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Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Researchers identify new form of depression

In a new study, researchers from Hiroshima University have identified a new form of depression that could be used to inform a new generation of treatments.

11 Jun 2018

Research drug may one day be novel treatment for systemic inflammatory response syndrome

When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection.

11 Jun 2018

New study shows health impacts of eating plant-based diet

Eating a vegetarian or primarily plant-based diet is associated with a variety of health benefits. But simply being vegetarian is not enough to reap those benefits - the quality of the food matters, too.

11 Jun 2018

Researchers identify enzyme that controls cell’s collagen secretion

Researchers at Tokyo Institute of Technology have identified an enzyme that controls how much our cells secrete collagen.

11 Jun 2018

Nature and effects of breastfeeding on health of mothers and babies

Guidelines recommend breastfeeding as the best source of nutrition for most babies. The Nutrition 2018 meeting will feature new research findings on the nature of breast milk and how breastfeeding may affect the health of both moms and babies.

11 Jun 2018

Researchers reverse tau-induced memory deficits in animal models

Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the way of significant clinical advance.

8 Jun 2018

High-sensitive troponin T detects more cardiac infarctions than conventional ones, shows study

Five percent more cardiac infarctions detected and 11 percent fewer patients suffering a relapse. That is the result of a study of more than 80,000 patients in which two cardiac damage markers were compared with each other.

8 Jun 2018

Scientists find role of schizophrenia gene in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

8 Jun 2018

Green, nutrient-rich broccoli lattes may be on the horizon

Green, nutrient-rich coffees may be on the horizon after researchers have developed a powder made from imperfect-looking broccoli that would have previously been wasted.

8 Jun 2018

New research provides clues into development of mammalian cerebral cortex

The cerebral cortex - the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness - has fascinated neuroscientists for centuries.

8 Jun 2018

Scientists find key biomarker of Parkinson's disease in the retina

A research involving scientists from the University of Alicante and the United States notes that the accumulation of a protein known as alpha-synuclein in the retina is a key Parkinson's biomarker that could help detect the degree of severity of the disease.

8 Jun 2018

Some tumors use two levels of protection against immune system, shows study

In research published today, Babraham Institute researchers have shown that some tumors use not one but two levels of protection against the immune system.

8 Jun 2018

Researchers discover protein responsible for X chromosome inactivation

Researchers have discovered that the structural protein SMCHD1 is required to prevent genes from both X chromosomes being expressed in female mammals.

7 Jun 2018

Study: Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain

Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain, making it more resilient to the physical and behavioral effects of stress, according to new research by University of Colorado Boulder scientists.

7 Jun 2018

Targeting strategy may pave way for improved drug delivery to cancer cells

Bioengineers may be able to use the unique mechanical properties of diseased cells, such as metastatic cancer cells, to help improve delivery of drug treatments to the targeted cells, according to a team of researchers at Penn State.

7 Jun 2018

Rural and urban microbiota differ from a young age, finds new study

A new study has shown that differences in the human gut microbiome between people living in rural versus urban areas of Nigeria begin at a very young age.

7 Jun 2018

Researchers identify biomarkers that may predict risk of osteolysis

Hip replacements relieve pain and restore mobility for hundreds of thousands of patients in the United States each year, but of the more than 400,000 hip replacements performed in the U.S. annually, about 10 percent will fail within 10 to 15 years.

7 Jun 2018

Researchers look for deeper explanations into causes of Alzheimer's disease

For more than 20 years, much of the leading research on Alzheimer's disease has been guided by the "amyloid hypothesis."

7 Jun 2018

Overload of zinc in muscles leads to cachexia in cancer patients

It's estimated that nearly one-third of all cancer deaths are caused not by the cancer itself but by cachexia - a debilitating muscle-wasting syndrome that affects an estimated 80 percent of advanced cancer patients. Cachexia is linked to reduced tolerance for cancer therapy, poor quality of life, and accelerated death, but there are no effective treatments and its cause is still largely unknown.

6 Jun 2018