNeuron, aims to create reliable high-throughput and quantitative 3D reconstructions of the thousands of branches that make up individual neurons: a crucial step to ultimately understanding how the brain encodes information.

31 Mar 2015

Compact MRI and multimodality: an interview with Bernard Siow, UCL

CABI is a preclinical imaging laboratory where we have about ten modalities. We started off with MRI and we have a 9.4T high-field system.

From Bruker BioSpin Group 30 Mar 2015

New drug shows potential against rare type of acute leukemia

Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug that shows potential in laboratory studies against a rare type of acute leukemia. And additional studies suggest the same compound could play a role in prostate cancer treatment as well.

30 Mar 2015

Investigational S-equol nutritional supplement may alleviate certain menopause symptoms

The investigational S-equol nutritional supplement may be a viable agent to alleviate certain menopause symptoms, such as hot flashes, according to a new peer-reviewed article in the March Journal of Women's Health.

30 Mar 2015

Thermo Fisher Scientific to resell Prosolia’s PaperSpray® technology as factory option to its mass spectrometers

Labs performing clinical research and forensic toxicology of dried sample spots can now purchase Thermo Scientific mass spectrometry (MS) systems equipped from the factory with PaperSpray technology, designed to virtually eliminate sample preparation for screening and quantitation of drugs in biological fluid samples.

From Thermo Fisher Scientific Inc. 30 Mar 2015

Scientists successfully produce highly effective medication for malaria from plant waste material

Professor Peter H. Seeberger, Professor Andreas Seidel-Morgenstern and their team are successful in producing a low-cost but highly effective medication for malaria from plant waste material. For their findings, they received the $25,000 award “Humanity in Science” during Pittcon 2015 in New Orleans.

From KNAUER Wissenschaftliche Geräte GmbH 30 Mar 2015

Maternal diet during pregnancy and lactation may influence weight gain in offspring

Maternal diet during pregnancy and lactation may prime offspring for weight gain and obesity later in life, according to Penn State College of Medicine researchers, who looked at rats whose mothers consumed a high-fat diet and found that the offspring's feeding controls and feelings of fullness did not function normally.

30 Mar 2015

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

The American Association for Cancer Research will honor Christopher R. Vakoc, MD, PhD, assistant professor at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, with the 35th annual AACR Outstanding Achievement in Cancer Research Award at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

30 Mar 2015

MDC scientists find solution to increase efficiency of precise genetic modifications

CRISPR-Cas9 is a powerful new tool for editing the genome. For researchers around the world, the CRISPR-Cas9 technique is an exciting innovation because it is faster and cheaper than previous methods. Now, using a molecular trick, Dr. Van Trung Chu and Professor Klaus Rajewsky of the Max Delbrück Center for Molecular Medicine Berlin-Buch and Dr. Ralf Kühn, MDC and Berlin Institute of Health, have found a solution to considerably increase the efficiency of precise genetic modifications by up to eightfold.

30 Mar 2015

Rare genetic mutation explains why flu can kill in rare cases

Nobody likes getting the flu, but for some people, fluids and rest aren't enough. A small number of children who catch the influenza virus fall so ill they end up in the hospital — perhaps needing ventilators to breathe — even while their family and friends recover easily. New research by Rockefeller University scientists, published March 26 in Science, helps explain why: a rare genetic mutation.

30 Mar 2015

MRI technique may help detect cancerous cells

Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn't cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.

30 Mar 2015

Researchers harness gene editing technique in mosquito that infects people with deadly diseases

Traditionally, to understand how a gene functions, a scientist would breed an organism that lacks that gene - "knocking it out" - then ask how the organism has changed. Are its senses affected? Its behavior?

30 Mar 2015

New study may help decode attention deficit disorders

Sometimes being too focused on a task is not a good thing. During tasks that require our attention, we might become so engrossed in what we are doing that we fail to notice there is a better way to get the job done.

30 Mar 2015

Stopping cellular quality-control mechanism can make chemotherapy more effective

A University of Rochester team found a way to make chemotherapy more effective, by stopping a cellular quality-control mechanism, according to a study published today in Nature Communications.

27 Mar 2015

GFT505 demonstrates dose-dependent efficacy on primary endpoint in phase 2 NASH trial

GENFIT, today announces topline results of the phase 2 GOLDEN-505 trial in NASH. Due to the unexpected rate of resolution of NASH in patients randomized to placebo who had early NASH (NAS of 3, placebo response rate>57%), along with the high number of sites for a limited sample size, the study as initially designed did not enable the trial to meet directly the primary endpoint.

27 Mar 2015

Iceland paint a genomic picture for an entire nation

Researchers in Iceland have published the largest ever studies of whole-genome data and effectively deduced the genetic code of “an entire nation.”

26 Mar 2015

Laboratory News and Research

Aspen Dental to open five new locations in Arkansas in 2015

Roche launches new protein melting application for real-time PCR LightCycler 1536 instrument

Researchers report correlative links between family income, brain structure in children

Drug-resistant E. coli outbreak linked to contaminated endoscopes in Washington state hospital

Allen Institute for Brain Science leads international effort to advance analysis of single neurons

Compact MRI and multimodality: an interview with Bernard Siow, UCL

New drug shows potential against rare type of acute leukemia

Investigational S-equol nutritional supplement may alleviate certain menopause symptoms

Thermo Fisher Scientific to resell Prosolia’s PaperSpray® technology as factory option to its mass spectrometers

Scientists successfully produce highly effective medication for malaria from plant waste material

Maternal diet during pregnancy and lactation may influence weight gain in offspring

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

MDC scientists find solution to increase efficiency of precise genetic modifications

Rare genetic mutation explains why flu can kill in rare cases

MRI technique may help detect cancerous cells

Researchers harness gene editing technique in mosquito that infects people with deadly diseases

New study may help decode attention deficit disorders

Stopping cellular quality-control mechanism can make chemotherapy more effective

GFT505 demonstrates dose-dependent efficacy on primary endpoint in phase 2 NASH trial

Iceland paint a genomic picture for an entire nation

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