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Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Researchers at MIT and Brigham and Women's Hospital have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells. Using these cells, scientists could develop and test new drugs to treat diseases such as ulcerative colitis.

3 Dec 2013

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination.

27 Nov 2013

Garlic compounds can kill foodborne pathogen present in infant formula powder

Garlic may be bad for your breath, but it's good for your baby, according to a new study from the University of British Columbia.

26 Nov 2013

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson's disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body.

24 Nov 2013

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Researchers create new statistical tools to find clues about cancer from raw data

Researchers at Rice University, Baylor College of Medicine (BCM) and the University of Texas at Austin are working together to create new statistical tools that can find clues about cancer that are hidden like needles in enormous haystacks of raw data.

15 Nov 2013

Analysis of carbendazim in orange juice and wine

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS). Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health.

From Bruker 13 Nov 2013

immatics, Roche enter into cancer vaccine and immunotherapy deal

immatics biotechnologies GmbH and Roche today announced a strategic research and development collaboration covering multiple cancer vaccines and immunotherapeutics.

13 Nov 2013

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

A bicoastal group of scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) was recently awarded a three-year grant from the U.S. Department of the Air Force to assess the potential toxicity of large collections of chemicals.

13 Nov 2013

Hologic's Aptima HPV 16 18/45 genotype assay gets FDA approval for use on Panther system

Hologic, Inc., a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems and surgical products, with an emphasis on serving the healthcare needs of women, announced today that the U.S. Food and Drug Administration has approved the Aptima HPV 16 18/45 genotype assay for use on the Company's fully automated Panther system.

From Hologic, Inc. 8 Nov 2013

Bruker to hold NMR webinar in late November

One of the world's leading analytical instrumentation companies is presenting an educational webinar on nuclear magnetic resonance (NMR) later this month.

From Bruker BioSpin Division 5 Nov 2013

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA).

From Cellectricon 31 Oct 2013

Unique approach to help discover how cell changes shape in response to topographies

Cells in the human body change shape as they crawl, split, or cling to other surfaces, but while the scientific literature is filled with examples of how cell shapes shift in response to things they touch, little is known about the rules that govern these changes. And there has been no high-throughput way to systematically test different topologies against different types of cells to optimize the surface of something like a medical implant.

24 Oct 2013

U of T researchers develop method to screen human stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods.

23 Oct 2013

High throughput ChIP microplate launched by Porvair

Porvair Sciences has announced that it will officially launch Chromatrap®96 HT – an innovative 96-well chromatin immunoprecipitation (ChIP) assay plate at Epigenomics of Common Diseases (Wellcome Trust, Cambridge, UK) from 7th-10th November 2013.

From Chromatrap® - Porvair Sciences Ltd 17 Oct 2013

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Tepnel Pharma Services, a division of Hologic, Inc., is now using Hologic’s proprietary Invader and Invader Plus technology as part of its Molecular Genetic Services offering, enabling it to offer customers a more cost effective and high throughput genotyping and copy number variation service.

From Hologic, Inc. 15 Oct 2013

New optical imaging technique can accurately differentiate breast cancer subtypes

An optical imaging technique that measures metabolic activity in cancer cells can accurately differentiate breast cancer subtypes, and it can detect responses to treatment as early as two days after therapy administration, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

15 Oct 2013

Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.