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Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

LOEWE, the federal state of Hesse's research promotion program for the development of scientific and economic excellence, is providing €4.8 million in funding for a new research network spearheaded by Goethe University.

28 Jun 2024

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes.

28 Jun 2024

New study reveals how GLP-1 receptor agonists enhance preingestive fullness

GLP-1 receptor agonists promote the feeling of fullness before eating via neurons in the dorsomedial hypothalamus, according to a new study. The findings offer new insights into the neural pathways by which GLP-1 receptor agonists increase the feeling of fullness to prevent overconsumption of food, which is key in mitigating obesity. Glucagon-like-peptide-1 (GLP-1) plays an important role in signaling the feeling of fullness after eating.

27 Jun 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

27 Jun 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

A unifying marker streamlines macrophage research across age and sex

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. However, identifying and studying macrophage activation has been challenging due to the complex nature of these cells and their responses.

27 Jun 2024

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Combining exercise with GLP-1 RA liraglutide results in significant weight loss while preserving bone health in adults with obesity.

27 Jun 2024

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

A study in "Nutrients" explores how rapeseed diacylglycerol oil (RDG) affects fat accumulation and metabolism in obese mice, showing significant benefits in reducing obesity-related indices and improving lipid metabolism.

26 Jun 2024

Atogepant may decrease the risk of developing rebound headache in people with migraine

A drug used to prevent migraine may also be effective in people with migraine who experience rebound headaches, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

CSF1R marker enables study of Macrophage Activation Mosaicism

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair.

26 Jun 2024

Differences in effectiveness among antihyperglycemic drugs on dementia risk identified in recent study

Researchers compare the effectiveness of anti-diabetes medications in reducing the risk of dementia in older diabetics.

26 Jun 2024

Study finds women lost more of their body weight on average with semaglutide than men

Researchers performed a secondary analysis of the semaglutide treatment effect in people with obesity and heart failure with a preserved left ventricular ejection fraction program that included individuals with diabetes mellitus, stratified by biological sex.

26 Jun 2024

New drug tirzepatide significantly improves sleep apnea and weight loss

The effects of tirzepatide on adults with obesity and moderate-to-severe obstructive sleep apnea.

26 Jun 2024

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

26 Jun 2024

Semaglutide proves a game-changer for kidney and heart health in diabetes patients

The FLOW trial demonstrated that semaglutide significantly improves kidney and cardiovascular outcomes in people with chronic kidney disease and type 2 diabetes, irrespective of SGLT2 inhibitor use.

25 Jun 2024

Study reveals novel therapeutic approach for excessive alcohol use

In a significant finding, researchers from The Jackson Laboratory (JAX) and UConn Health have discovered that sodium valerate, a short-chain fatty acid produced by gut microbes, can dramatically reduce binge drinking behavior and blood ethanol concentration in mice.

25 Jun 2024

Receptor News and Research

Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

New study reveals how GLP-1 receptor agonists enhance preingestive fullness

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

A unifying marker streamlines macrophage research across age and sex

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Rapeseed diacylglycerol oil may combat obesity by enhancing lipid metabolism

Atogepant may decrease the risk of developing rebound headache in people with migraine

CSF1R marker enables study of Macrophage Activation Mosaicism

Differences in effectiveness among antihyperglycemic drugs on dementia risk identified in recent study

Study finds women lost more of their body weight on average with semaglutide than men

New drug tirzepatide significantly improves sleep apnea and weight loss

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

Semaglutide proves a game-changer for kidney and heart health in diabetes patients

Study reveals novel therapeutic approach for excessive alcohol use

Combining CYFRA 21-1 with CXCR1 and cxcr2 levels for predicting recurrence in stage III squamous cell lung carcinoma

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Study sheds light on the role of signaling pathway in the brain to prevent neuroinflammation

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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