Protein C News and Research

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Targeting amino acid transporter may improve survival rates for non-small cell lung cancer patients

An amino acid transporter named xCT may affect the growth and progression of non-small cell lung cancer, a discovery that may predict the five-year survival rate of patients suffering from this cancer, now at 16 percent, researchers at Georgia State University and Vanderbilt University Medical Center have concluded.

11 Jul 2018

Study could help explain how synapses may be made weaker or stronger

To work at all, the nervous system needs its cells, or neurons, to connect and converse in a language of electrical impulses and chemical neurotransmitters.

11 Jul 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Researchers discover mechanism that shuts down cell-to-cell communications pathway

Cellular functions rely on several communications networks that allow cells to rapidly respond to signals affecting the organism.

10 Jul 2018

New approach could greatly enhance people's long-term tolerance for transplants

Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant.

10 Jul 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

Bruker's MALDI Biotyper OMA receives AOAC Method of the Year award in food microbiology

At the 2018 Annual Meeting of the International Association of Food Protection (www.foodprotection.org/), Bruker announces a standardized workflow for any microbial isolate confirmation and identification in food microbiology.

From Bruker Daltonics 10 Jul 2018

Researchers design artificial intelligence system for predicting drug combinations' side effects

Last month alone, 23 percent of Americans took two or more prescription drugs, according to one CDC estimate, and 39 percent over age 65 take five or more, a number that's increased three-fold in the last several decades.

10 Jul 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

New TSPO-targeted PET imaging more fully evaluates extent of rheumatoid arthritis

A new positron emission tomography imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein expression in the synovium (joint lining tissue).

10 Jul 2018

Fluorescent fish could help find origins of neuroblastoma

A new type of zebrafish that produces fluorescent tags in migratory embryonic nerve precursor cells could help a Rice University neurobiologist and cancer researcher find the origins of the third-most common pediatric cancer in the U.S.

10 Jul 2018

Altitude sickness drug may offer significant gains for patients with glioblastoma

A drug used to treat altitude sickness -- as well as glaucoma, epilepsy, heart failure and seizures -- may also offer significant gains for patients with a fast-growing brain tumor known as glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.

10 Jul 2018

Mice study shows promise for treating genetic conditions during fetal development

Researchers at Carnegie Mellon University and Yale University have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model.

10 Jul 2018

New theory on Huntington's disease shows promise to open new avenues of drug development

McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.

10 Jul 2018

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

Ludwig-developed antibody drug for deadly brain cancer may have broader applications

A Ludwig Cancer Research study explains why a particular mutation in the epidermal growth factor receptor, a cell surface protein, results in more aggressive tumors and poorer overall survival of patients diagnosed with the brain cancer glioblastoma multiforme.

10 Jul 2018

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs.

9 Jul 2018

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

A research team from the UAB led by Professor Fatima Bosch has managed to cure obesity and type 2 diabetes in mice using gene therapy.

9 Jul 2018

Protein C News and Research

Targeting amino acid transporter may improve survival rates for non-small cell lung cancer patients

Study could help explain how synapses may be made weaker or stronger

Mature kidney podocytes for developing cell therapies and drug discovery

Researchers use genome editing to reduce cholesterol levels in animal model

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers discover mechanism that shuts down cell-to-cell communications pathway

New approach could greatly enhance people's long-term tolerance for transplants

Fluorescent zebrafish genes provide clues about neuroblastoma

Bruker's MALDI Biotyper OMA receives AOAC Method of the Year award in food microbiology

Researchers design artificial intelligence system for predicting drug combinations' side effects

Study identifies constellation of metabolites linked to ME/CFS

New TSPO-targeted PET imaging more fully evaluates extent of rheumatoid arthritis

Fluorescent fish could help find origins of neuroblastoma

Altitude sickness drug may offer significant gains for patients with glioblastoma

Mice study shows promise for treating genetic conditions during fetal development

New theory on Huntington's disease shows promise to open new avenues of drug development

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Ludwig-developed antibody drug for deadly brain cancer may have broader applications

Spread of pancreatic cancer to the liver or lungs depends on plasticity of tumor cells

Researchers use gene therapy to cure obesity and type 2 diabetes in mice

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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