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Beta blockers reverse potentially detrimental genetic changes linked to heart disease

Beta blockers are commonly used world-wide to treat a variety of cardiovascular conditions, such as arrhythmias and heart failure.

30 Jun 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

Mitochondria-targeted antioxidant shows promise for diabetic wound treatment

Members of the Faculty of Biology and A.N. Belozersky Institute of Physico-Chemical Biology, a unit of the Lomonosov Moscow State University, have tested on a mouse model a mitochondria-targeted antioxidant, helping to treat diabetic wounds.

29 Jun 2017

Opioid use disorder rises with little being done to curb the menace says new study

A new study has found that more and more Americans are being diagnosed with opioid addiction and the numbers that receive treatment are still very few. This finding is consistent with earlier findings from Blue Cross Blue Shield when analyzing member data.

29 Jun 2017

FDA to expedite orphan drug processing queues

In a press release the U.S. Food and Drug Administration (FDA) released a plan for eliminating the backlog regarding orphan drug application status and also released plans for deadlines to clear the queues.

29 Jun 2017

FDA authorizes marketing of test to aid in diagnoses of serious cancers

The U.S. Food and Drug Administration today allowed marketing of ClearLLab Reagents (T1, T2, B1, B2, M), the first agency authorized test for use with flow cytometry to aid in the detection of several leukemias and lymphomas, including chronic leukemia, acute leukemia, non-Hodgkin lymphoma, myeloma, myelodysplastic syndrome (MDS) and myeloproliferative neoplasms (MPN).

29 Jun 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

New therapeutic approach offers hope for individuals with debilitating bone cancer

An Australian-led research team has demonstrated a new therapeutic approach that can re-build and strengthen bone, offering hope for individuals with the debilitating bone cancer, multiple myeloma.

29 Jun 2017

Study finds link between new opioid use and increased risk of cardiac death in older adults with COPD

Older adults with chronic obstructive pulmonary disorder who recently started using opioids have an increased risk of coronary artery disease-related death compared to non-opioid users, researchers at St. Michael's Hospital have found.

29 Jun 2017

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Nicole F. Steinmetz, PhD, George J. Picha Professor in Biomaterials, member of the Case Comprehensive Cancer Center, and Director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

29 Jun 2017

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.

29 Jun 2017

Research yields first successful isolation, maintenance of haploid embryonic stem cells in humans

Stem cell research holds huge potential for medicine and human health. In particular, human embryonic stem cells (ESCs), with their ability to turn into any cell in the human body, are essential to the future prevention and treatment of disease.

29 Jun 2017

Simple treatment leads to sustained virological response in patients with thalassaemia and HCV

Many individuals with the blood disorder thalassaemia also carry the hepatitis C virus (HCV) due to contaminated transfusions before 1990.

29 Jun 2017

Large-scale lung cancer screening for high-risk people could be economically viable, research shows

Lung cancer screening is likely to be cost-effective, particularly if it also identifies other tobacco-related conditions in high-risk people, suggests new research published in the Journal of Thoracic Oncology.

29 Jun 2017

Psychological tools help high-risk chronic pain patients to taper opioid use

Psychological support and new coping skills are helping patients at high risk of developing chronic pain and long-term, high-dose opioid use taper their opioids and rebuild their lives with activities that are meaningful and joyful to them.

29 Jun 2017

Adding new antibody to chemotherapy could bolster effects of cancer treatment

Adding an investigational antibody to the chemotherapy rituximab appears to restore its cancer-killing properties in certain leukemia patients with a natural resistance to the drug, according to a small, proof-of-concept study by Duke Cancer Institute researchers.

29 Jun 2017

Researchers suggest new strategy to identify germline mutations in men with prostate cancer

Scientists have had limited success at identifying specific inherited genes associated with prostate cancer, despite the fact that it is one of the most common non-skin cancers among men.

29 Jun 2017

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs.

28 Jun 2017

Injecting plant-based nanoparticles and chemotherapy drug helps halt tumor progression in mice

Researchers from Case Western Reserve University School of Medicine in collaboration with researchers from Dartmouth Geisel School of Medicine and RWTH Aachen University have adapted virus particles- that normally infect potatoes- to serve as cancer drug delivery devices for mice.

28 Jun 2017

PNNL-OHSU scientists part of NCI effort to study about role of proteins in cancer biology

The Department of Energy's Pacific Northwest National Laboratory is part of a nationwide effort to learn more about the role of proteins in cancer biology and to use that information to benefit cancer patients.

28 Jun 2017

Drugs News and Research

Beta blockers reverse potentially detrimental genetic changes linked to heart disease

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

Mitochondria-targeted antioxidant shows promise for diabetic wound treatment

Opioid use disorder rises with little being done to curb the menace says new study

FDA to expedite orphan drug processing queues

FDA authorizes marketing of test to aid in diagnoses of serious cancers

New antiviral drug candidate effective against broad range of coronaviruses

New therapeutic approach offers hope for individuals with debilitating bone cancer

Study finds link between new opioid use and increased risk of cardiac death in older adults with COPD

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Research yields first successful isolation, maintenance of haploid embryonic stem cells in humans

Simple treatment leads to sustained virological response in patients with thalassaemia and HCV

Large-scale lung cancer screening for high-risk people could be economically viable, research shows

Psychological tools help high-risk chronic pain patients to taper opioid use

Adding new antibody to chemotherapy could bolster effects of cancer treatment

Researchers suggest new strategy to identify germline mutations in men with prostate cancer

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

Injecting plant-based nanoparticles and chemotherapy drug helps halt tumor progression in mice

PNNL-OHSU scientists part of NCI effort to study about role of proteins in cancer biology

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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