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Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia - the brain's immune cells - can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

3 Jan 2024

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Scientists link growth hormone to anxiety and fear memory through specific neuron group

Growth hormone (GH) acts on many tissues throughout the body, helping build bones and muscles, among other functions.

2 Jan 2024

Exploring fear engrams to shed light on physical manifestation of memory in the brain

In a world grappling with the complexities of mental health conditions like anxiety, depression, and PTSD, new research from Boston University neuroscientist Dr. Steve Ramirez and collaborators offers a unique perspective.

2 Jan 2024

Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

Study reveals novel neural coding mechanism for transferring perceptual information to memory

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.

2 Jan 2024

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

Scientists at the Johns Hopkins University School of Medicine and the National Institutes of Health have identified a protein in the visual system of mice that appears to be key for stabilizing the body's circadian rhythms by buffering the brain's response to light.

28 Dec 2023

Hackensack Meridian's Dr. Mary Sedarous wins ALS United Mid-Atlantic's Flame of Hope Award

Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center's Mary Sedarous, M.D., medical director of the ALS Center, was honored at ALS United Mid-Atlantic's 2023 Annual Celebration with the organization's Flame of Hope Award, recognizing research and innovation.

26 Dec 2023

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

There does not appear to be any profound differences between so-called exposure-based CBT and traditional CBT in the treatment of fibromyalgia, according to a study led by researchers at Karolinska Institutet.

22 Dec 2023

Examining two serum biomarkers as early predictors of cognitive decline in women

Researchers from the University of Michigan have connected two blood biomarkers to changes in cognitive function in women in midlife, opening a potentially powerful path to noninvasive, earlier detection and interventions for Alzheimer’s disease and other dementias.

21 Dec 2023

Unraveling nuanced roles of JAK inhibitors in inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

21 Dec 2023

Football linked to more brain damage beyond white matter marks

Signs of injury to the brain's white matter called white matter hyperintensities, as seen on brain scans, may be tied more strongly to vascular risk factors, brain shrinkage, and other markers of dementia in former tackle football players than in those who did not play football, according to a study published in the December 20, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Dec 2023

Study reveals brain's built-in mechanism for stitching experiences into memories

Scientists at NTNU's Kavli Institute for Systems Neuroscience in Norway have discovered a pattern of activity in the brain that serves as a template for building sequential experiences.

20 Dec 2023

OSU study pinpoints early muscle loss mechanism in acute spinal cord injury

Acute spinal cord injury (SCI) patients lose body weight and muscle mass, despite being on a high-calorie diet while in the intensive care unit.

20 Dec 2023

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich School of Arts and Sciences.

20 Dec 2023

Neuroscience News and Research

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

"Genetic priority score" promises to revolutionize drug development

Scientists link growth hormone to anxiety and fear memory through specific neuron group

Exploring fear engrams to shed light on physical manifestation of memory in the brain

Brain receptor discovery opens door to new therapies for addiction and mental health

Study reveals novel neural coding mechanism for transferring perceptual information to memory

'Visual system' protein appears to be key for stabilizing the body's circadian rhythms

Hackensack Meridian's Dr. Mary Sedarous wins ALS United Mid-Atlantic's Flame of Hope Award

Fox urine compound effectively repels flies through multisensory activation

Brain injury markers found in the blood months after COVID-19 infection

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

Examining two serum biomarkers as early predictors of cognitive decline in women

Unraveling nuanced roles of JAK inhibitors in inflammation

Football linked to more brain damage beyond white matter marks

Study reveals brain's built-in mechanism for stitching experiences into memories

OSU study pinpoints early muscle loss mechanism in acute spinal cord injury

UW-Madison technology unveils autism gene's impact on early brain structure

Study reveals extensive postnatal neuronal migration in human entorhinal cortex

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