Protein C News and Research

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Changes in skin and lymphatic system due to age facilitate melanoma metastasis

Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute.

3 Oct 2018

New way of using natural killer cells makes immunotherapy viable to more patients

Immunotherapy is making headlines for saving the lives of hundreds of cancer patients including former President Jimmy Carter. But many of these therapies, only work for a small portion of people who have a specific molecule called PDL1 in their cancer makeup.

3 Oct 2018

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids.

3 Oct 2018

Understanding immune system's balancing act could help in prevention, treatment of IBD

Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease.

3 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

USDA scientist tries to naturally enhance minerals of wheat flours

Is biofortification the best thing since sliced bread? Well, biofortified wheat could certainly make it easier to help some humans get proper nutrition.

3 Oct 2018

Some people can avoid depression by maintaining serotonin level throughout the year

Some people can adjust to environmental stressors to avoid depression. Women need to do this more than men to avoid getting depressed.

3 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Aggressive breast cancer cells hijack protective protein to aid growth

A new study has revealed that a protein known to protect healthy cells also protects cancer cells in aggressive breast cancer.

2 Oct 2018

New tool can help researchers split and reassemble proteins

Researchers have developed a computational tool that makes it possible to split proteins and then restore them to functionality.

2 Oct 2018

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Scientists have discovered that a potassium channel called KCNB1 can trigger the formation of amyloid-beta plaques seen in Alzheimer's disease.

2 Oct 2018

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Researchers at Rutgers Robert Wood Johnson Medical School have identified an important step in the process that allows our bodies to fight viruses.

2 Oct 2018

New, more efficient method for generating brain stem cells in the lab

In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell in the laboratory.

1 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Protein C News and Research

Changes in skin and lymphatic system due to age facilitate melanoma metastasis

New way of using natural killer cells makes immunotherapy viable to more patients

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

Understanding immune system's balancing act could help in prevention, treatment of IBD

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Aggressive breast cancer hijacks normal protective physiological process to survive

USDA scientist tries to naturally enhance minerals of wheat flours

Some people can avoid depression by maintaining serotonin level throughout the year

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Aggressive breast cancer cells hijack protective protein to aid growth

New tool can help researchers split and reassemble proteins

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Immune protein 'flutters' like a butterfly in search of viruses, finds study

New, more efficient method for generating brain stem cells in the lab

Genetic variants reveal novel therapeutic targets for chronic kidney disease

Why patients with ALL relapse after CAR-T cell therapy

Why patients with ALL relapse after CAR-T cell therapy

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Researchers deplete key protein for DNA replication using protein degradation system

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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