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Diversity of gut bacteria may affect brain health

The surprising and potentially wide-ranging effects that the levels and diversity of bacteria living in the gut have on overall human health, inflammation, and specifically brain health are the focus of a provocative interview with Dr. David Perlmutter in Alternative and Complementary Therapies, a journal from Mary Ann Liebert, Inc., publishers.

11 Jul 2016

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

In September 2014, President Obama issued an executive order for "Combating Antibiotic- Resistant Bacteria." Why the urgency? The Centers for Disease Control and Prevention, the order noted, "estimates that annually at least 2 million illnesses and 23,000 deaths are caused by antibiotic- resistant bacteria in the United States alone."

11 Jul 2016

High frequency of alleles could increase risk of lupus in non-Europeans

Non-Europeans have a higher frequency of the gene variants that increase the risk of lupus as compared to the European population, a new study from researchers at the National Institute for Health Research Biomedical Research Centre at Guy's and St Thomas' and King's College London, has confirmed.

11 Jul 2016

New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss.

11 Jul 2016

UChicago to help enroll 150,000 participants in President’s PMI Cohort Program

The University of Chicago is one of three Illinois academic institutions that will work together to help launch President Obama's Precision Medicine Initiative Cohort Program to enroll 1 million or more participants in a national research effort designed to find better ways to prevent and treat disease based on lifestyle, environment and genetics.

11 Jul 2016

NIH selects VUMC to play foundational role in PMI Cohort Program

Vanderbilt University Medical Center has been chosen by the National Institutes of Health to be the Data and Research Support Center for the Precision Medicine Initiative Cohort Program, a landmark study of genetic, environmental and lifestyle factors affecting the health of a million or more people, federal officials have announced.

11 Jul 2016

Five-year NIH grant awarded to four NYC medical centers for PMI Cohort Program

Columbia University Medical Center and Weill Cornell Medicine, in collaboration with NewYork-Presbyterian and NYC Health + Hospitals/Harlem, have been awarded a grant from the NIH for approximately $4 million in fiscal year 2016 to enroll participants in the Cohort Program of President Barack Obama's Precision Medicine Initiative (PMI)—a large-scale research effort to improve our ability to prevent and treat disease based on individual differences in lifestyle, environment and genetics.

11 Jul 2016

AMP looks forward to working with FDA to determine optimal approach to regulating NGS tests

The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostic professionals, today announced that it looks forward to working with the U.S. Food and Drug Administration to determine the best adaptive approach to regulating Next-Generation Sequencing (NGS) tests.

11 Jul 2016

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don't just disappear. They wind up in the blood stream, where degraded bits and pieces can be extracted.

8 Jul 2016

Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer

Cancer is a group of more than 100 different diseases. All are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body.

8 Jul 2016

TSRI researchers link genes within striatum to bipolar disorder

While bipolar disorder is one of the most-studied neurological disorders—the Greeks noticed symptoms of the disease as early as the first century—it’s possible that scientists have overlooked an important part of the brain for its source.

8 Jul 2016

Researchers uncover role for Wars2 gene in angiogenesis process

In a study conducted by Duke-NUS Medical School and the National Heart Centre Singapore, researchers discovered a new gene that controls blood vessel formation.

8 Jul 2016

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified a set of genes, including DNMT3A, that could potentially be used to predict clinical outcomes of patients who suffer from a type of Acute Myeloid Leukemia (AML) associated with an FLT3 internal tandem duplication (FLT3-ITD) mutation.

8 Jul 2016

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Great strides have been made in treating neuroblastoma, the most common cancer in infants and toddlers. However, advanced cases are often fatal, and children who survive often face life-long physical and intellectual challenges related to their treatment.

8 Jul 2016

Germline genetic testing necessary for men with metastatic prostate cancer

Men with metastatic prostate cancer should be considered for germline genetic testing of DNA repair genes, regardless of age or family history, according to a team of researchers from Memorial Sloan Kettering Cancer Center, Fred Hutchinson Cancer Research Center, Dana-Farber Cancer Institute, University of Washington School of Medicine, University of Michigan, and the Institute of Cancer Research Royal Marsden Hospital.

8 Jul 2016

Researchers develop DNA-based nanomachine to detect variety of substances

Researchers at McMaster University have established a way to harness DNA as the engine of a microscopic "machine" they can turn on to detect trace amounts of substances that range from viruses and bacteria to cocaine and metals.

8 Jul 2016

Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

Investigators at Beth Israel Deaconess Medical Center have identified a developmental cause of adult-onset cardiac hypertrophy, a dangerous thickening of the heart muscle that can lead to heart failure and death.

8 Jul 2016

TSRI awarded $20 million for first year of precision medicine initiative cohort program

As part of the most ambitious medical research program in the history of American medicine, The Scripps Research Institute (TSRI) has received an initial award of $20 million for its role in a national precision medicine initiative, the National Institutes of Health (NIH) announced today.

8 Jul 2016

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery.

7 Jul 2016

New genetic test provides rapid diagnosis of mitochondrial disease

Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene.

7 Jul 2016

Genetic News and Research

Diversity of gut bacteria may affect brain health

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

High frequency of alleles could increase risk of lupus in non-Europeans

New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

UChicago to help enroll 150,000 participants in President’s PMI Cohort Program

NIH selects VUMC to play foundational role in PMI Cohort Program

Five-year NIH grant awarded to four NYC medical centers for PMI Cohort Program

AMP looks forward to working with FDA to determine optimal approach to regulating NGS tests

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer

TSRI researchers link genes within striatum to bipolar disorder

Researchers uncover role for Wars2 gene in angiogenesis process

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Germline genetic testing necessary for men with metastatic prostate cancer

Researchers develop DNA-based nanomachine to detect variety of substances

Study identifies genetic mutations responsible for development of cardiac hypertrophy in adults

TSRI awarded $20 million for first year of precision medicine initiative cohort program

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

New genetic test provides rapid diagnosis of mitochondrial disease

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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