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Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.

3 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

Immune-stimulating chemical found in tumors may help stop cancer growth

A chemical found in tumors may help stop tumor growth, according to a new study.

2 Mar 2017

Workers without paid sick leave less likely to receive preventive health care screenings, study finds

More than 20 million Americans have gained health insurance coverage through the Affordable Care Act and do not have to pay for 15 preventive screenings recommended by the U.S. Preventive Services Task Force.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Duke researchers use new technique for assessing cancer cell's stiffness

Biomedical engineers at Duke University have discovered a way to detect signs of cancer on a cell-by-cell basis using two lasers and a camera.

1 Mar 2017

AGA creates Obesity Practice Guide for effective weight management in obese patients

Patients with obesity need a multidisciplinary approach to achieve a healthy weight, and the American Gastroenterological Association (AGA) believes that gastroenterologists are in a unique position to lead the care team.

28 Feb 2017

KRAS ‘imbalances’ that emerge over time may influence cancer treatment response

Choosing among cancer treatments increasingly involves determining whether tumor cells harbor specific, mutated "oncogenes" that drive abnormal growth and that may also be especially vulnerable or resistant to particular drugs.

28 Feb 2017

Yale researchers explore how aggressive LUAD cells manage to grow outside the lungs

More people die of lung cancer each year than breast, colon, and prostate cancers combined. One particularly lethal form of the disease is lung adenocarcinoma or LUAD, which afflicts both smokers and non-smokers.

28 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well as a marker that may predict response to a particular class of drugs, not just in patients with thyroid cancer, but in those with many other types of cancer as well.

21 Feb 2017

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

A new study led by researchers at Beth Israel Deaconess Medical Center has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis, an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the colon.

17 Feb 2017

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

New research shows that nearly three-quarters of patients with moderate to severe ulcerative colitis (UC) taking conventional treatments describe their disease as ‘poorly controlled’ (continuous or regular experience of symptoms that negatively affect quality of life), with half saying they are somewhat or completely dissatisfied with their current medication; only 1% were completely satisfied with their current treatment.

17 Feb 2017

Targeting biological clock in cancer cells could inhibit tumour growth

Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in McGill University's Department of Psychiatry.

16 Feb 2017

Radiotherapy for breast cancer linked to greater risk of second primary lung cancer

East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer.

16 Feb 2017

HCI researchers uncover how epithelial cells naturally turn over to maintain constant numbers

Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell division and cell death.

15 Feb 2017

Research opens treatment pathways for cancers that do not respond to targeted antibodies

By hijacking a cancer cell's own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule sugars. This opens treatment pathways for cancers that are not responsive to conventional targeted antibodies, such as triple-negative breast cancer.

15 Feb 2017

Study discovers how gut bacteria interacts with microRNAs to promote colon cancer growth

Gut microbes can influence the growth of colon cancer, though little is known about how they trigger the disease.

14 Feb 2017

Scientists identify new biomarkers that could guide bowel cancer treatment

Colorectal carcinomas arise in different forms, so all treatments do not work for all patients. OncoTrack, a public-private consortium supported by the Innovative Medicines Initiative Joint Undertaking, has conducted one of Europe's largest collaborative academic-industry research projects to develop and assess novel approaches for identification of new markers for colon cancer.

13 Feb 2017

Professor aims to develop shortcuts for targeted and effective cancer therapy

The aim is to identify precisely the one drug, or the correct combination of drugs, that are most effective against the specific tumor present in each patient. Professor hopes that new tools will come into use in the next five years.

13 Feb 2017

Colon News and Research

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Immune-stimulating chemical found in tumors may help stop cancer growth

Workers without paid sick leave less likely to receive preventive health care screenings, study finds

Using Spherical Nucleic Acids to Track and Treat Disease

Duke researchers use new technique for assessing cancer cell's stiffness

AGA creates Obesity Practice Guide for effective weight management in obese patients

KRAS ‘imbalances’ that emerge over time may influence cancer treatment response

Yale researchers explore how aggressive LUAD cells manage to grow outside the lungs

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

Targeting biological clock in cancer cells could inhibit tumour growth

Radiotherapy for breast cancer linked to greater risk of second primary lung cancer

HCI researchers uncover how epithelial cells naturally turn over to maintain constant numbers

Research opens treatment pathways for cancers that do not respond to targeted antibodies

Study discovers how gut bacteria interacts with microRNAs to promote colon cancer growth

Scientists identify new biomarkers that could guide bowel cancer treatment

Professor aims to develop shortcuts for targeted and effective cancer therapy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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