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Usefulness of C-reactive protein test questioned

Researchers with Dartmouth Medical School and the Veterans Affairs Outcomes Group at the White River Junction (Vt.) VA Medical Center are questioning the usefulness of the C-Reactive Protein (CRP) test for guiding decisions about the use of cholesterol-lowering medication.

27 Feb 2007

Depression linked with a specific autoantibody and central nervous system dysfunction in lupus

Systemic lupus erythomatosus (SLE), often simply called lupus, is a complex autoimmune disease marked by joint pain, skin rashes, extreme fatigue, and depression, among other symptoms.

27 Feb 2007

First 3-D structure from key influenza protein revealed

In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world.

27 Feb 2007

Stimuvax investigational lung cancer vaccine phase III study starts

Merck KGaA today announced that the first patient has been enrolled in its global Phase III clinical study, START (Stimulating Targeted Antigenic Responses To NSCLC), assessing the efficacy and safety of Stimuvax (BLP25 liposome vaccine) as a potential treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC).

26 Feb 2007

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

Short pieces of RNA, known as small interfering RNA (siRNA), have the potential to become a new class of anticancer drugs if researchers can solve the problem of how to deliver these fragile molecules to cancer cells.

26 Feb 2007

Quantum rods and dots image cancer cells

Brightly fluorescent quantum dots and quantum rods are quickly becoming important tools for identifying specific molecules and cells in living systems. Two new reports demonstrate some of the ways in which cancer researchers are using these nanoscale imaging agents.

26 Feb 2007

Genetically caused deafness may be reversible by compensating for a missing protein

Emory University researchers have found that in mice, increasing the amount of the protein connexin26 in the ear's cochlea compensates for an absence of another protein, connexin30.

26 Feb 2007

Diet rich in black soya beans could help control weight, lower fat and cholesterol levels

Yellow soya has already been hailed for its cholesterol lowering capabilities; this is one of the reasons why frozen food manufacturer Birds Eye has added the beans to its range. However, a team of Korean researchers has shown that black soya may be even more potent in rats, and also prevents weight gain.

26 Feb 2007

microRNA directly regulates a gene implicated in human cancers

MicroRNAs are tiny snippets of RNA that can repress activity of a gene by targeting the gene's messenger RNA (which copies DNA information and starts the process of protein production).

22 Feb 2007

Research defines the cancer role for protein Gab-2

A protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease's deadliest stage, a study from Burnham Institute for Medical Research has found.

22 Feb 2007

Apolipoprotein C1 protein linked to elevated BMI in people of American Indian and Mexican ancestry

University of Minnesota researchers have discovered a variant of a common blood protein, apolipoprotein C1, in people of American Indian and Mexican ancestry that is linked to elevated body mass index (BMI), obesity and Type 2 diabetes.

22 Feb 2007

New understanding of how and why Taxol works in patients with breast cancer

Cancer researchers at Georgetown University Medical Center have taken a step towards understanding how and why a widely used chemotherapy drug works in patients with breast cancer.

22 Feb 2007

Experimental vector vaccine reduces stillbirths from cytomegalovirus

Researchers funded by the National Institutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV) - a common virus that can also cause mental retardation and hearing loss in newborn children who were infected in early fetal life.

21 Feb 2007

Imaging of disease dynamics during meningococcal sepsis

Each year 170,000 people around the world die of this type of meningitis, according to the World Health Organization, (WHO).

21 Feb 2007

New test identifies suitable lymphoma patients likely to respond to new therapy

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered a genetic signature identifying cases of lymphoma that are uniquely susceptible to a newly developed molecular targeted therapy. As a result, physicians organizing clinical trials of the new therapy will be able to enroll patients who'll be most likely to benefit from it.

20 Feb 2007

Translationally controlled tumor protein key to organ growth

When amounts of a small protein called TCTP (translationally controlled tumor protein) are reduced in the cells of fruit flies, they are smaller than normal, indicating that the protein plays a major role in the growth and proliferation of cells, said researchers at Baylor College of Medicine in a report in current issue of the journal Nature.

20 Feb 2007

Chemotherapy drug bortezomib packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.

20 Feb 2007

Low levels of RANTES protein in the blood is a predictor of cardiac death

Researchers at SUNY Downstate Medical Center in Brooklyn have determined that low levels of a protein in the blood is a predictor of cardiac death in patients with coronary artery disease.

20 Feb 2007

Researchers discover markers that identify breast cancer subtypes resistant to Herceptin

Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor.

20 Feb 2007

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein.

20 Feb 2007

G Protein News and Research

Usefulness of C-reactive protein test questioned

Depression linked with a specific autoantibody and central nervous system dysfunction in lupus

First 3-D structure from key influenza protein revealed

Stimuvax investigational lung cancer vaccine phase III study starts

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

Quantum rods and dots image cancer cells

Genetically caused deafness may be reversible by compensating for a missing protein

Diet rich in black soya beans could help control weight, lower fat and cholesterol levels

microRNA directly regulates a gene implicated in human cancers

Research defines the cancer role for protein Gab-2

Apolipoprotein C1 protein linked to elevated BMI in people of American Indian and Mexican ancestry

New understanding of how and why Taxol works in patients with breast cancer

Experimental vector vaccine reduces stillbirths from cytomegalovirus

Imaging of disease dynamics during meningococcal sepsis

New test identifies suitable lymphoma patients likely to respond to new therapy

Translationally controlled tumor protein key to organ growth

Chemotherapy drug bortezomib packs a one-two punch

Low levels of RANTES protein in the blood is a predictor of cardiac death

Researchers discover markers that identify breast cancer subtypes resistant to Herceptin

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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