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New collaborative study aims to identify mutations to improve clinical management of breast cancer

Mr. Peter Goodhand, President of The Ontario Institute for Cancer Research (OICR), today announced a new collaborative research study in partnership with Thermo Fisher Scientific and Queen's University to help bring more targeted diagnosis and treatment to breast cancer patients in the future.

18 Aug 2016

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer.

18 Aug 2016

Salk researchers identify new mechanism for Alzheimer's risk gene

For decades, scientists have known that people with two copies of a gene called apolipoprotein E4 (ApoE4) are much more likely to have Alzheimer's disease at age 65 than the rest of the population.

18 Aug 2016

New ATA recommendations offer guidance for managing all forms of thyrotoxicosis

New evidence-based recommendations from the American Thyroid Association provide guidance to clinicians in the management of patients with all forms of thyrotoxicosis (excessively high thyroid hormone activity), including hyperthyroidism.

18 Aug 2016

Schizophrenia vulnerability emerged after divergence of modern humans from Neanderthals

Schizophrenia poses an evolutionary enigma. The disorder has existed throughout recorded human history and persists despite its severe effects on thought and behavior, and its reduced rates of producing offspring.

17 Aug 2016

Molecular alarm clock awakens ovules from resting period

At the start of reproductive life an ovary contains, on average, several thousands of immature ovules in a resting state that can last for several decades.

17 Aug 2016

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Scientists at The Scripps Research Institute (TSRI) have taken a big step toward the laboratory re-creation of the “RNA world,” which is generally believed to have preceded modern life forms based on DNA and proteins.

17 Aug 2016

Researchers discover new set of bacterial cell wall synthesizers

Harvard Medical School scientists have identified a new family of proteins that virtually all bacteria use to build and maintain their cell walls.

17 Aug 2016

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Maintaining appropriate levels of proteins within cells largely relies on a cellular component called the proteasome, which degrades unneeded or defective proteins to recycle the components for the eventual assembly of new proteins.

16 Aug 2016

Latinos age more slowly than other ethnic groups, reveals UCLA study

A UCLA study is the first to show that Latinos age at a slower rate than other ethnic groups. The findings, published in the current issue of Genome Biology, may one day help scientists understand how to slow the aging process for everyone.

16 Aug 2016

Mathematicians developing new statistical methods to predict bacterial epidemics

Mathematicians are now developing completely new statistical calculations on the world's fastest computers in order to be able to predict how epidemics of dangerous hospital bacteria spread.

16 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

In middle aged populations, the risks of cardiovascular conditions are progressively lower the longer a person's parents lived past 69 years old, according to a study of 186,000 participants using a voluntary database published today in the Journal of the American College of Cardiology.

16 Aug 2016

Study offers clues about how genetic mutations can increase risk of psychiatric disorders

Brain scans have revealed how a genetic mutation linked to major psychiatric disorders affects the structure, function and chemistry of the brain.

16 Aug 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output.

12 Aug 2016

St. Jude scientists identify key innate immune sensor that attacks influenza virus

St. Jude Children's Research Hospital immunologists have identified the protein trigger in the body's quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death.

12 Aug 2016

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists at The Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. The findings could lead to new ways to target the disease.

12 Aug 2016

Nigerian Government reports 2 children paralyzed by wild poliovirus

After more than two years without wild poliovirus in Nigeria, the Government reported today that 2 children have been paralyzed by the disease in the northern Borno state.

12 Aug 2016

BCL-2 inhibitor shows promise in AML patients

Patients whose acute myelogenous leukemia (AML) had relapsed or was resistant to chemotherapy and those who were deemed unable to tolerate chemotherapy experienced responses to the selective BCL-2 inhibitor venetoclax (Venclexta), with complete remissions in some, according to phase II clinical trial data.

12 Aug 2016

Genetic News and Research

New collaborative study aims to identify mutations to improve clinical management of breast cancer

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

Salk researchers identify new mechanism for Alzheimer's risk gene

New ATA recommendations offer guidance for managing all forms of thyrotoxicosis

Schizophrenia vulnerability emerged after divergence of modern humans from Neanderthals

Molecular alarm clock awakens ovules from resting period

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Researchers discover new set of bacterial cell wall synthesizers

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Latinos age more slowly than other ethnic groups, reveals UCLA study

Mathematicians developing new statistical methods to predict bacterial epidemics

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

Study offers clues about how genetic mutations can increase risk of psychiatric disorders

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

TUM scientists isolate and archive cultured bacterial strains from mouse microbiome

St. Jude scientists identify key innate immune sensor that attacks influenza virus

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Nigerian Government reports 2 children paralyzed by wild poliovirus

BCL-2 inhibitor shows promise in AML patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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