High Throughput News and Research

RSS

Researchers develop novel system to image worm brain activity

A research team at Worcester Polytechnic Institute and The Rockefeller University in New York has developed a novel system to image brain activity in multiple awake and unconstrained worms. The technology, which makes it possible to study the genetics and neural circuitry associated with animal behavior, can also be used as a high-throughput screening tool for drug development targeting autism, anxiety, depression, schizophrenia, and other brain disorders.

18 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Researchers create new statistical tools to find clues about cancer from raw data

Researchers at Rice University, Baylor College of Medicine (BCM) and the University of Texas at Austin are working together to create new statistical tools that can find clues about cancer that are hidden like needles in enormous haystacks of raw data.

15 Nov 2013

Analysis of carbendazim in orange juice and wine

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS). Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health.

From Bruker 13 Nov 2013

immatics, Roche enter into cancer vaccine and immunotherapy deal

immatics biotechnologies GmbH and Roche today announced a strategic research and development collaboration covering multiple cancer vaccines and immunotherapeutics.

13 Nov 2013

Sanford-Burnham scientists receive grant to assess potential toxicity of large collections of chemicals

A bicoastal group of scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) was recently awarded a three-year grant from the U.S. Department of the Air Force to assess the potential toxicity of large collections of chemicals.

13 Nov 2013

Hologic's Aptima HPV 16 18/45 genotype assay gets FDA approval for use on Panther system

Hologic, Inc., a leading developer, manufacturer and supplier of premium diagnostic products, medical imaging systems and surgical products, with an emphasis on serving the healthcare needs of women, announced today that the U.S. Food and Drug Administration has approved the Aptima HPV 16 18/45 genotype assay for use on the Company's fully automated Panther system.

From Hologic, Inc. 8 Nov 2013

Bruker to hold NMR webinar in late November

One of the world's leading analytical instrumentation companies is presenting an educational webinar on nuclear magnetic resonance (NMR) later this month.

From Bruker BioSpin Group 5 Nov 2013

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA).

From Cellectricon 31 Oct 2013

Unique approach to help discover how cell changes shape in response to topographies

Cells in the human body change shape as they crawl, split, or cling to other surfaces, but while the scientific literature is filled with examples of how cell shapes shift in response to things they touch, little is known about the rules that govern these changes. And there has been no high-throughput way to systematically test different topologies against different types of cells to optimize the surface of something like a medical implant.

24 Oct 2013

U of T researchers develop method to screen human stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods.

23 Oct 2013

High throughput ChIP microplate launched by Porvair

Porvair Sciences has announced that it will officially launch Chromatrap®96 HT – an innovative 96-well chromatin immunoprecipitation (ChIP) assay plate at Epigenomics of Common Diseases (Wellcome Trust, Cambridge, UK) from 7th-10th November 2013.

From Chromatrap® - Porvair Sciences Ltd 17 Oct 2013

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Tepnel Pharma Services, a division of Hologic, Inc., is now using Hologic’s proprietary Invader and Invader Plus technology as part of its Molecular Genetic Services offering, enabling it to offer customers a more cost effective and high throughput genotyping and copy number variation service.

From Hologic, Inc. 15 Oct 2013

New optical imaging technique can accurately differentiate breast cancer subtypes

An optical imaging technique that measures metabolic activity in cancer cells can accurately differentiate breast cancer subtypes, and it can detect responses to treatment as early as two days after therapy administration, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

15 Oct 2013

Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.

15 Oct 2013

Study: Distinct behavior of proteins reflects common biochemical principles

Researchers from Case Western Reserve University School of Medicine have found unexpected similarities between proteins that were thought to be fundamentally different.

9 Oct 2013

Newly discovered compound could be developed as antifungal drug to treat fungal infections

On a molecular level, you have more in common with shower curtain mold or the mushrooms on your pizza than you might think. Humans and fungi share similar proteins, a biological bond that makes curing fungal infections difficult and expensive.

7 Oct 2013

Scientists discover how to quantitatively observe cellular processes taking place on "lab on chip" devices

A team of scientists from The University of Texas at Arlington and MIT has figured out how to quantitatively observe cellular processes taking place on so-called "lab on a chip" devices in a silicon environment.

3 Oct 2013

libragen contributes to success of PolyModE

libragen, a contract research organization dedicated to biocatalysis and metagenomics, has been a major contributor to the success of PolyModE (Polysaccharide Modifying Enzymes), a large collaborative research project funded by the European Community. The project, which began in 2009 and ended in April this year, looked at developing novel polysaccharide modifying enzymes for the optimized use of hydrocolloids as, for example, food additives or novel therapeutic agents in the food sciences and medical industries. Researchers focused on six industry-targeted hydrocolloids (alginates, carrageenans, chitosans, glycosaminoglycans, pectins, and xanthan gums) where traditional chemistry fails to achieve a certain desired modification.

2 Oct 2013

IMSGC scientists identify 48 genetic variants influencing risk of developing MS

Scientists of the International Multiple Sclerosis Genetics Consortium (IMSGC) have identified an additional 48 genetic variants influencing the risk of developing multiple sclerosis.

1 Oct 2013