Genetic News and Research

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Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

Scientists identify potential drug target that disrupts Zika and similar viruses

Scientists potentially have found a way to disrupt Zika and similar viruses from spreading in the body.

17 Jun 2016

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Researchers from the 'Angiogenesis signaling pathways' research group of the Institute of Biomedical Investigation of Bellvitge, led by Dr. Mariona Graupera, have unveiled the potential therapeutic benefit of a selective inhibitior of the PI3-kinase (PI3K) protein in pancreatic neuroendocrine tumors (PanNETs).

17 Jun 2016

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions.

17 Jun 2016

Delayed healing linked to weaker electrical currents in diabetic wounds

People with diabetes often suffer from wounds that are slow to heal and can lead to ulcers, gangrene and amputation. New research from an international group led by Min Zhao, professor of ophthalmology and of dermatology at the University of California, Davis, shows that, in animal models of diabetes, slow healing is associated with weaker electrical currents in wounds.

17 Jun 2016

New collaborative research program connects canine and human cancers

A new collaborative research program pairs oncologists who treat childhood and adult sarcomas with veterinarians who manage the same cancers in canine patients.

17 Jun 2016

Caribbean, African-born women more likely to be admitted at ICU during delivery

Women born in the Caribbean or Africa are two times more likely to be admitted to an intensive care unit at the time of their delivery than Canadian-born women, a new study has found.

17 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets.

17 Jun 2016

Mice study highlights vital role of liver in balancing fats and sugars

Sugar in the form of blood glucose provides essential energy for cells. When its usual dietary source — carbohydrates — is scarce, the liver can produce it with the aid of fat.

17 Jun 2016

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells.

17 Jun 2016

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1-phosphate (S1P), which is linked to MS pathogenesis.

16 Jun 2016

Scientists identify lipodystrophy-causing mutation in a single family

Lipodystrophy syndromes are characterized by an abnormal distribution of adipose tissue and metabolic dysfunction. These disorders are rare and the underlying genetic abnormalities that lead to altered fat distribution are not fully known.

16 Jun 2016

Researchers clarify cause of heart arrhythmia in myotonic dystrophy

An international joint research group found that the cause of heart arrhythmia in myotonic dystrophy was RNA abnormalities in the sodium channel in the heart, clarifying the symptom's mechanism. This finding will be helpful in prevention and early intervention of death in this disease, leading to the development of new treatment.

16 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

"Loss is nothing else but change and change is nature's delight" says the quote by the philosopher and emperor Marcus Aurelius, which opens the scientific article that analyses the gene loss phenomenon and its impact on the evolution of living beings.

16 Jun 2016

Research suggests gonad as vital player in evolutionary process

A pair of studies led by Indiana University researchers provide new evidence that when it comes to evolution, the testes may play a key role.

16 Jun 2016

Innovative computer HIV capsid model provides real insight into virus maturation process

From a virus's point of view, invading our cells is a matter of survival. The virus makes a living by highjacking cellular processes to produce more of the proteins that make it up.

16 Jun 2016

New superbug test developed by TGen-NAU receives Australian patent

Antibiotic-resistant infections should be easier to detect, and hospitals could become safer, thanks to a technology developed by the Translational Genomics Research Institute and Northern Arizona University, and protected under a patent issued by Australia.

16 Jun 2016

Penn researchers help identify unique characteristics of reserve stem cells

Adult stem cells represent a sort of blank clay from which a myriad of different cell and tissue types are molded and as such are of critical importance to health, aging and disease.

16 Jun 2016

Genetic News and Research

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Scientists identify potential drug target that disrupts Zika and similar viruses

Researchers uncover potential therapeutic benefit of PI3K protein in PanNETs

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Delayed healing linked to weaker electrical currents in diabetic wounds

New collaborative research program connects canine and human cancers

Caribbean, African-born women more likely to be admitted at ICU during delivery

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

Mother's obesity can impair health of future generations

Mice study highlights vital role of liver in balancing fats and sugars

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

S1P1R variation may cause differential patient responses to fingolimod treatment

Scientists identify lipodystrophy-causing mutation in a single family

Researchers clarify cause of heart arrhythmia in myotonic dystrophy

Scientists develop new software program that can help compare large amounts of metagenomes

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

Research suggests gonad as vital player in evolutionary process

Innovative computer HIV capsid model provides real insight into virus maturation process

New superbug test developed by TGen-NAU receives Australian patent

Penn researchers help identify unique characteristics of reserve stem cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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