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Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Research identifies cross-reactive T cells targeting both SARS-CoV-2 and human SNX8 protein, providing insights into the autoimmune mechanisms driving MIS-C in children.

8 Aug 2024

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, "Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival."

8 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

High BPA levels linked to increased prostate cancer risk in older men

A study in Nutrients found that higher urinary bisphenol A (BPA) levels are linked to increased prostate-specific antigen (PSA) and higher prostate cancer risk in senior American men. This suggests a need for heightened cancer screening, especially in high-risk groups.

8 Aug 2024

Study reveals key brain cells help resist food temptations in favor of exercise

Hypocretin/orexin neurons (HONs) are crucial for resisting temptation and choosing exercise over highly palatable foods. This finding highlights potential targets for promoting physical activity and combating obesity.

7 Aug 2024

Sensory nerves drive breast cancer growth and spread, study reveals

Cancer doesn't grow in a vacuum - each tumor grows in a particular microenvironment within the body and spreads through a tangled web of vasculature and nerves.

7 Aug 2024

New research uncovers mechanisms behind heart damage from CTLA-4 blockade

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a protein receptor on T immune cells that prevents the cells from killing other cells, such as cancer cells.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

How social drinking and dopamine influence alcohol-induced euphoria in fruit flies

Grab a drink with friends at happy hour and you're likely to feel chatty, friendly and upbeat. But grab a drink alone and you may experience feelings of depression.

6 Aug 2024

New compound ZTA-26 could be a game-changer in lipid metabolism regulation

Scientists at Nagoya University in Japan have made a significant breakthrough in treating lipid disorders.

6 Aug 2024

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

Ten years of work, and a little help from the green mamba snake, has resulted in a promising new drug that is already being tested in clinical trials.

5 Aug 2024

Dr. Carrie Elks receives $1.4 million NIDDK grant to explore fat cell communication and insulin resistance

The National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases, or NIDDK, awarded Pennington Biomedical researcher Dr. Carrie Elks a grant of $1.4 million to explore insulin resistance and inflammation in fat cells.

5 Aug 2024

Receptor News and Research

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

Review of fasting-mimicking diets in cancer treatment

High BPA levels linked to increased prostate cancer risk in older men

Study reveals key brain cells help resist food temptations in favor of exercise

Sensory nerves drive breast cancer growth and spread, study reveals

New research uncovers mechanisms behind heart damage from CTLA-4 blockade

METRNL protein identified as key player in cancer progression

How social drinking and dopamine influence alcohol-induced euphoria in fruit flies

New compound ZTA-26 could be a game-changer in lipid metabolism regulation

Breakthrough MS drug uses green mamba venom discovery to promote myelin repair

Dr. Carrie Elks receives $1.4 million NIDDK grant to explore fat cell communication and insulin resistance

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Breakthrough study identifies mechanisms behind glucocorticoid resistance in pediatric B-ALL

Cannabigerol shows promise in reducing anxiety and stress, study finds

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Rising cancer rates in younger generations signal urgent need for early-life prevention strategies

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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