Genetic News and Research

RSS

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

Black men with high degree of West African genetic ancestry have less central adiposity

Among black men, those with more genetic variants descended from West Africa may have a relatively lower risk of being overweight, obese and diabetic, according to a new study out of the University of Alabama at Birmingham and University of Arizona.

2 Jun 2016

New technique could help reduce chances of drug failure during later stages of clinical trials

An approach that could reduce the chances of drugs failing during the later stages of clinical trials has been demonstrated by a collaboration between the University of Cambridge and pharmaceutical company GlaxoSmithKline.

2 Jun 2016

BRCA gene mutations raise risk of breast, ovarian and other cancers

BRCA Share, a public-private BRCA gene datashare initiative, today announced the public release of a large collection of new data on genetic variants in the BRCA1 and BRCA2 genes.

From Quest Diagnostics 2 Jun 2016

Dr Anjali Mahto explains how to prevent risk of mosquito bites

Nobody likes being bitten by mosquitos whether it’s at home or abroad. Consultant Dermatologist & British Skin Foundation spokesperson, Dr Anjali Mahto explains how to deter the summer pests, what to do when bitten and why they are attracted to us in the first place.

2 Jun 2016

New mouse model offers more insight into development of ASD in humans

A new mouse model, developed by researchers at the University of Wisconsin-Madison, is the first to show that when more of a specific biological molecule moves between different parts of nerve cells in the mouse brain, it can lead to behaviors that resembles some aspects of autism spectrum disorder (ASD) in humans.

2 Jun 2016

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure.

2 Jun 2016

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease.

2 Jun 2016

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Researchers have discovered three new inhibitors of insulin-regulated aminopeptidase (IRAP), compounds shown to improve cognitive functions in animal models of human disorders.

2 Jun 2016

Correcting defective p73 gene function may be promising therapeutic strategy for chronic lung diseases

Rising global air pollution and increasing smoking prevalence in many developing nations will likely lead to a growing incidence of lung diseases such as chronic obstructive pulmonary disease (COPD), which currently affects more than 330 million people worldwide, is the third-leading cause of death and carries an estimated healthcare cost of $2.1 trillion.

2 Jun 2016

Buck researchers identify new, potential drug targets for sporadic PD

Research at the Buck Institute shows the same mechanisms that lead to neuronal cell death in mice genetically fated to develop Parkinson's disease (PD) are involved in the much more common sporadic form of the age-related, neurodegenerative disorder that robs people of the ability to move normally.

2 Jun 2016

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

People with Alzheimer's disease could benefit from earlier diagnosis if a long-term memory test combined with a brain scan were carried out, a study suggests.

1 Jun 2016

Recent research gives more insight into genetics of FASD

In 1973, a group of birth defects associated with prenatal ethanol exposure was clinically recognized as Fetal Alcohol Syndrome (FAS). Since then, scientists have come to realize that alcohol can cause a wide range of birth defects; these are collectively referred to as Fetal Alcohol Spectrum Disorders (FASD).

1 Jun 2016

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

An international team led by researchers at the Austrian Institute of Molecular Biotechnology in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. An already approved drug could be quickly available and would then be the first breast cancer prevention drug.

1 Jun 2016

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time created a drug candidate that attacks and neutralizes the RNA structure that causes an incurable progressive, inherited disease involving a gradual loss of control over body movement.

1 Jun 2016

Cigarette smoke promotes bacteria colonization, immune invasion

The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system.

1 Jun 2016

New research in mice provides better understanding of how HD begins and develops

Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.

1 Jun 2016

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

Cryptococcus is a fungus found in the environment throughout the world that is able to cause disease in humans. While most fungal pathogens don’t receive as much press as their bacterial or viral counterparts, they can be just as deadly.

1 Jun 2016

New study explores sexual assault victimization among bisexual, gay college students

A new study of sexual assault on college campuses found that nearly 2 of every 5 bisexual female college students experienced sexual assault after four years in college. About 1 in 4 gay and bisexual men are victims of sexual assault during college, which is similar to the frequency reported by heterosexual women, according to the study published in the journal Violence and Gender, from Mary Ann Liebert, Inc., publishers.

1 Jun 2016

Genetic News and Research

Retroviral replicating vector can extend lives of brain cancer patients

Black men with high degree of West African genetic ancestry have less central adiposity

New technique could help reduce chances of drug failure during later stages of clinical trials

BRCA gene mutations raise risk of breast, ovarian and other cancers

Dr Anjali Mahto explains how to prevent risk of mosquito bites

New mouse model offers more insight into development of ASD in humans

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Correcting defective p73 gene function may be promising therapeutic strategy for chronic lung diseases

Buck researchers identify new, potential drug targets for sporadic PD

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

Recent research gives more insight into genetics of FASD

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

Cigarette smoke promotes bacteria colonization, immune invasion

New research in mice provides better understanding of how HD begins and develops

Cryptococcus research: an interview with Associate Professor Kirsten Nielsen

New study explores sexual assault victimization among bisexual, gay college students

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News