Malignant News and Research

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Study shows lymph node stage may have clinical importance among NSCLC patients with M1a disease

Analysis of a large non-small cell lung cancer (NSCLC) patient cohort with stage IV M1a disease identified lymph node staging as having clinical significance and an impact on prognosis.

25 Aug 2016

New MRI method detects low zinc levels to help identify healthy prostate tissue from cancer

A novel MRI method that detects low levels of zinc ion can help distinguish healthy prostate tissue from cancer, UT Southwestern Medical Center radiologists have determined.

23 Aug 2016

Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Human papillomavirus (HPV) is one of the most common sexually transmitted infections in the United States and has been identified as a primary cause of cervical cancer in women.

19 Aug 2016

New research reveals vanity could play crucial role in protecting young women from harmful UV light

New research published in Cogent Psychology, examines the way sun safe messages are conveyed to young women, and reveals their vanity could play a vital role in protecting them from harmful UV light.

18 Aug 2016

Research findings open avenues for creating new classes of anticancer drugs

A new study at Los Alamos National Laboratory and in collaboration with Stanford Synchrotron Radiation Lightsource greatly improves scientists' understanding of the element actinium. The insights could support innovation in creating new classes of anticancer drugs.

18 Aug 2016

Young adult women support stricter regulations, but against total ban of indoor tanning

Most young adult women who regularly visit indoor tanning salons support the introduction of policies to make it safer, but are against a total ban. This is according to a study led by Darren Mays of Georgetown University Medical Center in the US, in the journal Translational Behavioral Medicine: Practice, Policy, Research, published by Springer.

17 Aug 2016

New study uncovers how chromosomal changes impact tumor formation and growth

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

16 Aug 2016

Scientists create stable boron carrier for targeted radiation-based tumour therapies

Targeted radiation-based therapies for treating cancerous tumours such as 'boron neutron capture therapy' (BNCT), rely on the efficient and effective delivery of the capture agent (in this case, boron) to the tumour.

11 Aug 2016

Diabetes mellitis coexisting with solid-organ malignancies linked to hospitalization risks

Future Science Group today announced the publication of a new article in Future Science OA examining the effects of diabetes on hospitalization risk, chances of multiple admissions, and length of hospitalization stay, for patients suffering from solid-organ malignancies such as breast, colorectal, lung and pancreas, among others.

10 Aug 2016

Wistar scientists discover novel mechanism that helps tumors adapt to hypoxia

One of the many reasons tumors are so difficult to treat is that they are able to adapt whenever they are exposed to unfavorable conditions.

9 Aug 2016

Oncolytic virotherapy medicine shows positive treatment outcomes in late-stage cancer patients

The surprisingly positive treatment outcomes using Rigvir virotherapy for late stages cancer patients were recently published.

8 Aug 2016

Studies show insurance status may impact patients' health outcomes following cancer diagnosis

Two new studies indicate that health insurance status may impact patients' health outcomes following a diagnosis of cancer.

8 Aug 2016

Physicists receive three-year NSF grant to apply principles of soft-matter physics to cancer therapy

Three physicists in the College of Arts and Sciences are using a major grant to study the dynamics and interactions of cancer cells.

5 Aug 2016

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Lymphoma is a cancer that affects lymphocytes, a type of white blood cell. The disease originates in a lymphoid organ (lymph node, spleen, or bone marrow) before spreading through the blood to infiltrate not only other lymphoid organs but also other tissues.

4 Aug 2016

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated.

28 Jul 2016

Researchers find oldest evidence of cancer in 1.7 million-year-old fossil

An international team of researchers led by scientists from the University of the Witwatersrand's Evolutionary Studies Institute and the South African Centre for Excellence in PalaeoSciences today announced in two papers, published in the South African Journal of Science, the discovery of the most ancient evidence for cancer and bony tumours yet described in the human fossil record.

28 Jul 2016

New combination treatment improves overall survival in patients with malignant melanoma

Among patients with melanoma, those who received both ipilimumab (Yervoy) and local peripheral treatments such as radiotherapy or electrochemotherapy had significantly prolonged overall survival compared with those who received only ipilimumab, according to a retrospective clinical study.

27 Jul 2016

Genetic profiling offers new avenues for treatment of cancer, study finds

Genetic profiling of cancer tumors provides new avenues for treatment of the disease, according to a study conducted by Sanford Health and recognized by the American Society of Clinical Oncology.

27 Jul 2016

New study uncovers way to characterize black box of malignant melanoma

When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions of metastatic cells with the brain microenvironment remain shrouded in mystery.

26 Jul 2016

Researchers identify specific pathways involved in development of mucormycosis

Research published today in the journal, Nature Communications, provides new insights into the evolution of Mucorales fungi, which cause a fatal infection in ever-increasing segments of patient population, and several molecular pathways that might be exploited as potential therapeutic or diagnostic targets.

22 Jul 2016