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Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

IQWiG assesses potential of MRI-guided high-intensity focused ultrasound therapy for uterine fibroids

For the first time since the corresponding law became effective in 2012, the German Institute for Quality and Efficiency in Health Care has published an assessment of the potential of a new treatment method according to §137e of Social Code Book V.

23 Mar 2017

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice.

23 Mar 2017

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer's disease (AD), based upon genetic information.

22 Mar 2017

Study identifies urinary biomarker that may help monitor progression of ALS

A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with amyotrophic lateral sclerosis (ALS) may help monitor disease progression as well as determine the effectiveness of therapies.

22 Mar 2017

UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Two landmark publications with one or more co-authors from the University of Cincinnati Gardner Neuroscience Institute outline a transformative approach to defining, studying and treating Parkinson's disease.

22 Mar 2017

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

A Phase I clinical trial that targeted individuals with new onset paraplegia to evaluate the safety of transplanting their own potentially neuroprotective Schwann cells into a trauma-induced spinal cord lesion showed no evidence of adverse effects after 1 year.

22 Mar 2017

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

For parents, storing their newborn baby's umbilical cord blood is a way to preserve potentially lifesaving cells. Now, a group of University of Florida Health researchers has found a way to expand and preserve certain cord-blood cells as a potential treatment for Type 1 diabetes.

22 Mar 2017

RUB researchers identify new rare muscle disorder

A new rare muscle disorder has been identified by researchers at Ruhr-Universität Bochum. This hereditary disease is caused by a defect in the BICD2 gene that manifests itself in altered cellular transport processes in skeletal muscle cells.

22 Mar 2017

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

Royal Philips today announced that the results from two large clinical trials comparing patient outcomes using instant wave-free ratio (iFR) and fractional flow reserve (FFR) in the diagnosis and treatment of heart disease have been published in the New England Journal of Medicine.

From Philips Healthcare 22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

Direct-to-consumer ‘low-T’ medication advertising increases prescriptions but may not improve health

Direct-to-consumer advertising for drugs to treat testosterone deficiency -- or "low T" -- increases prescriptions to men for hormone-replacement therapies but may not improve their health, UC Davis physician Richard Kravitz said in an editorial published in the March 21 issue of the Journal of the American Medical Association.

22 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

ECDC guidance aims to improve antenatal screening for infections to avoid mother-to-child transmission

Transmission of infections with HIV, hepatitis B, syphilis or rubella from mother to child before and during birth as well as in infancy still occur across Europe - despite existing prevention methods.

21 Mar 2017

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy.

21 Mar 2017

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Chemists from Russia and Switzerland created biosafe luminescent nanoparticles for imaging tumors and blood vessels damaged by heart attack or stroke.

21 Mar 2017

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with clinically guided dosing, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

21 Mar 2017

Therapy News and Research

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

IQWiG assesses potential of MRI-guided high-intensity focused ultrasound therapy for uterine fibroids

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

Study identifies urinary biomarker that may help monitor progression of ALS

UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

RUB researchers identify new rare muscle disorder

Philips announces results from clinical studies comparing iFR- and FFR-guided strategy for assessment of heart disease

Changes in the vascular system could play role in initiating Alzheimer’s disease

Direct-to-consumer ‘low-T’ medication advertising increases prescriptions but may not improve health

Study identifies potential Achilles heel of kinase-driven cancers

ECDC guidance aims to improve antenatal screening for infections to avoid mother-to-child transmission

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Research findings hold promise to generate blood cell precursors from hPSCs

New study provides insights into strengths and vulnerabilities of couples raising child with ASD

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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