Antibodies News and Research

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IgG4 serum levels do not show elevation in post-COVID syndrome

In a recent study posted to bioRxiv* preprint server, researchers in Germany assessed the differences in antigen-specific immunoglobulin G (IgG) subtypes between post-COVID syndrome (PCS) patients and convalescent controls.

6 Mar 2023

Zoo study: SARS-CoV-2 surveillance across all mammal species

Researchers from Belgium conduct SARS-CoV-2 surveillance among all mammal species found in two zoos.

6 Mar 2023

Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

A new study published in the International Journal of Infectious Diseases surveyed communities in rural Myanmar to study their exposure to sarbecoviruses and interaction with wildlife.

6 Mar 2023

Study identifies genetic variants influencing human fertility

Fertility is influenced by mechanisms that influence both reproductive biology and human behavior, according to the largest study to date identifying genetic determinants of the number of children an individual may have.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.

6 Mar 2023

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers performed a meta-analysis analyzing randomized controlled trials (RCTs) that evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines, and the dose-response association of humoral responses with vaccine effectiveness.

6 Mar 2023

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model for guiding immunization and prophylactic treatment of one-year-old infants against RSV infections.

3 Mar 2023

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

Certain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, according to a new study from University of Pittsburgh and UPMC researchers that may help explain why ovarian cancer patients respond poorly to chemotherapy or relapse after treatment.

3 Mar 2023

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked messenger ribonucleic acid (mRNA) to the skin.

3 Mar 2023

Researchers develop a potential treatment for autoimmune encephalitis

In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body's own defenses are directed against the central nervous system.

3 Mar 2023

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

3 Mar 2023

Age-associated B cells found to be important drivers of lupus

A group of University of Pittsburgh researchers has given new meaning to "knowing your ABCs."

3 Mar 2023

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Researchers characterized serological neutralizing antibody responses to norovirus among young children, transitioning between sequential GII.4 pandemic strains, DH 2006, NO 2009, and SY 2012.

3 Mar 2023

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

The overall responsiveness of patients with chronic liver disease (CLD) to COVID-19 vaccines has been shown to be decreased in patients with cirrhosis.

2 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Antiverse Ltd (Antiverse), a biotechnology company developing a computational antibody drug discovery platform, today announced the successful identification of functional antibody clusters targeting two G-protein-coupled receptors (GPCRs), both displaying versatile binding profiles and nanomolar affinity.

From Antiverse 1 Mar 2023

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

In a recent study published in the journal Vaccines, researchers in Saudi Arabia and the United States examined immune responses and immunoglobulin G (IgG) cross-reactivity in individuals infected with Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Feb 2023

New funding to accelerate development of potential anti-cancer compound into the clinic

For the past few decades, Dr. Iwao Ojima has been working in his Stony Brook University Department of Chemistry Laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) to develop next-generation anti-cancer agents.

28 Feb 2023

Antibodies News and Research

IgG4 serum levels do not show elevation in post-COVID syndrome

Zoo study: SARS-CoV-2 surveillance across all mammal species

Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

Study identifies genetic variants influencing human fertility

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers develop a potential treatment for autoimmune encephalitis

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

Age-associated B cells found to be important drivers of lupus

Large-scale longitudinal study of neutralizing antibody responses to norovirus in children

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

What is the role of B cells in breast cancer pathology?

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

New funding to accelerate development of potential anti-cancer compound into the clinic

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