Clinical Trial News and Research

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GluFormer outperforms existing AI models in predicting blood sugar levels

Study introduces GluFormer, a transformer-based generative model, to predict glycemic patterns using continuous glucose monitoring data, with significant implications for diabetes management and treatment strategies.

26 Aug 2024

Telehealth mindfulness interventions significantly improve chronic pain outcomes for veterans

Scalable telehealth mindfulness-based interventions (MBIs) effectively improve pain-related function and biopsychosocial outcomes in veterans with chronic pain compared to standard care. The study confirms that low-cost, non-pharmacological treatments like MBIs can be accessible and beneficial via telehealth platforms.

25 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

Olaparib effective against BRCA2-mutated prostate cancer

The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial of 51 patients conducted at the Johns Hopkins Kimmel Cancer Center and three other sites.

23 Aug 2024

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

The anti-obesity medication semaglutide may help to prevent heart attacks and other major adverse cardiac events among overweight people who have cardiovascular disease, whether or not they also have heart failure, according to a new study led by UCL's Professor John Deanfield.

22 Aug 2024

New research challenges belief that weight loss drugs only reduce appetite

A study carried out in St Vincent's University Hospital (SVUH) Dublin challenges the belief that weight loss medications such as Ozempic, Wegovy or Monjaro work just by promoting satiety and making you eat less.

22 Aug 2024

Camu-camu extract reduces liver fat in non-alcoholic fatty liver disease

A research team from Université Laval has shown the benefits of camu-camu on non-alcoholic fatty liver disease, which affects over seven million people in Canada.

21 Aug 2024

Robotic postural stand training with epidural stimulation benefits trunk control during standing

Kessler Foundation researchers have published a new clinical study investigating the effects of robotic postural stand training combined with spinal cord epidural stimulation (Stand-scES) on trunk control in individuals with high-level spinal cord injury (SCI).

21 Aug 2024

Study confirms safety of high and low oxygen levels for cardiac surgery patients

Two out of 10 people who receive cardiac surgery are affected by acute kidney injury, prolonging their hospital stay and increasing their risk for chronic kidney disease, cognitive decline and heart failure.

21 Aug 2024

Study highlights benefits of 20-minute mindful breathing for cancer patients

Twenty minutes of mindful breathing, which focuses a person's attention on their breath, can rapidly reduce the intensity and unpleasantness of cancer pain and relieve the associated anxiety, suggest the findings of a small comparative study, published online in the journal BMJ Supportive & Palliative Care.

20 Aug 2024

Heart-in-a-box technology enhances success of heart transplants

The risk of early heart failure after heart transplantation is lower if the donor heart is stored in a so-called heart-in-a-box instead of in the usual cooler with ice.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Understanding the benefits and risks of dialysis in older patients with kidney failure

Whether dialysis is the best option for kidney failure and, if so, when to start, may deserve more careful consideration, according to a new study.

19 Aug 2024

Scalable mindfulness programs delivered via telehealth show promise for veterans with chronic pain

Mindfulness-based interventions delivered via telehealth in a scalable format can improve pain and overall well-being among veterans with chronic pain, according to new research published today in JAMA Internal Medicine.

19 Aug 2024

UCSF studies point the way toward continuous care for people with Parkinson's disease

Two new studies from UC San Francisco are pointing the way toward round-the-clock personalized care for people with Parkinson's disease through an implanted device that can treat movement problems during the day and insomnia at night.

19 Aug 2024

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

More than half of women globally experience bacterial vaginosis (BV) - an imbalance of naturally occurring microbes in the female genital tract - at least once in their life.

19 Aug 2024

Saliva test offers hope for head and neck cancer patients

But what if a mouthwash-based test to detect biomarkers can help physicians predict disease recurrence in head and neck cancer patients?

16 Aug 2024

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery - including those who would not have been eligible for surgery by conventional criteria - had similar outcomes to patients who received surgery upfront, according to results from a retrospective study.

15 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

Breakthrough malaria vaccine offers long-term protection for pregnant women

In a report published in The Lancet Infectious Diseases (Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomized, double-blind, placebo-controlled, phase 1 and 2 trials) a team led by investigators at the Malaria Research and Training Center (MRTC), Bamako, Mali; the Laboratory of Malaria Immunology and Vaccinology (LMIV), National Institute of Allergy and Infectious Diseases, National Institutes of Health; and Sanaria Inc. describes the durable protective efficacy against malaria shown by Sanaria® PfSPZ Vaccine when administered to women prior to pregnancy.

14 Aug 2024

Clinical Trial News and Research

GluFormer outperforms existing AI models in predicting blood sugar levels

Telehealth mindfulness interventions significantly improve chronic pain outcomes for veterans

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Olaparib effective against BRCA2-mutated prostate cancer

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

New research challenges belief that weight loss drugs only reduce appetite

Camu-camu extract reduces liver fat in non-alcoholic fatty liver disease

Robotic postural stand training with epidural stimulation benefits trunk control during standing

Study confirms safety of high and low oxygen levels for cardiac surgery patients

Study highlights benefits of 20-minute mindful breathing for cancer patients

Heart-in-a-box technology enhances success of heart transplants

Advances in precision medicine enhance cancer immunotherapy

Understanding the benefits and risks of dialysis in older patients with kidney failure

Scalable mindfulness programs delivered via telehealth show promise for veterans with chronic pain

UCSF studies point the way toward continuous care for people with Parkinson's disease

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

Saliva test offers hope for head and neck cancer patients

Neoadjuvant immunotherapy yields comparable outcomes in high-risk liver cancer surgery

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Breakthrough malaria vaccine offers long-term protection for pregnant women

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