Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

New report estimates global burden of cancer cases and deaths in 2015

In 2015, there were an estimated 17.5 million cancer cases around the globe and 8.7 million deaths, according to a new report from the Global Burden of Disease Cancer Collaboration published online by JAMA Oncology.

5 Dec 2016

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

4 Dec 2016

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face.

2 Dec 2016

New study finds smoking cessation at any age reduces risk of death

Tobacco use continues to be a major cause of cancer and premature death. Most studies of cigarette smoking and mortality have focused on middle-aged populations, with fewer studies examining the impact of tobacco cessation on disease and mortality risk among the elderly.

30 Nov 2016

Study sheds light on why new drug is effective in combating leukaemia

Researchers at the University of Southampton have shed new light on why and how a new class of drug is effective at fighting off leukaemia.

29 Nov 2016

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania.

29 Nov 2016

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive.

29 Nov 2016

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH).

25 Nov 2016

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy.

23 Nov 2016

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated.

22 Nov 2016

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.

22 Nov 2016

Study offers genetic explanation why cancer occurs commonly in males than females

In a new study, a group of Boston scientists, including researchers at Dana-Farber Cancer Institute, offer a genetic explanation for the age-old conundrum of why cancer is more common in males than females.

22 Nov 2016

Researchers discover protein complex that enables 'quality control' of immune T cells

The research into T cell development within an organ called the thymus revealed for the first time that a protein complex called LUBAC enables 'quality control' of the cells before they are released into the bloodstream.

18 Nov 2016

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors' mutations or being enrolled in clinical trials.

18 Nov 2016

Researchers create first mouse model for common form of infant leukemia

After nearly two decades of unsuccessful attempts, researchers from the University of Chicago Medicine and the Cincinnati Children's Hospital Medical Center have created the first mouse model for the most common form of infant leukemia.

15 Nov 2016

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles, has been awarded a 3 year translational research program grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL).

10 Nov 2016

Leukemia News and Research

Further Reading

New report estimates global burden of cancer cases and deaths in 2015

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Study reveals new way to improve stability of common protein drugs

New study finds smoking cessation at any age reduces risk of death

Study sheds light on why new drug is effective in combating leukaemia

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

Cancer gene mutations can predict response to less intensive treatment in AML patients

HSCI researchers use color tagging system to track development of blood stem cells

Researchers uncover new clues that may help combat leukemia and other B cell cancers

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

Study offers genetic explanation why cancer occurs commonly in males than females

Researchers discover protein complex that enables 'quality control' of immune T cells

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Researchers create first mouse model for common form of infant leukemia

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

ASH partners with other organizations to address knowledge gaps in AML care

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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