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Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Canadian researchers use gene therapy to treat patient with Fabry disease

A team of Canadian physicians and researchers is believed to be the first in the world to have used gene therapy to treat a patient with Fabry disease, a rare inherited enzyme deficiency that can damage major organs and shorten lifespan.

16 Feb 2017

Radiotherapy for breast cancer linked to greater risk of second primary lung cancer

East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer.

16 Feb 2017

Postmenopausal hormone therapy lasting longer than ten years linked to lower dementia risk

Postmenopausal estrogen-based hormone therapy lasting longer than ten years was associated with a decreased risk of Alzheimer's disease in a large study carried out at the University of Eastern Finland.

16 Feb 2017

Paxman's scalp cooling system shows to successfully reduce alopecia during chemotherapy in breast cancer patients

The results of Paxman’s first randomised US scalp cooling trial has been published in JAMA; a renowned peer-reviewed oncology medical journal published by the American Medical Association.

From Paxman 16 Feb 2017

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys

Scientists at the National Institutes of Health have found that the presence of the protein alpha-4 beta-7 integrin on the surface of HIV and its monkey equivalent--simian immunodeficiency virus, or SIV--may help explain why an antibody protected monkeys from SIV in previous experiments.

16 Feb 2017

New report highlights serious health problems faced by spinal cord injury patients

Paralysis is just one of the many serious health problems faced by patients who suffer spinal cord injuries.

16 Feb 2017

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

More than six decades after Castleman disease was first described, a group of experts from Penn Medicine and other institutions around the world has established the first set of diagnostic criteria for a life-threatening subtype of the condition, idiopathic multicentric CD, which is often misdiagnosed as other illnesses.

16 Feb 2017

Gene therapy treats myotubular myopathy in dogs

The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

16 Feb 2017

IDIBELL scientists develop oncolytic virus capable of redirecting immune system to attack cancer cells

Researchers of the Cancer Virotherapy Research Group of Bellvitge Biomedicine Research Institute, led by Dr. Ramon Alemany, have developed an oncolytic virus capable of redirecting the patient's immune system against their tumor cells.

16 Feb 2017

Salk scientists use mRNA to successfully treat hemophilia B in mice

FedEx, UPS, DHL--when it comes to sending packages, choices abound. But the most important delivery service you may not have heard of mRNA.

16 Feb 2017

IDSA guidelines: Team approach vital to successful treatment of complex neurological infections

A team approach is vital to the successful diagnosis and treatment of complex neurological infections related to placement of devices in the brain, or as a result of neurosurgery or head trauma.

16 Feb 2017

Hormone therapy may not protect women from Alzheimer's disease, new study shows

The latest study on hormone therapy and Alzheimer's disease shows no relationship between taking the drugs and whether you may develop the disease years later.

15 Feb 2017

Yale researchers find potential new way to combat brain cancer

A recent Yale study may have found a new way to fight brain cancer.

15 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

FDA approves new drug to treat adults with moderate-to-severe plaque psoriasis

The U.S. Food and Drug Administration today approved Siliq (brodalumab) to treat adults with moderate-to-severe plaque psoriasis. Siliq is administered as an injection.

15 Feb 2017

Combination of drugs amplifies kill rates of brain cancer tumours in mice

A promising combination of immunotherapies delivers a one-two punch to brain cancer tumours with high cure rates in mice, scientific evidence published in Nature Communications today says.

15 Feb 2017

New clinical practice guideline provides evidence-based analyses of specific insomnia drugs

A new clinical practice guideline is the first from the American Academy of Sleep Medicine to provide comprehensive, evidence-based analyses of individual agents commonly used in the treatment of chronic insomnia disorder.

14 Feb 2017

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Penn Medicine's Orphan Disease Center announces a new partnership with FAST to study gene therapy approaches to treat Angelman syndrome.

14 Feb 2017

Scientists identify how imbalance of calcium in mitochondria may contribute to Alzheimer's disease

Calcium in the mitochondria -- the energy factory of cells -- may be one of the keys to understanding and treating Alzheimer's disease and dementia.

14 Feb 2017

Therapy News and Research

Glowing mice could mark major step forward for new gene therapy

Canadian researchers use gene therapy to treat patient with Fabry disease

Radiotherapy for breast cancer linked to greater risk of second primary lung cancer

Postmenopausal hormone therapy lasting longer than ten years linked to lower dementia risk

Paxman's scalp cooling system shows to successfully reduce alopecia during chemotherapy in breast cancer patients

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys

New report highlights serious health problems faced by spinal cord injury patients

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

Gene therapy treats myotubular myopathy in dogs

IDIBELL scientists develop oncolytic virus capable of redirecting immune system to attack cancer cells

Salk scientists use mRNA to successfully treat hemophilia B in mice

IDSA guidelines: Team approach vital to successful treatment of complex neurological infections

Hormone therapy may not protect women from Alzheimer's disease, new study shows

Yale researchers find potential new way to combat brain cancer

Signals from fat cells may aid in diagnostics for metabolic conditions

FDA approves new drug to treat adults with moderate-to-severe plaque psoriasis

Combination of drugs amplifies kill rates of brain cancer tumours in mice

New clinical practice guideline provides evidence-based analyses of specific insomnia drugs

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Scientists identify how imbalance of calcium in mitochondria may contribute to Alzheimer's disease

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

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