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Tiny transport vesicles and shifts in metabolism can signal big changes in cancer tissues

Microscopic shifts in metabolism and increases in tiny transport vesicles out of tumor cells preface larger changes to the tumor environment and could prepare the way for cancerous cells to spread and metastasize, University of Illinois researchers report.

28 Jan 2017

Psychosomatic research findings may provide insights into unexplained and difficult to treat disorders

In the current issue of Psychotherapy and Psychosomatic Dr. Giovanni A. Fava and collaborators describe research findings that may shed new light on unexplained and difficult to treat medical disorders.

28 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

28 Jan 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Single-molecule compounds may become basis for new antioxidant therapies

Treated particles of graphene derived from carbon nanotubes have demonstrated remarkable potential as life-saving antioxidants, but as small as they are, something even smaller had to be created to figure out why they work so well.

28 Jan 2017

Both accelerator and brake in the brain control all types of movements, research shows

In order to drive a car, you need a good balance between accelerator and brake. The same applies to a part of the brain - the striatum - that controls our movements.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

In patients with severe obstructive sleep apnea (OSA), oral appliances that treat the condition by moving the lower jaw forward appear to improve sleep but not reduce key risk factors for developing heart and other cardiovascular disease, according to new research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

28 Jan 2017

Hemodialysis patients do not wish to receive treatment for depression, study shows

Many patients with kidney failure who are receiving chronic hemodialysis have depressive symptoms but do not wish to receive aggressive treatment to alleviate them, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

28 Jan 2017

Joslin scientists suggest new approach to improve stroke therapy

The standard of care for treating strokes caused by blood clots involves the therapeutic infusion of tissue plasminogen activator (tPA), which can help to dissolve the clots and restore blood flow.

27 Jan 2017

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

A bacterial by-product known to be important in maintaining gut health may slow the progression of amyotrophic lateral sclerosis, or ALS - a progressive, neurodegenerative disease.

27 Jan 2017

DCIS patients more likely to be alive ten years later than women in general population

Women over 50 who have been treated for ductal carcinoma in situ (DCIS) are more likely to be alive ten years later than women in the general population, according to new research presented at the European Cancer Congress 2017.

27 Jan 2017

ADT for treating advanced prostate cancer not linked to increased risk of Alzheimer disease

A large-scale, population based study led by Dr. Laurent Azoulay, Senior Investigator with the Lady Davis Institute at the Jewish General Hospital, has concluded that the use of androgen deprivation therapy (ADT) to treat advanced prostate cancer is not associated with an increased risk of Alzheimer disease.

27 Jan 2017

Study focuses on benefit of continuous glucose monitoring for diabetes patients on MDI insulin therapy

Dexcom announces the first and only randomised, controlled study focusing solely on the benefit of continuous glucose monitoring (CGM) for diabetes patients on multiple daily injections (MDI) insulin therapy.

27 Jan 2017

Lancet study: Advanced MRI doubles detection of aggressive tumours

A study published in The Lancet on 19th January 2017 entitled ‘Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study’ shows that using advanced MRI almost doubles the number of aggressive tumours detected.

27 Jan 2017

Treating subclinical hypothyroidism can reduce pregnancy loss, study shows

When a woman becomes pregnant, many changes occur in her body. One of those changes is in the levels of various hormones produced by the body.

27 Jan 2017

New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

27 Jan 2017

Study compares postoperative outcomes, costs of laparoscopic and open antireflux surgery for GERD

Patients with gastroesophageal reflux disease, known as GERD, who undergo laparoscopic anti-reflux operations compared with traditional "open" operations suffer fewer postoperative complications, experience faster recovery, and incur lower health care costs, according to study results published online as an "article in press" on the Journal of the American College of Surgeons website, ahead of print publication.

27 Jan 2017

Therapy News and Research

Tiny transport vesicles and shifts in metabolism can signal big changes in cancer tissues

Psychosomatic research findings may provide insights into unexplained and difficult to treat disorders

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

GUMC researchers describe lab technique to fill gaps in clinical care and research

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Single-molecule compounds may become basis for new antioxidant therapies

Both accelerator and brake in the brain control all types of movements, research shows

UAB researchers find how gut fails to prevent HIV-1 infection

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

Hemodialysis patients do not wish to receive treatment for depression, study shows

Joslin scientists suggest new approach to improve stroke therapy

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

DCIS patients more likely to be alive ten years later than women in general population

ADT for treating advanced prostate cancer not linked to increased risk of Alzheimer disease

Study focuses on benefit of continuous glucose monitoring for diabetes patients on MDI insulin therapy

Lancet study: Advanced MRI doubles detection of aggressive tumours

Treating subclinical hypothyroidism can reduce pregnancy loss, study shows

New gene therapy for Pompe disease may replace currently available treatments

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Study compares postoperative outcomes, costs of laparoscopic and open antireflux surgery for GERD

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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