Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

MU researchers find more accurate laboratory method for diagnosing pancreatic cancer

Researchers from the University of Missouri have found a more accurate laboratory method for diagnosing pancreatic cancer, the fourth leading cause of cancer death in the United States. The disease causes more than 38,000 deaths each year in the United States, and kills 94 percent of people with the illness within five years, according to the National Cancer Institute.

7 Nov 2013

Normal blood sugar regulation depends on partnership between pancreas and brain

A growing body of evidence suggests that the brain plays a key role in glucose regulation and the development of type 2 diabetes, researchers write in the Nov. 7 issue of the journal Nature.

6 Nov 2013

AGA publishes HCV Clinical Decision Tool for management of HCV-positive patients

The American Gastroenterological Association Clinical Decision Tool for the Screening and Evaluation of Hepatitis C will help gastroenterologists in the early management of HCV-positive patients, according to a new paper in Gastroenterology, the official journal of the American Gastroenterological Association. Chronic HCV has a significant impact on the adult population and is a disease for which much progress has been made in its treatment.

6 Nov 2013

Children's Hospital to participate in drug study to evaluate effects of metformin for treating type 2 diabetes

Children's Hospital Los Angeles will participate in a nationwide drug study evaluating the effects of metformin, a medication that has been shown to be safe and effective for treating type 2 diabetes.

5 Nov 2013

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

4 Nov 2013

Fat recycling system may provide target for future diabetes therapies

The pancreas is a large organ that wraps around our gut, and produces the exact amount of insulin our bodies need when we eat - except when we start to develop diabetes, and insulin production slows down. Sydney scientists describe how a fat recycling system within pancreatic 'beta cells' determines the amount of insulin they secrete, and so may provide a target for future diabetes therapies.

30 Oct 2013

Rituximab drug may be safe, effective for immunoglobulin G4-related disease treatment

Rituximab (Rituxan) — a drug commonly used rheumatoid arthritis, granulomatosis with polyangiitis (formerly Wegener's), and certain types of cancers — may be a safe and effective treatment for immunoglobulin G4-related disease (commonly called IgG4-RD), according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Hopes Raised For Early Pancreatic Cancer Detection

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25 Oct 2013

Study: Investigational drug shows promise against pancreatic cancer

An investigational drug that disrupts tumor blood vessels shows promise against a rare type of pancreatic cancer, scientists at Albert Einstein College of Medicine of Yeshiva University have found. Their results were presented October 20 during a poster session at an international cancer conference.

25 Oct 2013

A simple blood test may reveal the earliest signs of pancreatic cancer

Reporting on a small preliminary study, Johns Hopkins researchers say a simple blood test based on detection of tiny epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because it isn't usually discovered until it has spread to other parts of the body.

23 Oct 2013

Study evaluates role of enteroviruses in human type 1 diabetes

Type 1 diabetes is a disease caused by the destruction of the insulin-producing cells in the pancreas. It is often diagnosed in childhood and requires life-long treatment with daily insulin injections. It is associated with an increased risk for long-term complications which decrease the quality of life and average life-expectancy.

23 Oct 2013

FDA grants orphan drug designation to Aduro's CRS-207 for treatment of pancreatic cancer

Aduro BioTech, Inc. announced today that the Office of Orphan Products Development of the Food and Drug Administration has granted orphan drug designation for CRS-207, a novel immunotherapy, for the treatment of pancreatic cancer.

22 Oct 2013

Endoscopic ultrasound-guided drainage improves outcomes in patients with pseudocysts

Researchers report that in patients with pseudocysts with viscous debris-laden fluid, endoscopic ultrasound-guided drainage by using a combination of a nasocystic drain and transmural stents improves clinical outcomes and lowers the stent occlusion rate compared with those who underwent drainage via stents alone.

22 Oct 2013

Two drug combinations may provide new treatment option for patients with pancreatic cancers

Two drug combinations that simultaneously block two major signaling pathways downstream of the protein KRAS, which is aberrantly active in most pancreatic cancers, may provide a new treatment option for patients with this disease, according to preclinical results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

22 Oct 2013

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

Novo Nordisk today announced that Health Canada has approved Levemir® FlexTouch®, a disposable prefilled insulin pen containing Levemir® (insulin detemir). Levemir® FlexTouch® has been designed to improve ease of use for insulin administration and to help decrease barriers to good treatment adherence for Canadians living with type 1 and type 2 diabetes mellitus (diabetes).

19 Oct 2013

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation , today announced the results of the MPACT phase III clinical trial of ABRAXANE® in combination with gemcitabine were published online in the October 16th edition of the New England Journal of Medicine.

17 Oct 2013

Study aims to identify age-related changes in metabolic pathways

Have you ever wondered why young children can eat bags of Halloween candy and feel fine the next day - compared to adults who experience all sorts of agony following the same junk food binge? Evolution and a gene called Foxo may be to blame. Working in fruit flies, scientists at the Buck Institute have identified a mechanism that helps the flies adapt to changes in diet when they're young; they've discovered that same mechanism gets misregulated as the flies age, disrupting metabolic homeostasis, or balance.

16 Oct 2013

Researchers develop innovative 3D method to grow miniature pancreas from progenitor cells

An international team of researchers from the University of Copenhagen have successfully developed an innovative 3D method to grow miniature pancreas from progenitor cells. The future goal is to use this model to help in the fight against diabetes. The research results has just been published in the scientific journal Development.

16 Oct 2013

Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.

15 Oct 2013

UCLA, Takeda to study how disruption of circadian rhythms promotes type 2 diabetes

Millions of individuals worldwide are exposed to shift work and numerous environmental conditions that disturb circadian clock function and disrupt normal circadian rhythms. Environmental conditions associated with disrupted circadian rhythms greatly increase the risk for development of type 2 diabetes and metabolic syndrome and also hinder the treatment and management of hyperglycemia in existing patients with diabetes.

13 Oct 2013

Pancreas News and Research

Further Reading

MU researchers find more accurate laboratory method for diagnosing pancreatic cancer

Normal blood sugar regulation depends on partnership between pancreas and brain

AGA publishes HCV Clinical Decision Tool for management of HCV-positive patients

Children's Hospital to participate in drug study to evaluate effects of metformin for treating type 2 diabetes

Study: Sugar intake is not directly associated with nonalcoholic fatty liver disease

Fat recycling system may provide target for future diabetes therapies

Rituximab drug may be safe, effective for immunoglobulin G4-related disease treatment

Hopes Raised For Early Pancreatic Cancer Detection

Study: Investigational drug shows promise against pancreatic cancer

A simple blood test may reveal the earliest signs of pancreatic cancer

Study evaluates role of enteroviruses in human type 1 diabetes

FDA grants orphan drug designation to Aduro's CRS-207 for treatment of pancreatic cancer

Endoscopic ultrasound-guided drainage improves outcomes in patients with pseudocysts

Two drug combinations may provide new treatment option for patients with pancreatic cancers

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Study aims to identify age-related changes in metabolic pathways

Researchers develop innovative 3D method to grow miniature pancreas from progenitor cells

Cdk5 protein may play crucial role in deadly form of thyroid cancer

UCLA, Takeda to study how disruption of circadian rhythms promotes type 2 diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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