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Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

7 Sep 2020

COVID-19 caused substantial disruptions to essential health services in most countries

The COVID-19 pandemic caused substantial disruptions in essential health services in 9 out of 10 countries surveyed by WHO.

7 Sep 2020

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

3 Sep 2020

Two MDC scientists win ERC Starting Grants for pioneering research

Dr. Kathrin de la Rosa and Dr. Ilaria Piazza, who are both junior group leaders at the Max DelbruÌ-ck Center for Molecular Medicine in the Helmholtz Association, have each won European Research Council Starting Grants.

3 Sep 2020

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Reformulated and patented version of well-known generic drug could prove to be a quick, safe and cost-effective way to accelerate recovery and prevent hospitalizations.

3 Sep 2020

HIV and HCV testing at drug detoxification centers can help identify persons at-risk during opioid epidemic

With an increase in HIV and HCV infections as a consequence of the ongoing opioid epidemic, Boston Medical Center researchers found that only a small number of those who test positive for those infections at a drug detoxification center followed up for a clinical visit after their test.

3 Sep 2020

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

Vanderbilt University Medical Center is launching a clinical trial of promising treatments for COVID-19 in the outpatient setting.

2 Sep 2020

Honeybee venom induces cancer cell death in aggressive breast cancer

The new study, published in the journal Nature Precision Oncology, highlights how bees can help combat breast cancer. The research team found that when the venom’s main component, when mixed with existing chemotherapy drugs, reduced tumor growth in laboratory mice.

2 Sep 2020

Novel technique to detect the fungus responsible for causing severe pneumonia

Research staff of the University of Valencia and the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community, among other institutions, have developed a very sensitive and fast in-vitro method for the diagnosis of infection by Pneumocystis jirovecii, a fungus that causes severe pneumonia.

2 Sep 2020

A global vaccine is sufficient to combat COVID-19 infection, indicates study

Genetic analysis of sequences from more than 27,000 individuals infected with the coronavirus that causes COVID-19 reveals that the virus has mutated minimally since December 2019, suggesting one vaccine would be sufficient to combat global infections.

2 Sep 2020

Newly approved drugs in Canada lack key pediatric drug information

Newly approved drugs in Canada lack important pediatric drug information in their product monograph, according to an analysis led by McMaster University and McMaster Children's Hospital.

1 Sep 2020

Spike ferritin nanoparticles show potential as SARS-CoV-2 vaccine

Now, a new study published on the preprint server bioRxiv* in August 2020 reports the induction of neutralizing antibodies in mice by a single dose of a ferritin nanoparticle-based vaccine containing the spike protein.

1 Sep 2020

Researchers launch study to evaluate safety of HIV prevention methods in breastfeeding women

The development of safe and effective HIV prevention methods for cisgender women has long been a global health priority, yet research in women during pregnancy and breastfeeding, when they are most vulnerable to infection, has lagged years behind.

31 Aug 2020

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Early on in the coronavirus disease (COVID-19) pandemic, there was little data on the virus and how it affects the body. As the virus spread across the globe, data showed that some people were at a higher risk of developing severe disease and dying from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

31 Aug 2020

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

A research group from Slovenia, Switzerland, and Germany shows how nanoscaffolded assemblies may neutralize interaction between the SARS-CoV-2 spike protein and cell receptor, providing adequate protection in a surrogate infection assay and warranting the advance of such platforms in the pursuit for the effective vaccine.

31 Aug 2020

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection.

31 Aug 2020

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection.

29 Aug 2020

Universal health coverage study reveals that the world likely to fall short of WHO goal

A new study projects that 3.1 billion people will still lack effective health service coverage in 2023, with 968 million of those residing in South Asia.

28 Aug 2020

HIV 1 News and Research

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

COVID-19 caused substantial disruptions to essential health services in most countries

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

Two MDC scientists win ERC Starting Grants for pioneering research

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

HIV and HCV testing at drug detoxification centers can help identify persons at-risk during opioid epidemic

VUMC launches clinical trial of promising COVID-19 treatments in outpatient setting

Honeybee venom induces cancer cell death in aggressive breast cancer

Novel technique to detect the fungus responsible for causing severe pneumonia

A global vaccine is sufficient to combat COVID-19 infection, indicates study

Newly approved drugs in Canada lack key pediatric drug information

Spike ferritin nanoparticles show potential as SARS-CoV-2 vaccine

Researchers launch study to evaluate safety of HIV prevention methods in breastfeeding women

Majority of U.S. COVID-19 fatalities had underlying medical conditions

A nanoscaffolding approach for rapid design of highly immunogenic SARS-CoV-2 vaccines

New dual CAR T cell immunotherapy shows enhanced therapeutic potency to fight HIV

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Universal health coverage study reveals that the world likely to fall short of WHO goal

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