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Self-collection of blood for COVID-19 antibody testing may be a reliable and easy alternative

Some evidence suggests that IgGs appear at 6-15 days after infection and may persist for months. However, large-scale testing over time is required to understand the immunological response to COVID-19 with greater accuracy. A recent pilot study published on the preprint server medRxiv in September 2020 reports the use of self-collected capillary blood for serology, with highly promising results.

29 Sep 2020

Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine.

29 Sep 2020

UC researchers find potential treatment that could be applied to COVID-19

By examining preexisting research for other conditions, researchers at the University of Cincinnati have found a potential treatment that could be applied to COVID-19.

29 Sep 2020

Novel immunotherapy platform can connect mussel adhesive proteins to the antibodies

Antibody-based immunotherapy is one of treatment options for cancer immunotherapy by modulating our immune system with therapeutic antibodies.

29 Sep 2020

Developing a model to predict how artillery blast exposures affect the brains of military personnel

University of Virginia School of Medicine researchers are partnering with the U.S. Navy and National Institutes of Health to develop a model predicting how regular exposure to artillery blasts affects the brains of military personnel.

29 Sep 2020

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body.

29 Sep 2020

Corralling the facts on herd immunity

For a term that's at least 100 years old, "herd immunity" has gained new life in 2020.

29 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

Study identifies thousands of deaths caused by heart disease and stroke during COVID-19 pandemic

A major new study has identified 2085 excess deaths in England and Wales due to heart disease and stroke during the peak of the COVID-19 pandemic. On average, that is 17 deaths each day over four months that probably could have been prevented.

29 Sep 2020

Specific anti-bacterial T cells are strongly activated in people with moderate to severe COVID-19

A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. The findings contribute to increased understanding about how our immune system responds against COVID-19 infection.

29 Sep 2020

ACD study underscores the prevalence of malnutrition among obese individuals

A new editorial accompanying a study published in the Journal of the American College of Cardiology is bringing attention to the underappreciated and often overlooked issue of malnutrition among those who are obese.

29 Sep 2020

Fasting blood glucose levels upon admission tied to COVID-19 prognosis, study finds

In the study, which appeared on the pre-print open-source medRxiv* server, the investigators aimed to determine the prognostic value of blood glucose in predicting outcomes in COVID-19 disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

SARS-CoV-2 re-infection is real but rare: Case study

Now, American researchers have looked at all reported cases of re-infection and the possible reasons behind them. Their study titled, “Re-infection with SARS-CoV-2 and Failure of Humoral Immunity: a case report,” is published online on the preprint server medRxiv in September 2020.

28 Sep 2020

Cincinnati Children's research leads to approval of new drug for hypereosinophilic syndrome

Following two decades of research on a group of rare diseases called hypereosinophilic syndrome at Cincinnati Children's Hospital Medical Center, the U.S. Food and Drug Administration has approved the drug Nucala (mepolizumab) for use in the treatment of patients with hypereosinophilic syndrome.

28 Sep 2020

Healthy vitamin D levels could reduce COVID-19 complications

Published in the journal PLOS ONE, the study investigates the link between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes and parameters of immune function and mortality due to COVID-19.

28 Sep 2020

Study pinpoints heating element in vaping devices as cause for lung injuries

Early results of an experimental vaping study have shown significant lung injury from E-cigarette (eC) devices with nickel-chromium alloy heating elements.

28 Sep 2020

Hamsters and ferrets clear low dose SARS-CoV-2 infection in 14 days

A recent study by French researchers has demonstrated that experimental exposure to severe acute respiratory coronavirus 2 (SARS-CoV-2) is capable of inducing mild infection in hamsters and ferrets within 7 – 10 days of exposure. However, the infection completely resolves within 14 days. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Life-threatening COVID-19 associated with specific genetic variants

Results of a genome-wide association study on 2,244 critically-ill patients due to coronavirus disease (COVID-19) from 208 intensive care units across the United Kingdom revealed significant host-specific genetic determinants that can predispose people to the severe form of the disease. The report is currently available on the medRxiv preprint server.

28 Sep 2020

Blood News and Research

Self-collection of blood for COVID-19 antibody testing may be a reliable and easy alternative

Dartmouth TB vaccine moves one step closer to a full Phase 3 efficacy trial

UC researchers find potential treatment that could be applied to COVID-19

Novel immunotherapy platform can connect mussel adhesive proteins to the antibodies

Developing a model to predict how artillery blast exposures affect the brains of military personnel

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Corralling the facts on herd immunity

Induction of acute senescence may be a necessary process in hemorrhagic shock

Phase 1 trial of new class of drugs shows promise in range of advanced cancers

Study identifies thousands of deaths caused by heart disease and stroke during COVID-19 pandemic

Specific anti-bacterial T cells are strongly activated in people with moderate to severe COVID-19

ACD study underscores the prevalence of malnutrition among obese individuals

Fasting blood glucose levels upon admission tied to COVID-19 prognosis, study finds

SARS-CoV-2 re-infection is real but rare: Case study

Cincinnati Children's research leads to approval of new drug for hypereosinophilic syndrome

Healthy vitamin D levels could reduce COVID-19 complications

Study pinpoints heating element in vaping devices as cause for lung injuries

Hamsters and ferrets clear low dose SARS-CoV-2 infection in 14 days

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

Life-threatening COVID-19 associated with specific genetic variants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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