Protein C News and Research

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Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel.

21 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Study reveals promising new drug candidate to treat acute renal failure

A protein produced by the human body appears to be a promising new drug candidate to treat conditions that lead to acute renal failure. This is shown by a study conducted at São Paulo State University in São José do Rio Preto, Brazil.

20 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

A clinical trial testing infusions of combination antibodies in people living with HIV has begun at the National Institutes of Health.

20 Sep 2018

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so.

20 Sep 2018

New type of fatty acid can slow down overreactive immune system

Sometimes, the body's otherwise intelligent immune system mistakenly attacks the body's healthy tissue by responding to infections that do not exist.

20 Sep 2018

Innovative approach for developing vaccine against most prevalent human malaria parasite

A novel study indicates promising avenues in an innovative approach for developing a vaccine against Plasmodium vivax, the most prevalent human malaria parasite outside sub-Saharan Africa.

20 Sep 2018

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

Sesen Bio, Inc., a late-stage clinical company developing fusion protein therapies for the treatment of cancer, today announced that the company will present its three-month Phase 3 VISTA Trial data during a poster session at the Global Congress on Bladder Cancer 2018.

20 Sep 2018

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Applied DNA Sciences Inc. announced today that LineaRx, Inc., its wholly-owned subsidiary focused on next-generation biotherapeutics, has signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L., biotechnology companies focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal markets, respectively.

20 Sep 2018

Rice seeds could hold key to preventing HIV infections

As incredible as it sounds, a rice paddy field could one day yield an inexpensive way to prevent HIV.

20 Sep 2018

Study finds factors within cell influencing variability in amount of protein produced

You can think of a cell in your body like a miniature factory, creating a final product called proteins, which carry out various tasks and functions.

20 Sep 2018

Alzheimer’s diagnosis might become simpler with new brain imaging method

Accurate diagnosis of Alzheimer’s disease may be difficult in most patients as similar symptoms can be seen in several other disease conditions as well.

20 Sep 2018

UNC scientists reveal new approach to prevent obesity and diabetes

Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet.

19 Sep 2018

New chemo-optogenetic method enables multi-directional activity control of cellular processes

Cells need for reactions on environmental changes and a balanced system of signaling cascades within the cell. Proteins outside of the cell, on the cellular surface, inside the cellular membrane, and within the cell orchestrate many fine-tuned signaling pathways, which result in adequate reactions on the environmental conditions or changes in the organism itself.

19 Sep 2018

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

An analysis of the NRG Oncology clinical trial NRG-GY003 suggests that adding ipilimumab, a monoclonal antibody that targets the protein receptor CTLA-4, to a regimen with the checkpoint inhibitor nivolumab could improve the proportion with tumor response and progression-free survival hazard rates for women with recurrent epithelial ovarian cancer.

19 Sep 2018

Study shows how cellular waste disposal processes also promote inflammation

A study conducted at the University of California has revealed how cells use G-protein-coupled receptors (GPCRs) and their waste disposal systems to mediate inflammation.

19 Sep 2018

Manipulating nuclear pore number could lead to new way of treating cancer

Researchers at the Salk institute have found a way to manipulate the number of nuclear pores present in the perimeter of the nucleus.

19 Sep 2018

Study finds why some human genes are more popular with biomedical researchers

Historical bias is a key reason why biomedical researchers continue to study the same 10 percent of all human genes while ignoring many genes known to play roles in disease, according to a study publishing September 18 in the open access journal PLOS Biology, led by Thomas Stoeger and Luís Amaral of Northwestern University, and colleagues. This bias is bolstered by research funding mechanisms and social forces.

19 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Protein C News and Research

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Study reveals promising new drug candidate to treat acute renal failure

Novel mathematical approach uncovers existence of unsuspected biological cycles

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

CWRU receives NIH grant to learn how non-coding genes contribute to spread of colorectal cancer

New type of fatty acid can slow down overreactive immune system

Innovative approach for developing vaccine against most prevalent human malaria parasite

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Rice seeds could hold key to preventing HIV infections

Study finds factors within cell influencing variability in amount of protein produced

Alzheimer’s diagnosis might become simpler with new brain imaging method

UNC scientists reveal new approach to prevent obesity and diabetes

New chemo-optogenetic method enables multi-directional activity control of cellular processes

Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer

Study shows how cellular waste disposal processes also promote inflammation

Manipulating nuclear pore number could lead to new way of treating cancer

Study finds why some human genes are more popular with biomedical researchers

Researchers describe cell mechanism that optimizes proteins production in stressful situations

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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