Protein C News and Research

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Researchers hope to translate mRNA drugs from lab to medicine cabinet

In cells, ribosomes translate messenger RNA into proteins. And in the nascent field of mRNA therapeutics, researchers and investors are hoping to translate mRNA drugs from the lab to the medicine cabinet.

6 Sep 2018

Researchers make discovery about yeast metabolism that could help drug developers

Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

6 Sep 2018

New method may speed up development of novel drugs

Researchers of the University of Würzburg have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.

6 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Study finds ways to maximize nutrition and growth for tiniest of premature infants

The tiniest of premature infants - weighing just over two pounds at birth on average - start out receiving nutrition intravenously. Over the next several days or weeks, they are transitioned to enteral (or through the gut) feeds, often delivered through feeding tubes if the baby still cannot suck or swallow.

5 Sep 2018

Biophysicists propose new way to identify crucial factors for protein folding

A protein's folding patterns help them perform their dedicated tasks. As the real "doers" of the cell, even a tiny alteration in a protein's amino acid backbone can cause misfolding and hinder the protein's functionality or cause disease.

5 Sep 2018

Mechanical properties of viral DNA influence the course of infection, study finds

A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said.

5 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Scientists receive $2.5 million grant to combat South American-borne deadly disease

A George Mason University researcher is heading a scientific team that has received a sizable Department of Defense grant to combat the threat of a South American-borne disease that can cause long-term neurological problems and even death.

5 Sep 2018

Researchers discover how a protein complex safeguards against certain brain tumors

Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them.

5 Sep 2018

Research uncovers new mechanism involved in bone formation

Osteoporosis is a disease that causes bones to fracture easily due to a reduction in both bone mass and quality. Aging is one of its leading causes, and it is estimated that around 200 million people are affected worldwide.

5 Sep 2018

New strategy shows promise to tap earliest Alzheimer's changes in the brain

Finding an effective way to identify people with mild cognitive impairment who are most likely to go on to develop Alzheimer's disease has eluded researchers for years.

4 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Researchers discover key aspect in pathogenesis of multiple sclerosis

A team of researchers the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain.

4 Sep 2018

Scientists discover ALS disease mechanism

A mechanism for how the disease ALS evolves has been discovered at Umeå University, Sweden. The discovery concerns how proteins with a defect structure spread the deformation to other proteins. This according to results in a new thesis.

4 Sep 2018

CSIRO project seeks to clear the air over potentially life-saving noble gases

Australia’s national science agency, CSIRO, partnered with world leader in medical gases, Air Liquide Healthcare, to reveal how the noble gases’ interactions with proteins could one day be used to treat a variety of health issues.

4 Sep 2018

Study provides absolute 10-year estimates for dementia by age, sex and APOE genotype

A Danish study provides 10-year absolute risk estimates for dementia specific to age, sex and common variation in the APOE gene, which may help identify high-risk individuals who potentially could benefit from early targeted prevention.

4 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts.

4 Sep 2018

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Anaplastic large-cell lymphomas are rare cancers of the white blood cells. New research from the international ERIA consortium, led by scientists in Vienna, has now shown that the same signaling pathway is essential to the growth of cancer cells in various forms of ALCL: TYK2 (tyrosine kinase 2, an important component of the immune system) prevents apoptotic cell death by increasing the production of Mcl1, a special type of protein belonging to the BCL2 family.

3 Sep 2018

Protein C News and Research

Researchers hope to translate mRNA drugs from lab to medicine cabinet

Researchers make discovery about yeast metabolism that could help drug developers

New method may speed up development of novel drugs

Hypertension drugs may be used to preserve memory of lupus patients

Study finds ways to maximize nutrition and growth for tiniest of premature infants

Biophysicists propose new way to identify crucial factors for protein folding

Mechanical properties of viral DNA influence the course of infection, study finds

Tipping the scales to initiate tumorigenesis in the colon

Scientists receive $2.5 million grant to combat South American-borne deadly disease

Researchers discover how a protein complex safeguards against certain brain tumors

Research uncovers new mechanism involved in bone formation

New strategy shows promise to tap earliest Alzheimer's changes in the brain

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

Researchers discover key aspect in pathogenesis of multiple sclerosis

Scientists discover ALS disease mechanism

CSIRO project seeks to clear the air over potentially life-saving noble gases

Study provides absolute 10-year estimates for dementia by age, sex and APOE genotype

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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