B Cell News and Research

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Y chromosome loss linked to poor cancer outcomes

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

4 Jun 2025

American Heart Association fellowship supports study of protein linking obesity and heart disease

At home in Australia, Mark Renton started playing football as soon as he could. He figured it would eventually lead to a career prescribing strength training and exercise regimens to athletes.

4 Jun 2025

Understanding how base editing tools work at the molecular level

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

4 Jun 2025

New molecular mechanism offers hope for causal epilepsy treatments

Epilepsy is primarily treated symptomatically - that is, the majority of the available medications aim to suppress seizures without influencing the underlying causes of the disease.

4 Jun 2025

AI and human scientists collaborate to discover new cancer drug combinations

An 'AI scientist', working in collaboration with human scientists, has found that combinations of cheap and safe drugs – used to treat conditions such as high cholesterol and alcohol dependence – could also be effective at treating cancer, a promising new approach to drug discovery.

4 Jun 2025

Variability in blood sugar response depends on individual's metabolic health status

A study led by researchers at Stanford Medicine shows that differences in blood sugar responses to certain carbohydrates depend on details of an individual's metabolic health status.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Researchers map DNA regions that activate liver regeneration

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury or partial resection.

4 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

PCSK9 protein controls how pancreatic cancer cells spread to the lung or liver

A protein called PCSK9 determines how pancreatic cancer cells metastasize to different parts of the body.

4 Jun 2025

Early contact with pet dogs protects genetically susceptible children from eczema

Having a dog at home could help to prevent eczema in children who are genetically prone to the condition, a study suggests.

4 Jun 2025

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members said. They didn't realize the drug could kill her.

4 Jun 2025

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

The SWOG S2302 Pragmatica-Lung trial, which broke new ground with its streamlined pragmatic design, unusually broad eligibility criteria, and reduced data collection, has quickly answered its primary question, finding that the investigational combination it tested did not significantly extend overall survival compared to standard of care treatments.

4 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

New mouse model sheds light on smell loss and neural regeneration

A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost.

3 Jun 2025

Myeloid cells shape tumor microenvironments and influence cancer progression

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments (TME), influencing tumor progression, immune evasion, and therapeutic resistance.

3 Jun 2025

How does norepinephrine influence anxiety-related behaviours?

Discover how microscopy revealed the influence norepinephrine has on anxiety.

From Bruker Nano Surfaces and Metrology 3 Jun 2025

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

FUJIFILM Corporation's Life Sciences Group companies, a portfolio of businesses offering products, services and comprehensive solutions that span all stages of therapeutic development from discovery through to commercialization, today announced new names and identities as part of a strategic positioning effort.

3 Jun 2025

Waters introduces BioResolve Protein A Affinity Columns to accelerate antibody titer measurement, enhancing process agility and batch quality

Waters Corporation today announced the launch of the BioResolve™ Protein A Affinity Columns with MaxPeak™ Premier Technology, providing precise titer measurements.

From Waters Corporation 2 Jun 2025

How soy and gut microbes alter cancer treatment results

Researchers have discovered that plant-derived phytochemicals and their gut microbiome metabolites control the effectiveness of PI3K inhibitors in cancer therapy. The study reveals that dietary components, especially soy compounds processed by gut bacteria, can alter drug metabolism and impact treatment outcomes.

2 Jun 2025

B Cell News and Research

Y chromosome loss linked to poor cancer outcomes

American Heart Association fellowship supports study of protein linking obesity and heart disease

Understanding how base editing tools work at the molecular level

New molecular mechanism offers hope for causal epilepsy treatments

AI and human scientists collaborate to discover new cancer drug combinations

Variability in blood sugar response depends on individual's metabolic health status

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Researchers map DNA regions that activate liver regeneration

Key proteins and pathways drive the success of CAR-T cell therapy

PCSK9 protein controls how pancreatic cancer cells spread to the lung or liver

Early contact with pet dogs protects genetically susceptible children from eczema

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

Navigating the dual role of B cells in tumor immunity

New mouse model sheds light on smell loss and neural regeneration

Myeloid cells shape tumor microenvironments and influence cancer progression

How does norepinephrine influence anxiety-related behaviours?

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

Waters introduces BioResolve Protein A Affinity Columns to accelerate antibody titer measurement, enhancing process agility and batch quality

How soy and gut microbes alter cancer treatment results

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