G Protein News and Research

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Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007

Scientists show protein accelerates breast cancer progression in animal models

The study is being published in an advanced online edition of the Proceedings of the National Academy of Sciences.

23 Jun 2007

Goltz syndrome gene found

Researchers funded in part by the National Institutes of Health have identified the gene that accounts for most cases of Goltz syndrome, a rare skin disorder that can also affect bone and eye development.

23 Jun 2007

Key mechanism identified by which the body regulates iron metabolism

Scientists at the University of California, San Diego (UCSD) have determined a key mechanism by which the body regulates iron metabolism, a discovery that may provide new approaches for the treatment of anemia.

23 Jun 2007

Entecavir can compromise HIV treatment

Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal, according to a new report in the New England Journal of Medicine.

23 Jun 2007

Autism-related proteins control nerve excitability

Two proteins that are implicated in autism have been found to control the strength and balance of nerve-cell connections, researchers at UT Southwestern Medical Center have found.

23 Jun 2007

Autistic boys have high levels of growth hormones

Boys with autism and autism spectrum disorder had higher levels of hormones involved with growth in comparison to boys who do not have autism, reported researchers from the National Institutes of Health, the Centers for Disease Control and Prevention, the Cincinnati Children's Hospital and the University Of Cincinnati College Of Medicine.

22 Jun 2007

PepTcell vaccine could provide immunity against all strains of influenza virus

Previously undisclosed pre-clinical data showing how a new flu vaccine has the potential to protect against all strains of influenza, including pandemic and annual, was presented by PepTcell, at the 2007 Options for the Control of Influenza VI (Options) Conference, in Toronto, Canada.

20 Jun 2007

Scientists develop unique “switch” that can control the activity of any protein

Our bodies could not maintain their existence without thousands of proteins performing myriad vital tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders.

20 Jun 2007

New uderstanding of how enzymes work

In a publication selected as a "2007 Hot Article" by the journal Biochemistry , University at Buffalo chemists report the discovery of a central mechanism responsible for the action of the powerful biological catalysts known as enzymes.

20 Jun 2007

Low carb diets lower levels of good bacteria in gut

Scientists at Aberdeen's Rowett Research Institute have shown that a very low carbohydrate weight-loss diet results in a four-fold reduction in the numbers of certain types of bacteria in the gut of obese men.

20 Jun 2007

Acquired DNA key to certain bacterial infection

Researchers announced this week the discovery of a mechanism by which Mycobacterium avium - a bacterium which can result in serious lung infections and is prevalent in emphysema and AIDS patients among others - infects tissue cells or macrophages and thus compromises the body's immunity.

19 Jun 2007

New target for therapies for retinopathy

A protein long thought to be one of the body's supporting players has quietly been taking a lead role in healthy eyesight, a discovery that could rapidly lead to treatments for babies born before their eyes are finished growing, University of Florida and Harvard Medical School researchers have found.

19 Jun 2007

PINK1 protects from Parkinson's

Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons.

19 Jun 2007

Faster, less expensive technique for mutating large, non-gene stretches of DNA

Genes account for only 2.5 percent of DNA in the human genetic blueprint, yet diseases can result not only from mutant genes, but from mutations of other DNA that controls genes.

19 Jun 2007

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

19 Jun 2007