Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

World expert panel recommends routine brain health screening for adults older than 70

A panel of world experts in aging convened at Saint Louis University recommended that everyone 70 and older should have their memory and reasoning ability evaluated annually by a doctor or health care provider.

10 Sep 2015

New trial results show efficacy of novel enzyme-replacement therapy for genetic lipid disorder

Of the more than 50 known lysosomal storage diseases (LSDs)-rare inherited metabolic disorders-only seven can be treated with approved enzyme-replacement therapies.

10 Sep 2015

CHAM, AECC receive $1.3 million NCI grant to advance more effective bone cancer treatments for children

The Children's Hospital at Montefiore and the NCI-designated Albert Einstein Cancer Center today announced receipt of $1.3 million grant from the National Cancer Institute, part of the National Institutes of Health.

9 Sep 2015

AMRA, Pfizer collaborate to assess fat and muscle measurements to predict obesity, diabetes

AMRA announced that they have entered into a unique international collaboration with Pfizer Inc. to investigate the relationship between fat and muscle distribution in the body and metabolic health, including risk factors for conditions such as obesity and diabetes.

8 Sep 2015

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Some treatments for type 2 diabetes make the body more sensitive to insulin, the hormone that lowers blood sugar. But new research at Washington University School of Medicine in St. Louis suggests a different strategy: slowing the production of glucose in the liver.

4 Sep 2015

Risk score predicts ACLF risk in chronic HBV patients

A risk score incorporating routinely collected clinical information can identify patients with chronic hepatitis B virus infection at high risk of developing acute-on-chronic liver failure following severe acute exacerbation, research suggests.

3 Sep 2015

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct adverse health effect on the liver and causes liver fibrosis, an illness associated with metabolic disease and liver cancer.

3 Sep 2015

TGen scientists identify potential gene associated with NAFLD-related liver damage

In a first-of-its-kind exploratory study, the Translational Genomics Research Institute has identified a potential gene associated with the initiation of the most common cause of liver damage.

2 Sep 2015

New NIH grants support research that combines DNA sequence information and electronic medical records

A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.

2 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

SLU study finds that length of stay in ED makes no real difference in mortality of trauma patient

The amount of time a trauma patient stays in the emergency department (ED) makes no real difference in the patient's mortality, researchers at Saint Louis University found in a recent study.

28 Aug 2015

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Liver transplantation is currently the only established treatment for patients with end stage liver failure. However, this treatment is limited by the shortage of donors and the conditional integrity and suitability of the available organs. Transplanting donor hepatocytes (liver cells) into the liver as an alternative to liver transplantation also has drawbacks as the rate of survival of primary hepatocytes is limited and often severe complications can result from the transplantation procedure.

27 Aug 2015

Yale study identifies new barrier to caring for chronic hepatitis C patients

Nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection, according to a Yale School of Medicine study.

27 Aug 2015

High dietary iron intake suppresses hormone that regulates appetite

Here's one more reason to cut down on the amount of red meat you eat. Using an animal model, researchers at Wake Forest Baptist Medical Center have found that dietary iron intake, equivalent to heavy red meat consumption, suppresses leptin, a hormone that regulates appetite.

25 Aug 2015

Older people drink unsafe amounts of alcohol, study finds

One in five older people who drink alcohol are consuming it at unsafe levels - over 21 units of alcohol for men and 14 units for women each week - according to a study by King's College London. The research in inner-city London, published in BMJ Open, found these unsafe older drinkers are more likely to be of higher socioeconomic status.

24 Aug 2015

Liver Disease News and Research

Further Reading

World expert panel recommends routine brain health screening for adults older than 70

New trial results show efficacy of novel enzyme-replacement therapy for genetic lipid disorder

CHAM, AECC receive $1.3 million NCI grant to advance more effective bone cancer treatments for children

AMRA, Pfizer collaborate to assess fat and muscle measurements to predict obesity, diabetes

Inhibiting key protein involved in glucose production may help in treating type 2 diabetes

Risk score predicts ACLF risk in chronic HBV patients

Inhalation exposure to PM2.5 pollution triggers liver fibrosis

TGen scientists identify potential gene associated with NAFLD-related liver damage

New NIH grants support research that combines DNA sequence information and electronic medical records

SLU scientist receives grant to solve blood-clotting mysteries

SLU study finds that length of stay in ED makes no real difference in mortality of trauma patient

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Yale study identifies new barrier to caring for chronic hepatitis C patients

High dietary iron intake suppresses hormone that regulates appetite

Older people drink unsafe amounts of alcohol, study finds

New data shows liver cancer has significantly increased in Queensland since the mid-90s

Researchers identify strategy to prevent adenoviruses from multiplying and causing sickness in humans

Breath test for liver disease detection moves closer

SLUCare cardiac surgeon aims to connect underserved population in St. Louis region with health care services

New study offers first clinical recommendations for headache diagnosis in pregnant women

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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