Immune Response News and Research

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Antibody discovery could explain why so many group A strep vaccines have failed

Researchers at Lund University in Sweden have discovered an antibody with the potential to protect against Strep A infection, as well as a rare form of antibody binding, that leads to an effective immune response against bacteria.

12 Dec 2022

Scientists use single-cell multi-omics data to map disease regulatory circuits

Researchers apply MAGICAL for the identification of modulated host response regulatory circuits in response to Staphylococcus aureus.

12 Dec 2022

Novel drug shows early potential in combating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer Center at the 2022 American Society of Hematology Annual Meeting (Abstract 565).

12 Dec 2022

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

A nasal COVID-19 vaccine based on technology licensed from Washington University in St. Louis has been approved for emergency use in India as a booster for people who have already received two doses of other COVID-19 vaccines.

9 Dec 2022

HIV-positive people are protected by Covid vaccines

People infected with HIV who receive antiretroviral therapy form antibodies against Sars-Cov-2 after being vaccinated against Covid with mRNA vaccines.

9 Dec 2022

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Patients with invasive breast cancer who had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery, according to results of a meta-analysis presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Microbiomes in female reproductive tract linked to pregnancy following use of ART

Specific microbial profiles are associated with better conception rates from assisted reproductive technology.

9 Dec 2022

Estrogen replacement therapy may be a tool to mitigate delirium

Delirium is common among women with urinary tract infections (UTIs) - especially those who have experienced menopause.

8 Dec 2022

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say.

8 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Researchers investigated the immunological mechanisms behind the decreasing efficacy of COVID-19 vaccines by evaluating the durability and magnitude of neutralizing antibodies and memory B and T cell responses to booster doses of mRNA COVID-19 vaccine.

8 Dec 2022

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

Diarrhea is no longer the killer it was in the mid-20th century, when an estimated 4.5 million children under age 5 died of it every year.

7 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

Understanding why respiratory infections are more common in the winter

Researchers investigate the role of extracellular vesicles in the innate nasal mucosal response to several respiratory viruses.

6 Dec 2022

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Nearly three years into the pandemic, many of us now carry antibodies against the virus - due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment.

6 Dec 2022

Immunopeptidome characters of human CoV-OC43-infected cells

Researchers explored T-cell epitopes derived from human seasonal coronavirus OC43.

5 Dec 2022

New insights into how the circadian clock influences T cell responses to vaccination

Research by RCSI University of Medicine and Health Sciences has provided new insights into the mechanism behind how our circadian 24-hour body clock influences our immune response to vaccines, depending on the time of day.

5 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Immune Response News and Research

Antibody discovery could explain why so many group A strep vaccines have failed

Scientists use single-cell multi-omics data to map disease regulatory circuits

Novel drug shows early potential in combating multiple myeloma

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

HIV-positive people are protected by Covid vaccines

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Microbiomes in female reproductive tract linked to pregnancy following use of ART

Estrogen replacement therapy may be a tool to mitigate delirium

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

Cancer immunotherapies can become more potent depending on the time of day

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Understanding why respiratory infections are more common in the winter

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Immunopeptidome characters of human CoV-OC43-infected cells

New insights into how the circadian clock influences T cell responses to vaccination

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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