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Salk research in yeast leads to serendipitous finding about hypomyelinating leukodystrophy

Studying the fundamental aspects of biology can sometimes lead to unexpected findings that directly relate to human disease. In one of the latest examples of scientific serendipity, researchers from the Salk Institute found that an important quality control mechanism in baker's yeast is closely connected to hypomyelinating leukodystrophy, a debilitating disease found in children.

17 Sep 2018

Investigators pinpoint exact stage of retinoblastoma development in children

Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses.

14 Sep 2018

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer.

14 Sep 2018

Calorie dense, nutrient deficient meals common across the world

A new study has shown that although we have a good supply of calorie-rich foods, most people are lacking several micronutrients in their diet.

14 Sep 2018

P3 microplate accelerates removal of interfering proteins in biological samples

Porvair Sciences reports how its P3 microplate can be used to accelerate removal of interfering proteins from serum, plasma or even whole blood samples prior to analysis by Liquid Chromatography / Mass Spectrometry.

From Porvair Sciences Limited 14 Sep 2018

Thermo Fisher Scientific and Diamond collaborate to launch new cryo-EM capability for use in life sciences industry

An agreement to launch a new cryo-EM capability for use in the life sciences industry sector by Thermo Fisher Scientific, one of the world leaders in high-end scientific instrumentation, and Diamond Light Source, the UK’s national synchrotron and one of the most advanced scientific facilities in the world, was announced today at the official opening of the new national electron bio-imaging center at Diamond.

From Thermo Fisher Scientific – Electron Microscopy Solutions 14 Sep 2018

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis, a chronic and aggressive liver condition.

14 Sep 2018

Study reveals how dangerous bacterium shares its genetic information

Bacteria are very sneaky in their efforts to develop resistance to antibiotics. Some strains of bacteria package up the genetic instructions for how they defend themselves and cause disease, and pass this information on to neighbouring, naïve, bacteria - essentially gifting their colleagues with the defences they need to survive against our medical armoury of antibiotics.

14 Sep 2018

Study: Children with acute lymphoblastic leukemia are immunologically disparate at birth

Neonatal concentrations of eight detectable inflammatory markers were significantly different in children later diagnosed with B-cell precursor acute lymphoblastic leukemia (ALL) compared with controls.

14 Sep 2018

Study could pave way for new therapies to reverse aging in human cells

Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age.

14 Sep 2018

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss.

14 Sep 2018

Researchers describe mechanism that sets stage for fate decision of T cells

After a pathogen infects the body, the immune system responds with a remarkable -- and remarkably complicated -- cascade of events.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

Dietary fiber may delay memory loss, brain inflammation during old age

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function.

14 Sep 2018

Rare antibodies could be key ingredients in therapeutics capable of neutralizing many Ebola types

Two new studies by scientists at Scripps Research are bringing Ebola virus's weaknesses into the spotlight, showing for the first time exactly how human and mouse antibodies can bind to the virus and stop infection--not only for Ebola virus, but for other closely related pathogens as well.

13 Sep 2018

Protein C News and Research

Salk research in yeast leads to serendipitous finding about hypomyelinating leukodystrophy

Investigators pinpoint exact stage of retinoblastoma development in children

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Calorie dense, nutrient deficient meals common across the world

P3 microplate accelerates removal of interfering proteins in biological samples

Thermo Fisher Scientific and Diamond collaborate to launch new cryo-EM capability for use in life sciences industry

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Study reveals how dangerous bacterium shares its genetic information

Study: Children with acute lymphoblastic leukemia are immunologically disparate at birth

Study could pave way for new therapies to reverse aging in human cells

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Researchers describe mechanism that sets stage for fate decision of T cells

Discovery of key mechanism may lead to more functional skin grafts for burn victims

Dietary fiber may delay memory loss, brain inflammation during old age

Rare antibodies could be key ingredients in therapeutics capable of neutralizing many Ebola types

Study provides complete picture of HPV virus-head and neck cancer connections

Drug combination targets pre-leukemia stem cells

Highly personalized approach may help immune cells to eliminate melanoma

Mitochondrial pathway found to be involved in breast cancer

Scientists identify how viral protein promotes fatal disease caused by Nipah and Hendra viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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