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Bacteria release membrane-derived vesicles that may have different functions during infection

Bacteria release membrane-derived vesicles (MVs), which are small particles that can transport virulence factors to neighboring bacteria or to the cells of a mammalian host. This special MV-based system for delivering toxic proteins and nucleic acids in a protected manner to the target cells may have different specific functions depending on whether the bacterium acts as an extracellular or intracellular pathogen.

18 Sep 2017

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

The largest genomic profiling study ever conducted into a type of brain tumor known as glioma in children has identified genetic alterations in 96% of cases. As reported in The Oncologist, this genetic information could help to identify the most effective treatments for specific cases of glioma, hopefully improving the prognosis for what is currently the leading cause of death for children with cancer in the US.

18 Sep 2017

Global Burden of Disease study reveals latest findings on state of world’s health

Today, the Global Burden of Disease study publishes its latest global estimates for the state of the world’s health in The Lancet. The GBD is the only annual, comprehensive, peer-reviewed assessment of global trends in health, providing global and national estimates on more than 330 diseases, causes of death, and injuries in 195 countries and territories worldwide.

18 Sep 2017

Continuous glucose monitoring for pregnant women with type 1 diabetes reduces risk of complications for newborns

For women with type 1 diabetes, monitoring blood sugar levels continuously during pregnancy via an implanted device helps better manage the disease, and improves birth outcomes compared to traditional finger-prick tests, according to a new randomized trial published in The Lancet and presented at the European Association for the Study of Diabetes conference.

18 Sep 2017

Carbohydrates on surface of malaria parasites could be key to effective vaccine

An international research team has shown for the first time that carbohydrates on the surface of malaria parasites play a critical role in malaria's ability to infect mosquito and human hosts.

18 Sep 2017

Medical marijuana rarely addressed in medical education

Although 29 states and the District of Columbia allow marijuana use for medical purposes, few medical students are being trained how to prescribe the drug.

15 Sep 2017

Categories of Preference included for recommendations within NCCN Guidelines

The National Comprehensive Cancer Network has instituted Categories of Preference for recommendations within the NCCN Clinical Practice Guidelines in Oncology. Initially, Categories of Preference will be published for drugs and biologics recommended within the NCCN Guidelines® for Multiple Myeloma.

15 Sep 2017

Doctors and older patients should work together to dial back diabetes treatment, study suggests

Anyone with diabetes who takes blood sugar medication knows their doctor prescribed it to help them. After all, the long-term effects of elevated blood sugar can harm everything from the heart and kidneys to the eyes and feet.

15 Sep 2017

Child with abdominal pain more likely to receive CT scan in general ED, study finds

A child with non-traumatic abdominal pain, a common symptom of appendicitis, is more likely to receive a computed tomography (CT) scan in a general emergency department (ED) than if he or she visited a pediatric emergency department, according to a study published in Pediatrics.

15 Sep 2017

Funding cuts damaging young people's access to mental health services, say researchers

Funding cuts and austerity measures are damaging young people's access to mental health services, with potentially long-term consequences for their mental wellbeing, say researchers at the University of Cambridge.

15 Sep 2017

Research finds postpartum depressive symptoms in 45% of parents when newborns leave NICU

Almost half of parents whose children were admitted to Children's National Health System's neonatal intensive care unit experienced postpartum depressive symptoms, anxiety, and stress when their newborns were discharged from the hospital.

15 Sep 2017

Clinicians could provide support to address unique social needs of immigrant children

The grade school student has been a patient for a while, but during a routine visit, 9-year-old Pedro finally confides that he has had headaches and difficulty concentrating in school for weeks now. Pedro tells you he worries that his older brother--among those granted Deferred Action for Childhood Arrivals--and his parents, undocumented immigrants, "will disappear" while he attends class.

15 Sep 2017

Quality-improvement initiative could enhance safety of newborns, provide significant savings

Sick newborns often rely on a ventilator to supply oxygen and are tethered to the life-saving device by a plastic endotracheal tube. The American Academy of Pediatrics has counseled health care providers that ordering a chest X-ray daily simply to verify positioning of the ETT ratchets up costs without improving patient safety.

15 Sep 2017

Penn study provides insight into how cells maintain identity during replication

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time.

15 Sep 2017

Study examines effectiveness of placebo and antidepressants in children, adolescents

Although the clinical efficacy of antidepressants in children and adolescents is proven, it is frequently accompanied by side effects. In addition, the influence of the placebo effect on the efficacy of antidepressants is unclear.

15 Sep 2017

Study highlights complexity of childhood cancer survivors’ medical needs

Survivors of childhood cancer may experience, on average, nearly twice as many chronic health condition by the age of 45, compared to the general population, according to a new study led by St Jude Children’s Research Hospital (USA) and published in The Lancet.

15 Sep 2017

Studies reveal link between autism and severe maternal infection during pregnancy

Two studies conducted at the Massachusetts Institute of Technology (MIT) and the University of Massachusetts Medical School indicated that mothers who were affected with severe infections that required hospitalization are at an increased risk of having an autistic child.

15 Sep 2017

Patients and families save time and money with telemedicine visits

Patients and families who use telemedicine for sports medicine appointments saved an average of $50 in travel costs and 51 minutes in waiting and visit time, according to a new study by Nemours Children's Health System. Each telemedicine visit also saved the health system an average of $24 per patient, researchers reported at the American Academy of Pediatrics National Conference & Exhibition.

15 Sep 2017

Research finds link between caregiver’s gender, relationship and severity of child abuse injuries

Efforts to prevent child abuse by people who care for children should extend to additional categories of caregivers since injuries that children suffer at the hands of their parent's male partner, babysitter or daycare worker are likely to be more severe, according to research presented during the 2017 American Academy of Pediatrics national conference.

15 Sep 2017

Regions with stronger firearm laws have lower rates of ED visits for pediatric gun-related injuries

Regions of the United States with stronger firearm legislation had lower rates of Emergency Department (ED) visits for pediatric firearm-related injuries, according to a study led by Children's National Health System researchers.

15 Sep 2017

Children News and Research

Bacteria release membrane-derived vesicles that may have different functions during infection

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

Global Burden of Disease study reveals latest findings on state of world’s health

Continuous glucose monitoring for pregnant women with type 1 diabetes reduces risk of complications for newborns

Carbohydrates on surface of malaria parasites could be key to effective vaccine

Medical marijuana rarely addressed in medical education

Categories of Preference included for recommendations within NCCN Guidelines

Doctors and older patients should work together to dial back diabetes treatment, study suggests

Child with abdominal pain more likely to receive CT scan in general ED, study finds

Funding cuts damaging young people's access to mental health services, say researchers

Research finds postpartum depressive symptoms in 45% of parents when newborns leave NICU

Clinicians could provide support to address unique social needs of immigrant children

Quality-improvement initiative could enhance safety of newborns, provide significant savings

Penn study provides insight into how cells maintain identity during replication

Study examines effectiveness of placebo and antidepressants in children, adolescents

Study highlights complexity of childhood cancer survivors’ medical needs

Studies reveal link between autism and severe maternal infection during pregnancy

Patients and families save time and money with telemedicine visits

Research finds link between caregiver’s gender, relationship and severity of child abuse injuries

Regions with stronger firearm laws have lower rates of ED visits for pediatric gun-related injuries

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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